I-Hydroxypropyl methylcellulose (HPMC)Ifilimu isebenza kakuhle kakhulu, kodwa ngenxa yokuba i-HPMC yijeli yobushushu, i-viscosity kubushushu obuphantsi iphantsi kakhulu, nto leyo engayivumeliyo ukugquma (okanye ukucwilisa) nokomisa kubushushu obuphantsi ukulungiselela ifilimu etyiwayo, nto leyo ebangela ukusebenza kakubi kokucubungula; ukongeza, iindleko zayo eziphezulu zithintela ukusetyenziswa kwayo. Isitatshi seHydroxypropyl (HPS) yijeli ebandayo engabizi kakhulu, ukongezwa kwayo kunokunyusa i-viscosity ye-HPMC kubushushu obuphantsi, kuphucule ukusebenza kokucubungula kwe-HPMC, kwaye kunciphise iindleko zemveliso, ngakumbi, i-hydrophilicity efanayo, iiyunithi zeglucose kunye namaqela e-hydroxypropyl zonke zinegalelo ekuphuculeni ukuhambelana kwezi polymer zimbini. Ke ngoko, inkqubo yokuxuba ijeli ebandayo eshushu yalungiswa ngokuxuba i-HPS kunye ne-HPMC, kwaye isiphumo sobushushu kwisakhiwo sejeli senkqubo yokuxuba ijeli ebandayo eshushu ye-HPMC/HPS safundwa ngokucwangcisiweyo ngokusebenzisa i-rheometer kunye neendlela ezincinci zokusasaza i-X-ray. , idityaniswe nempembelelo yeemeko zonyango lobushushu kwisakhiwo se-microstructure kunye neempawu zenkqubo ye-membrane, yaza yakha ubudlelwane phakathi kwesakhiwo se-gel seempawu ze-blend system-membrane structure-membrane phantsi kweemeko zonyango lobushushu.
Iziphumo zibonisa ukuba kubushushu obuphezulu, ijeli eneI-HPMCUmxholo une-modulus ephezulu kunye nokuziphatha okufana nokuqinileyo okubalulekileyo, ulwakhiwo olufana nokuqinileyo lwe-gel scatterers luxinene ngakumbi, kwaye ubungakanani bee-gel aggregates bukhulu; kubushushu obuphantsi, umxholo we-HPS Iisampulu ze-gel eziphezulu zine-modulus ephezulu, ukuziphatha okufana nokuqinileyo okubonakalayo, kunye nolwakhiwo olufana nokuqinileyo lwe-gel scatterers. Kwiisampulu ezine-blending ratio efanayo, ukubaluleka kwe-modulus kunye nokuziphatha okufana nokuqinileyo kunye noxinano lwesakhiwo olufana nokuqinileyo lwee-gels ezilawulwa yi-HPMC kubushushu obuphezulu ziphezulu kunezo zilawulwa yi-HPS kubushushu obuphantsi. Ubushushu bokomisa bunokuchaphazela ulwakhiwo lwe-gel lwenkqubo ngaphambi kokuba yome, kwaye emva koko buchaphazele ulwakhiwo lwe-crystalline kunye nolwakhiwo olungenamofu lwefilimu, kwaye ekugqibeleni bunempembelelo ebalulekileyo kwiimpawu zoomatshini zefilimu, nto leyo ebangela amandla okutsalwa kunye ne-modulus yefilimu yomiswe kubushushu obuphezulu. Iphezulu kunokomileyo kubushushu obuphantsi. Izinga lokupholisa alinampembelelo icacileyo kwisakhiwo se-crystalline senkqubo, kodwa linempembelelo kuxinano lomzimba we-microdomain self-similar wefilimu. Kule nkqubo, uxinano lwesakhiwo esifana nefilimu lunokuchaphazela iimpawu zoomatshini zefilimu. Ukusebenza kwayo kunempembelelo enkulu.
Ngokusekelwe ekulungiseleleni i-membrane exutyiweyo, olu phononongo lufumanise ukuba ukusetyenziswa kwesisombululo se-iodine ukudaya ngokukhetha i-membrane exutyiweyo ye-HPMC/HPS kumise indlela entsha yokujonga ngokucacileyo ukusasazwa kwesigaba kunye notshintsho lwesigaba senkqubo exutyiweyo phantsi kwe-microscope. indlela, enentsingiselo ekhokelayo yendlela yokufunda ukusasazwa kwesigaba seenkqubo zokuxuba ezisekwe kwisitatshi. Ukusebenzisa le ndlela intsha yophando, edityaniswe ne-infrared spectroscopy, i-scanning electron microscopy kunye ne-extensometer, utshintsho lwesigaba, ukuhambelana kunye neepropati zoomatshini zenkqubo zihlalutywe kwaye zafundwa, kwaye ukuhambelana, utshintsho lwesigaba kunye nokubonakala kwefilimu kwakhiwa. Iziphumo zokujonga i-microscope zibonisa ukuba inkqubo idlula kutshintsho lwesigaba xa umlinganiselo we-HPS ungama-50%, kwaye into yokuxubana phakathi kwesigaba ikhona kwifilimu, ebonisa ukuba inkqubo inomlinganiselo othile wokuhambelana; uhlalutyo lwe-infrared, i-thermogravimetric kunye neziphumo ze-SEM ziqinisekisa ngakumbi ukuxubana. Inkqubo inomlinganiselo othile wokuhambelana. I-modulus yefilimu exutyiweyo iyatshintsha xa umxholo we-HPS ungama-50%. XaI-HPSUmxholo ungaphezulu kwe-50%, i-engile yoqhagamshelwano lwesampuli exutyiweyo iyaphambuka kumgca othe tye odibanisa ii-engile zoqhagamshelwano zeesampuli ezicocekileyo, kwaye xa ingaphantsi kwe-50%, iyaphambuka kakubi kulo mgca othe tye. , ezibangelwa ikakhulu kukutshintsha kwesigaba.
Ixesha leposi: Epreli-25-2024