Te Hydroxypropyl methylcellulose (HPMC)He mea nui te cellulose ether kore-ionic e whakamahia whānuitia ana i roto i te hanga, i ngā rongoā, i te kai, me ngā matū o ia rā. Ko te matotoru he tohu matua mō te aromatawai i te kounga me te whaihua o te HPMC. Ehara i te mea ko ngā āhuatanga rheological o tana otinga anake e whakaata ana engari e pā tika ana hoki ki tōna matotorutanga, te pupuri wai, me ngā āhuatanga hanga kiriata. Hei whakarite i te kounga hua ōrite, me mahi te ine matotorutanga mā te whakamahi i tētahi tikanga whakamātautau matotoru pūtaiao me te paerewa.
1. Te Mātāpono Whakamātautau
Ka rewa te HPMC ki te wai hei hanga i tētahi otinga mārama, mārama rānei. Ko tōna matotoru e whakawhirinaki ana ki te nui o te whakapūhui, te nui o te whakakapinga, me te kukū o te otinga. Ka tautuhia e te whakamātautau matotoru ngā āhuatanga rere o tētahi otinga HPMC mā te ine i te waku ā-roto o te otinga i te wā e rere ana i tētahi pāmahana motuhake. Ko te tikanga o ngā inenga he whakamahi i tētahi mita mata hurihuri (momo Brookfield) i tētahi mita mata capillary rānei. Ko te tikanga hurihuri te mea e whakamahia whānuitia ana, nā te mea ka whakaratohia he māramatanga māmā ake mō ngā āhuatanga angiangi-kutikuti o te otinga i ngā tere hurihuri rerekē.
2. Ngā Paerewa Noa me ngā Tikanga Whakamātautau
I tēnei wā, ko te whakamātautau matotoru o te HPMC e hangai ana ki ngā mea e whai ake nei:
Paerewa Hainamana: GB/T 12000 “Ngā Tikanga Whakamātautau Whānui mō ngā Etera Cellulose”
Paerewa US: ASTM D1347 “Ngā Tikanga Whakamātautau Paerewa mō ngā Otinga Cellulose Ether”
Te mahi ahumahi: Ka inehia te matotoru mā te whakamahi i tētahi otinga wai 2% i te 20°C mā te whakamahi i tētahi mita matotoru hurihuri a Brookfield.
Ko te kukū o te wai whakamātautau he 2% (wāhanga papatipu) te tikanga, engari me whakatikatika pea ngā momo HPMC rerekē i te 1%, 2%, teitei ake rānei ngā kukū. Me tino whakahaere te pāmahana whakamātautau i te 20±0.1°C, nā te mea ka pā nui ngā piki me ngā heke o te pāmahana ki ngā pānui matotoru.
3. Tukanga Whakamātautau
3.1. Te Whakarite i te Tauhohenga me te Taputapu
Taurite tātaritanga tika (0.1 mg te tika)
Ine mata hurihuri Brookfield (raupapa LV e wātea ana)
3.2. Kaukau wai pāmahana pumau, taiao rānei e whakahaerehia ana te pāmahana
Wai parakore (e tutuki ana i ngā whakaritenga wai GB/T 6682 Wāhanga III)
Horoia te beaker me te stirer
3.3. Te Whakarite i te Otinga
Paunatia kia tika te 2.00 karamu (± 0.01 karamu) o te tauira HPMC.
Ringihia te 80% o te rōrahi e hiahiatia ana o te wai parakore (tata ki te 80 mL) ki roto i tētahi kapu ka whakamahana kia tata ki te 80°C. Tauhiuhia mārire, kia ōrite hoki te HPMC ki roto i te kapu ka whakaohokia kia kore ai e piri.
Me whakaoho tonu kia mākū rawa te HPMC, kia marara hoki. Kātahi ka tāpirihia te toenga o te wai matao ka whakamatao ki te pāmahana rūma, kia eke te rōrahi katoa ki te 100 mL.
Whakamātaohia te otinga i te 4°C i te pō kia pupuhi katoa ai, kia whakakorea ai hoki ngā mirumiru hau.
3.4. Te Ine i te Matatini
Whakawhitihia te otinga ki roto i te kaukau wai pāmahana pumau, kia mau tonu te pāmahana ki te 20 ± 0.1°C. Tīpakohia he miro e tika ana (ko te Nama 2, ko te Nama 3 rānei te tikanga) me te tere (ko te tikanga 30 rpm).
Tīmatahia te inenga wai, ka tuhia te pānui ina tau te ngira. Whakahoutia ia inenga kia toru ngā wā, ā, ko te toharite te hua whakamutunga.
Mena ka nui ake te pānui i te awhe o te taputapu, whakakapia te poupou, whakarerekētia rānei te kukū ka ine anō.
4. Ngā Whakatūpato
He mea tino nui te whakahaere i te pāmahana. Mō ia pikinga o te pāmahana 1°C, ka heke te matotoru mā te 2% ki te 3%.
Me rewa katoa te otinga, ā, me kore he mirumiru, ki te kore ka iti, ka rerekē rānei te ine.
He āhuatanga whakaiti-kutikuti tō te HPMC, nō reira me pupuri tonu te tere me te wā ine.
Me kore he poke, he katote rānei i roto i te wai e whakamahia ana kia kore ai e pāngia te whakarewanga me ngā pānui.
Me whakatikatika i te taputapu i ia wā, ā, me pupuri kia ma te poupou me te ipu tauira.
5. Te Tātari i ngā Take Whakaawe
Te Tohu o te Whakapūhui me te Tohu o te Whakakapinga: Ko te teitei ake o te tohu o te whakapūhui o te HPMC, ko te roa ake o te mekameka ngota ngota, ā, ko te nui ake o te matotoru o te otinga. Ka pā anō hoki te tohu o te whakakapinga methoxy me te hydroxypropoxy ki tōna waiora me te hanganga o te otinga.
Te Kukū: He hononga taupū te kukū o te otinga me te matotoru, ā, ahakoa ngā panonitanga iti o te kukū ka pā nui ki ngā hua whakamātautau. Te Pāmahana me te pH: Ka whakaitihia te matotoru e te pikinga o te pāmahana, engari he iti noa te pānga o ngā panonitanga pH ki te matotoru o te HPMC nā te mea he etera cellulose kore-ionic.
Te Pakeketanga o te Otinga: Tērā pea ka heke haere te matotoru i muri i te rokiroki roa. E taunakihia ana kia oti te whakamātautau i roto i ngā haora 24 o te whakarite.
6. Te Whakaaturanga me te Whakamahinga o ngā Hua
Ka whakaatuhia ngā hua whakamātautau i roto i te mPa·s (milliPascals·s), hei tauira, "2% otinga, 20°C, 20,000 mPa·s." I roto i ngā tono ahumahi,HPMCKo ngā tohu matotoru e whakaatuhia ana i roto i ngā haumano, pērā i te 400 cps me te 20,000 cps. Ka taea e ngā kaiwhakamahi te whiriwhiri i ngā tohu rerekē i runga i ngā whakaritenga tono me te hoahoa whakatakotoranga.
Wā tuku: Hurae-30-2025