Aha HPMC nke ndị China bụ hydroxypropyl methylcellulose. Ọ bụghị ionic ma a na-ejikarị ya eme ihe dị ka ihe na-ejide mmiri n'ime ihe a gwakọtara agwakọta. Ọ bụ ihe a na-ejikarị eji ihe na-ejide mmiri n'ime ihe a na-akpọ mentor.
Usoro mmepụta nke HPMC bụ ngwaahịa ether nke dabere na polysaccharide nke a na-emepụta site na alkalization na etherification nke eriri owu (ụlọ). Ọ nweghị chajị n'onwe ya, ọ naghị emeghachi omume na ion ndị a na-agbaze n'ime ihe gelling, ọ na-arụkwa ọrụ kwụsiri ike. Ọnụahịa ya dịkwa ala karịa ụdị cellulose ether ndị ọzọ, yabụ a na-ejikarị ya eme ihe na ngwa agha akọrọ.
Ọrụ nke hydroxypropyl methylcellulose: Ọ nwere ike ime ka smati agwakọtara ọhụrụ sie ike ka o wee nwee viscosity mmiri ma gbochie nkewa. (Ịkpụ) Nchekwa mmiri bụkwa ihe kacha mkpa, nke na-enyere aka ịnọgide na-enwe oke mmiri n'ime smati ahụ, nke mere na mgbe e wuru smati ahụ, ihe simenti ahụ nwere oge ka ukwuu iji mee ka mmiri dị ọcha. (Ịdịgide mmiri) O nwere ihe ndị na-abanye n'ikuku, nke nwere ike iweta afụ ikuku dị ka otu na obere iji melite owuwu smati ahụ.
Ka hydroxypropyl methylcellulose ether na-eto nke ọma, otú ahụ ka arụmọrụ ijigide mmiri ka mma. Viscosity bụ ihe dị mkpa maka arụmọrụ HPMC. Ugbu a, ndị nrụpụta HPMC dị iche iche na-eji ụzọ na ngwa dị iche iche atụ viscosity nke HPMC. Ụzọ ndị bụ isi bụ HaakeRotovisko, Hoppler, Ubbelohde na Brookfield.
Maka otu ngwaahịa ahụ, nsonaazụ viscosity nke e ji ụzọ dị iche iche tụọ dị nnọọ iche, ụfọdụ nwekwara ọdịiche okpukpu abụọ. Ya mere, mgbe a na-atụnyere viscosity, a ga-eme ya n'etiti otu ụzọ nnwale ahụ, gụnyere okpomọkụ, rotor, wdg. Banyere nha irighiri ihe, ka obere irighiri ihe ahụ na-adị mma, otú ahụ ka nchekwa mmiri ka mma. Mgbe nnukwu mkpụrụ ndụ cellulose ether batara na mmiri, elu ahụ na-agbaze ozugbo ma mepụta gel iji kechie ihe ahụ iji gbochie mkpụrụ ndụ mmiri ịnọgide na-abanye. Mgbe ụfọdụ, a pụghị ịgbasa ya ma gbazee ya n'otu aka ahụ ọbụlagodi mgbe a kpachara ya ogologo oge, na-emepụta ihe ngwọta flocculent ma ọ bụ agglomeration. Ọ na-emetụta njide mmiri nke cellulose ether nke ukwuu, ịgbazekwa bụ otu n'ime ihe ndị na-eme ka a họrọ cellulose ether.
Ịdị mma bụkwa ihe dị mkpa maka arụmọrụ nke methyl cellulose ether. MC eji eme ihe maka ngwa agha ntụ ntụ akọrọ chọrọ ka ọ bụrụ ntụ ntụ, nwere obere mmiri, ịdị mma ahụ chọkwara ka 20% ~ 60% nke nha ihe ahụ ghara ịdị ihe karịrị 63um. Ịdị mma ahụ na-emetụta ike ịgbaze hydroxypropyl methylcellulose ether. MC dị nkọ na-abụkarị granular, ọ dịkwa mfe ịgbaze na mmiri na-enweghị njikọta, mana ọnụego mgbaze na-adị nwayọ, yabụ ọ dịghị mma maka iji ya na ngwa agha ntụ ntụ akọrọ.
