Inkampani yeTiantai Cellulose igxile kuphando, uphuhliso, imveliso kunye nokukhuthaza ukuthengiswa kweemveliso ze-hydroxypropyl methyl cellulose ze-HPMC. Ubunyulu be-HPMC hydroxypropyl methyl cellulose yeyona mveliso ixhalatyelweyo kubavelisi kunye nabasebenzisi. Apha sicebisa abavelisi be-hydroxypropyl methyl cellulose ukuba banike intshayelelo eneenkcukacha, ndiyathemba ukuba ndiza kufunda ukuze ndincede.
Ukuqinisekiswa kobunyulu be-HPMC hydroxypropyl methyl cellulose
Umgaqo
I-Hydroxypropyl methyl cellulose HPMC ayinyibiliki kwi-ethanol engama-80%. Emva kokunyibilika nokuhlanjwa amaxesha amaninzi, i-ethanol engama-80% enyibilikisiweyo kwisampuli iyahlulwa ize isuswe ukuze kufunyanwe i-hydroxypropyl methyl cellulose HPMC ecocekileyo.
Riarhente
Ngaphandle kokuba kuchazwe ngenye indlela, kuphela ii-reagents eziqinisekisiweyo ukuba zingamanzi acocekileyo nacocekileyo okanye anyibilikisiweyo okanye angena-ionized okanye amanzi acocekileyo afanayo aza kusetyenziswa kuhlalutyo.
I-ethanol engama-95% (GB/T 679).
I-Ethanol, isisombululo se-80%, xuba i-95% ye-ethanol (E.2.1) 840mL ngamanzi ukuya kwi-1L.
I-BMI (GB/T 12591).
Isixhobo
Izixhobo zelebhu eziqhelekileyo
Isivuseleli sokufudumeza esinemagnethi, ubude bentonga yokuxuba malunga ne-3.5cm.
Isinyibilikisi sokuhluza, i-40mL, umngxuma we-4.5μm ~ 9μm.
Isitya somphezulu weglasi, φ10cm, umngxuma ophakathi.
Ibhiya, 400mL.
Ibhafu yamanzi enobushushu obuqhelekileyo.
I-oven, inokulawula ubushushu kwi-105℃±2℃.
Inkqubo
Linganisa ngokuchanekileyo isampuli ye-3g (echanekileyo ukuya kwi-0.001g) kwi-beaker enobunzima obungaguqukiyo, yongeza i-150mL ye-80% ye-ethanol kwi-60℃ ~ 65℃, faka intonga yemagnethi kwi-magnetic heating stirrers, gquma isitya somphezulu, faka i-thermometer kumngxuma osembindini, vula i-heating stirrers, lungisa isantya sokuxubha ukuze ungatshizi, kwaye ugcine ubushushu bukwi-60℃ ~ 65℃. Xuba imizuzu eli-10.
Yeka ukuxuba, beka ibheki kwindawo yokuhlambela yamanzi enobushushu obungaguqukiyo obuyi-60℃ ~ 65℃, yima ungashukumi ukuze udibanise izinto ezinganyibilikiyo, uze uthulule ulwelo olungaphezulu kangangoko kunokwenzeka kwisitshizi sokucoca esihlala sihleli.
Yongeza i-150mL ye-ethanol engama-80% kwi-60℃ ~ 65℃ kwi-beaker, phinda le misebenzi yokuxuba nokucoca engentla, uze uhlambe i-beaker, isitya somphezulu, intonga yokuxuba kunye ne-thermometer ngononophelo nge-80% ye-ethanol kwi-60℃ ~ 65℃, ukuze into enganyibilikiyo idluliselwe ngokupheleleyo kwi-crucible, kwaye uhlambe umxholo we-crucible. Kufuneka kusetyenziswe ukufunxa ngexesha lo msebenzi kwaye kufuneka kuthintelwe ukomiswa kwekhekhe. Ukuba amasuntswana adlula kwisihluzo, ukufunxa kufuneka kuncitshiswe isantya.
Qaphela: kufuneka kuqinisekiswe ukuba i-sodium chloride kwisampuli ihlanjwe ngokupheleleyo yi-80% ye-ethanol. Ukuba kuyimfuneko, isisombululo se-silver nitrate esingu-0.1mol/L kunye ne-6mol/L nitric acid zingasetyenziswa ukujonga ukuba i-filtrate inazo na ii-ion ze-chloride.
Kubushushu begumbi, umxholo we-crucible uhlanjwe kabini nge-95% ye-ethanol kwi-50mL, kwaye ekugqibeleni nge-ethyl mi20mL ukuze kuhlanjwe okwesibini. Ixesha lokucoca akufuneki libe lide kakhulu. I-crucible ibekwe kwi-beaker kwaye ifudunyezwe kwi-steam bath de kungabikho vumba le-ethyl mi elifunyenweyo.
Qaphela: ukuhlamba nge-ethyl mi kuyimfuneko ukususa ngokupheleleyo i-ethanol kwinto enganyibilikiyo. Ukuba i-ethanol ayisuswanga ngokupheleleyo ngaphambi kokuba yomiswe kwi-oven, ukususwa ngokupheleleyo akunakwenzeka ngexesha lokumiswa kwe-oven.
Isiqhoboshi kunye nebheki zibekwe kwi-oven kwi-105℃±2℃ ukuze zomiswe iiyure ezi-2, emva koko zidluliselwe kwisomisi ukuze ziphole imizuzu engama-30 kwaye zilinganiswe, zomiswe iiyure ezi-1 kwaye zilinganiswe ukuze zipholiswe de utshintsho lobunzima lungadluli kwi-0.003g. Kwimeko yokwanda kobunzima ngexesha lokumiswa kweyure e-1, kuya kulawula ubunzima obuphantsi obubonwayo.
Iziphumo zibaliwe
Ubumsulwa be-HPMC hydroxypropyl methyl cellulose bubalwa njenge-mass fraction P, kwaye ixabiso lichazwe njenge-%
I-M1 — ubunzima bezinto ezomileyo ezinganyibilikiyo, kwiigrama (g);
I-M0 — Ubunzima becandelo lovavanyo, kwiigrama (g);
W0 — Ukufuma kunye nomxholo oguquguqukayo wesampuli, %.
Ixabiso eliphakathi le-arithmetic leemilinganiselo ezimbini ezihambelanayo liyancitshiswa liye kwinqaku elinye ledesimali njengesiphumo sokulinganisa.
Pisigqibo
Umahluko opheleleyo phakathi kwemilinganiselo emibini ezimeleyo efunyenwe phantsi kweemeko zokuphindaphindeka awungaphezulu kwe-0.3%, ukuba nje ngaphezulu kwe-0.3% ayidluli kwi-5%.
Ixesha lokuthumela: Feb-14-2022