Inkampani ye-Tiantai Cellulose igxile ocwaningweni, ekuthuthukisweni, ekukhiqizweni nasekukhuthazeni ukuthengiswa kwemikhiqizo ye-hydroxypropyl methyl cellulose ye-HPMC. Ubumsulwa be-HPMC hydroxypropyl methyl cellulose yisihloko somkhiqizo esibaluleke kakhulu kubakhiqizi nabasebenzisi. Lapha sihlinzeka ngesethulo esinemininingwane, ngithemba ukufunda ukuze ngisize.
Ukunqunywa kobumsulwa be-HPMC hydroxypropyl methyl cellulose
Isimiso
I-Hydroxypropyl methyl cellulose HPMC ayincibiliki ku-80% ethanol. Ngemva kokuncibilika nokugezwa izikhathi eziningi, i-80% ethanol encibilikiswe kusampula iyahlukaniswa bese isuswa ukuze kutholakale i-hydroxypropyl methyl cellulose HPMC emsulwa.
Ri-eagent
Ngaphandle kokuthi kushiwo ngenye indlela, ama-reagent aqinisekisiwe ukuthi angamanzi ahlanzekile futhi acwengekile noma ahlanjululwe noma amanzi ahlanzekile afanele kuphela okufanele asetshenziswe ekuhlaziyeni.
I-ethanol engu-95% (GB/T 679).
I-ethanol, isisombululo esingu-80%, hlanganisa i-ethanol engu-95% (E.2.1) engu-840mL ngamanzi ku-1L.
I-BMI (GB/T 12591).
Ithuluzi
Amathuluzi ajwayelekile elebhu
Isivuseleli sokushisa esinobuthi obunamandla, ubude benduku yokuxuba cishe buyi-3.5cm.
Isitsha sokuhluza esinobukhulu obungu-40mL, imbobo engu-4.5μm ~ 9μm.
Isitsha sengilazi, esingu-φ10cm, umgodi ophakathi.
I-Beaker, 400mL.
Ibhavu lamanzi elinokushisa okuhlala njalo.
Ihhavini, ingalawula izinga lokushisa ku-105℃±2℃.
Uhlelo
Kala isampula ngokunembile i-3g (enembile kuya ku-0.001g) ibe yi-beaker enesisindo esingaguquki, engeza i-ethanol engu-150mL engu-80% ku-60℃ ~ 65℃, faka induku yamagnetic kuma-stirrer okushisa amagnetic, umboze isitsha esingaphezulu, faka i-thermometer emgodini ophakathi, uvule ama-stirrer okushisa, ulungise isivinini sokuxuba ukuze ugweme ukuchaphaza, bese ugcina izinga lokushisa lingama-60℃ ~ 65℃. Hlanganisa imizuzu eyi-10.
Yeka ukuxubha, faka i-beaker emanzini afudumele angashintshi angu-60℃ ~ 65℃, yima unganyakazi ukuze ulungise izinto ezinganyibiliki, bese uthela uketshezi olungaphezulu ngangokunokwenzeka esitsheni sokuhlunga esiqinile.
Engeza i-ethanol engu-150mL engu-80% ku-60℃ ~ 65℃ ebhekheni, phinda imisebenzi yokuxuba nokuhlunga engenhla, bese ugeza ibhekheni, isitsha sobuso, induku yokuxuba kanye ne-thermometer ngokucophelela nge-ethanol engu-80% ku-60℃ ~ 65℃, ukuze into enganyibiliki idluliselwe ngokuphelele ebhekheni, bese ugeza okuqukethwe yibhekheni. Ukumunca kufanele kusetshenziswe phakathi nalokhu kusebenza futhi ukomiswa kwekhekhe kufanele kugwenywe. Uma izinhlayiya zidlula esihlungini, ukumunca kufanele kwehliswe ijubane.
Qaphela: kufanele kuqinisekiswe ukuthi i-sodium chloride esesibonelweni ihlanzwe ngokuphelele yi-ethanol engu-80%. Uma kudingeka, isisombululo se-silver nitrate esingu-0.1mol/L kanye ne-nitric acid engu-6mol/L zingasetshenziswa ukuhlola ukuthi i-filtrate inama-ion e-chloride yini.
Emazingeni okushisa egumbi, okuqukethwe yi-crucible kwagezwa kabili nge-ethanol engu-95% ku-50mL, kwathi ekugcineni kwagezwa nge-ethyl mi20mL ukuze kugezwe okwesibili. Isikhathi sokuhlunga akufanele sibe side kakhulu. I-crucible yafakwa ebhekheni yashiswa ebhavini lomusi kuze kube yilapho kungatholakali phunga le-ethyl mi.
Qaphela: ukugeza nge-ethyl mi kuyadingeka ukuze kususwe ngokuphelele i-ethanol entweni engancibiliki. Uma i-ethanol ingasuswa ngokuphelele ngaphambi kokuba yomiswe kuhhavini, ukususwa ngokuphelele akunakwenzeka ngesikhathi sokumiswa kuhhavini.
Isitsha sokubilisa kanye nebhekha kwafakwa kuhhavini ku-105℃±2℃ ukuze komiswe amahora ama-2, kwabe sekudluliselwa emshinini wokomisa ukuze kuphole imizuzu engama-30 kwabe sekukalwa, komiswa ihora eli-1 kwabe sekukalwa ukuze kupholiswe kuze kube yilapho ushintsho lwesisindo lungekho ngaphezu kuka-0.003g. Uma kwenzeka ukwanda kwesisindo ngesikhathi sokomiswa ihora eli-1, isisindo esiphansi kakhulu esibonwe sizoba khona.
Imiphumela ibaliwe
Ubumsulwa be-HPMC hydroxypropyl methyl cellulose babalwe njengengxenyana yesisindo P, futhi inani lavezwa njengo-%
I-M1 — isisindo sezinto ezomisiwe ezinganyibiliki, ngamagremu (g);
I-M0 — Isisindo sengxenye yokuhlola, ngamagremu (g);
W0 — Umswakama kanye nokuqukethwe okuguquguqukayo kwesampula, %.
Inani eliphakathi lezibalo lezilinganiso ezimbili ezihambisanayo lincishisiwe libe yiphuzu elilodwa ledesimali njengomphumela wokulinganisa.
Pukuzimisela
Umehluko ophelele phakathi kwezilinganiso ezimbili ezizimele ezitholwe ngaphansi kwezimo zokuphindeka awudluli ku-0.3%, uma nje ungaphezulu kuka-0.3% kungadluli ku-5%.
Isikhathi sokuthunyelwe: Feb-14-2022