N'ime ngwa agha ntụ ntụ akọrọ, a na-agbasa MC n'etiti ihe ndị e ji simenti mee dịka ngwakọta, ihe na-emeju ihe na simenti, naanị ntụ ntụ zuru oke nwere ike izere agglomeration methyl cellulose ether mgbe a na-agwakọta ya na mmiri. Mgbe etinyere MC na mmiri iji gbazee agglomerates, ọ na-esiri ike ịgbasa ma gbazee. Nchacha siri ike nke MC abụghị naanị ihe na-emebi ihe, kamakwa ọ na-ebelata ike mpaghara nke ngwa agha ahụ. Mgbe etinyere ngwa agha ntụ ntụ akọrọ dị otú ahụ n'ebe buru ibu, ọsọ ọgwụgwọ nke ngwa agha ntụ ntụ akọrọ mpaghara ga-ebelata nke ukwuu, mgbawa ga-apụtakwa n'ihi oge ọgwụgwọ dị iche iche. Maka ngwa agha a fesara nke nwere owuwu igwe, ihe achọrọ maka ịdị mma dị elu n'ihi obere oge ngwakọta. N'ikwu ya n'ozuzu, ka viscosity dị elu, ka mmetụta njide mmiri ka mma. Agbanyeghị, ka viscosity dị elu na ka ibu molekul nke MC dị elu, mbelata kwekọrọ na ya na ịgbaze ga-enwe mmetụta ọjọọ na ike na arụmọrụ owuwu nke ngwa agha ahụ.
Ka viscosity dị elu, otú ahụ ka mmetụta siri ike nke slaịza ahụ na-apụta ìhè, mana ọ bụghị nke nha anya kpọmkwem. Ka viscosity dị elu, otú ahụ ka slaịza mmiri ahụ ga-adịkwu, ya bụ, n'oge a na-arụ ya, a na-egosipụta ya dị ka ịrapara na scraper na nrapara dị elu na substrate ahụ. Mana ọ baghị uru ịbawanye ike nhazi nke slaịza mmiri ahụ n'onwe ya. Nke ahụ bụ, n'oge a na-arụ ya, arụmọrụ mgbochi sag adịghị apụta ìhè. N'ụzọ megidere nke ahụ, ụfọdụ viscosity dị ọkara na obere mana methyl cellulose ethers agbanwere agbanwe nwere arụmọrụ dị mma n'imeziwanye ike nhazi nke slaịza mmiri.
Njide mmiri nke HPMC na-emetụtakwa okpomọkụ ejiri mee ihe, ebe nchekwa mmiri nke methyl cellulose ether na-ebelata ka okpomọkụ na-arị elu. Agbanyeghị, n'ihe eji eme ihe n'ezie, a na-etinyekarị ụrọ ntụ ntụ akọrọ na ihe ndị na-ekpo ọkụ n'oge okpomọkụ dị elu (karịa ogo 40) n'ọtụtụ ebe, dịka ịcha mgbidi mpụta n'okpuru anyanwụ n'oge ọkọchị, nke na-eme ka simenti dị ngwa ngwa na ime ka ájá kpọrọ nkụ sie ike. Mbelata nke ọnụego njide mmiri na-eduga n'inwe mmetụta doro anya na ma ike ịrụ ọrụ ma iguzogide mgbawa na-emetụta, ọ dịkwa oke mkpa ibelata mmetụta nke ihe okpomọkụ n'okpuru ọnọdụ a.
N'akụkụ a, a na-ewere ihe mgbakwunye methyl hydroxyethyl cellulose ether ugbu a dị ka ihe na-ebute ụzọ na mmepe teknụzụ. Ọ bụ ezie na ọnụọgụ methyl hydroxyethyl cellulose na-abawanye (usoro oge okpomọkụ), ike ịrụ ọrụ na iguzogide mgbawa ka enweghị ike izute mkpa ojiji. Site na ọgwụgwọ pụrụ iche na MC, dị ka ịbawanye ogo etherification, wdg., enwere ike idobe mmetụta njigide mmiri na okpomọkụ dị elu, ka o wee nwee ike inye arụmọrụ ka mma n'ọnọdụ siri ike.
Ojiji nke HPMC ekwesịghị ịdị oke elu, ma ọ bụghị ya, ọ ga-eme ka mmiri dị na ngwa agha ahụ dịkwuo elu, ọ ga-arapara na trowel ahụ, oge nhazi ahụ ga-adịkwa ogologo, nke ga-emetụta ike ịrụ ọrụ ya. Ngwaahịa ngwa agha dị iche iche na-eji HPMC nwere viscosities dị iche iche, anaghịkwa eji HPMC viscosity dị elu eme ihe n'ụzọ na-adịghị mma. Ya mere, ọ bụ ezie na ngwaahịa hydroxypropyl methylcellulose dị mma, a na-eto ha mgbe ejiri ha nke ọma. Ịhọrọ HPMC ziri ezi bụ ọrụ bụ isi nke ndị ọrụ ụlọ nyocha ụlọ ọrụ. Ugbu a, ọtụtụ ndị na-ere ahịa na-eme ihe n'ụzọ na-adịghị mma na-agwakọta HPMC, àgwà ya adịghịkwa mma. Mgbe ị na-ahọrọ cellulose ụfọdụ, ụlọ nyocha kwesịrị ịrụ ọrụ dị mma na nnwale ahụ iji hụ na ngwaahịa ngwa agha ahụ kwụsiri ike, echekwala anyaukwu maka ọnụ ala ma kpatara mfu na-enweghị isi.
Oge ozi: Mee-04-2023