Ukhuseleko lwe-HPMC kwizongezo zokutya

1. Isishwankathelo se-HPMC

I-HPMC (iHydroxypropyl Methylcellulose) yi-cellulose derivative efunyenwe ngokuguqulwa kweekhemikhali. Ifunyanwa kwi-cellulose yezityalo zendalo ngokusebenzisa ii-chemical reactions ezifana ne-methylation kunye ne-hydroxypropylation. I-HPMC inokunyibilika kwamanzi kakuhle, ukulungiswa kwe-viscosity, iipropati zokwenza ifilimu kunye nozinzo, ngoko ke isetyenziswa kakhulu kumashishini amaninzi, ngakumbi kwicandelo lokutya, amayeza kunye nezinto zokuthambisa, njengesithambisi, isizinzisi, i-emulsifier kunye ne-gelling agent.

Kwishishini lokutya, i-HPMC idla ngokusetyenziswa njengesithambisi-zinyo, i-gelling agent, i-humectant, i-emulsifier kunye ne-stabilizer. Uluhlu lokusetyenziswa kwayo ekutyeni luquka: isonka, iikeyiki, iibhisikithi, iilekese, i-ayisikhrim, izinongo, iziselo kunye nokutya okunempilo. Isizathu esibalulekileyo sokusetyenziswa kwayo ngokubanzi kukuba i-AnxinCel®HPMC izinzile kakuhle kwiikhemikhali, ayilula ukuyisabela nezinye izithako, kwaye yonakala lula phantsi kweemeko ezifanelekileyo.

2. Uvavanyo lokhuseleko lwe-HPMC

I-HPMC iye yaqatshelwa kwaye yavunywa ziiarhente ezininzi zelizwe nezamazwe ngamazwe ezilawula ukhuseleko lokutya njengesongezelelo sokutya. Ukhuseleko lwayo luvavanywa kakhulu ngezi zinto zilandelayo:

Uphononongo lweTyhefu

Njenge-derivative ye-cellulose, i-HPMC isekelwe kwi-plant cellulose kwaye inetyhefu ephantsi. Ngokwezifundo ezininzi ze-toxicology, ukusetyenziswa kwe-HPMC ekutyeni akubonisi ubuthi obucacileyo okanye obungapheliyo. Uninzi lwezifundo lubonise ukuba i-HPMC ihambelana kakuhle ne-biocompatibility kwaye ayizukubangela iziphumo ezicacileyo zetyhefu emzimbeni womntu. Umzekelo, iziphumo zovavanyo lwe-HPMC lwe-acute toxicity yomlomo kwiimpuku zibonise ukuba akukho mpendulo icacileyo yetyhefu eyenzekileyo kwiidosi eziphezulu (ezidlula ukusetyenziswa kwemihla ngemihla kwezongezo zokutya).

Ukutya okutyiwayo kunye nee-ADI (Ukutya okutyiwayo kwemihla ngemihla okwamkelekileyo)

Ngokutsho kovavanyo lweengcali zokhuseleko lokutya, ukutya okwamkelekileyo kwe-HPMC imihla ngemihla (i-ADI) akuyi kuyonakalisa impilo yabantu ngaphakathi koluhlu olufanelekileyo lokusetyenziswa. IKomiti yeeNgcali zaMazwe ngaMazwe yezoNcedo zokutya (i-JECFA) kunye ne-US Food and Drug Administration (FDA) kunye namanye amaziko aqaphele ukhuseleko lwe-HPMC njengesongezelelo sokutya kwaye amisela imida efanelekileyo yokusetyenziswa kwayo. Kwingxelo yayo yovavanyo, i-JECFA ibonise ukuba i-HPMC ayizange ibonise naziphi na iziphumo ezinobungozi ezicacileyo, kwaye ukusetyenziswa kwayo ekutyeni ngokubanzi kungaphantsi kakhulu kwexabiso elimiselweyo le-ADI, ngoko ke abathengi akufuneki bakhathazeke ngeengozi zayo zempilo.

Iimpendulo ze-allergy kunye neempendulo ezimbi

Njengento yendalo, i-HPMC ayinazo iimpawu zokunganyamezelani kakuhle. Uninzi lwabantu alunazo iimpawu zokunganyamezelani kakuhle kwi-HPMC. Nangona kunjalo, abanye abantu abanobuthathaka banokufumana iimpawu zokunganyamezelani ezincinci ezifana nokurhawuzelela kunye nokuphefumla kancinci xa besitya ukutya okune-HPMC. Ezi ziphumo zihlala zinqabile. Ukuba kuvela ukungakhululeki, kucetyiswa ukuba uyeke ukutya ukutya okune-HPMC kwaye ufune ingcebiso kugqirha oqeqeshiweyo.

Ukusetyenziswa kwexesha elide kunye nempilo yamathumbu

Njengekhompawundi enemolekyuli eninzi, i-AnxinCel®HPMC kunzima ukuyifunxa emzimbeni womntu, kodwa inokudlala indima ethile njengefayibha yokutya emathunjini kwaye ikhuthaze i-intestinal peristalsis. Ke ngoko, ukutya okuphakathi kwe-HPMC kunokuba nefuthe elihle kwimpilo yamathumbu. Umzekelo, ezinye izifundo zibonise ukuba i-HPMC inamandla athile okuphucula i-intestinal peristalsis kunye nokuphelisa ukuqhina. Nangona kunjalo, ukutya i-HPMC ngokugqithisileyo kunokubangela ukungakhululeki kwamathumbu, ukudumba kwesisu, urhudo kunye nezinye iimpawu, ngoko ke umgaqo wokulinganisela kufuneka ulandelwe.

3. Imeko yokuvunywa kwe-HPMC kumazwe ahlukeneyo

iTshayina

E-China, i-HPMC idweliswe njengesongezo sokutya esivumelekileyo, esisetyenziswa kakhulu kwiilekese, izinongo, iziselo, iimveliso zepasta, njl. Ngokwe-“Standard for the Use of Food Additives” (GB 2760-2014), i-HPMC ivunyiwe ukuba isetyenziswe ekutyeni okuthile kwaye inemida engqongqo yokusetyenziswa.

udibano lwaseyurophu

KwiManyano yaseYurophu, i-HPMC ikwaqatshelwa njengesongezo sokutya esikhuselekileyo, esinenombolo ethi E464. Ngokwengxelo yovavanyo lwe-European Food Safety Authority (EFSA), i-HPMC ikhuselekile phantsi kweemeko ezichaziweyo zokusetyenziswa kwaye ayibonisi miphumo mibi kwimpilo yabantu.

Amazwe Amanyene

I-FDA yase-US idwelisa i-HPMC njengento "eyaziwa ngokubanzi njengekhuselekileyo" (GRAS) kwaye ivumela ukusetyenziswa kwayo ekutyeni. I-FDA ayibeki mida ingqongqo yokusetyenziswa kwe-HPMC, kwaye ikakhulu ivavanya ukhuseleko lwayo ngokusekelwe kulwazi lwesayensi olusetyenziswa ngokwenene.

Njengesongezelelo sokutya,I-HPMC ivunyiwe kumazwe amaninzi nakwiindawo kwihlabathi liphela kwaye ithathwa njengekhuselekileyo ngaphakathi koluhlu oluchaziweyo lokusetyenziswa. Ukhuseleko lwayo luqinisekiswe zizifundo ezininzi ezinobungozi kunye neendlela zonyango, kwaye ayibangeli monakalo mkhulu kwimpilo yabantu. Nangona kunjalo, njengazo zonke izongezo zokutya, ukusela i-HPMC kufuneka kulandele umgaqo wokusetyenziswa ngokufanelekileyo kwaye kuphephe ukusela kakhulu. Abantu abane-allergies kufuneka balumke xa besitya ukutya okune-HPMC ukunciphisa ukwenzeka kweempembelelo ezimbi.

I-HPMC sisongezelelo esisetyenziswa kakhulu nesikhuselekileyo kwishishini lokutya, esingabeki mngcipheko mkhulu kwimpilo yoluntu. Ngokuhambela phambili kwesayensi netekhnoloji, uphando kunye nokubekwa kweliso kwe-AnxinCel®HPMC kunokuba nzima ngakumbi kwixesha elizayo ukuqinisekisa ukhuseleko lwayo.