Hydroxypropyl Methyl Cellulose (HPMC), wanda kuma aka sani da sunan kasuwanci hypromellose, wani polymer ne na roba wanda aka samo daga cellulose na halitta. Babban tushen cellulose don samar da HPMC yawanci shine ɓangaren itace ko auduga. Tsarin kera ya ƙunshi gyara cellulose ta hanyar sinadarai ta hanyar etherification, yana shigar da ƙungiyoyin hydroxypropyl da methyl akan kashin bayan cellulose.

Samar da HPMC ya ƙunshi matakai da dama:

1. Cirewar Cellulose:
   • Ana samun cellulose daga tushen shuke-shuke, musamman ɓangaren itacen itace ko auduga. Ana cire cellulose ɗin kuma ana tsarkake shi don ya samar da ɓangaren cellulose.
2. Alkalancin:
   • Ana yi wa ɓangaren litattafan cellulose magani da maganin alkaline, yawanci sodium hydroxide (NaOH), don kunna ƙungiyoyin hydroxyl akan sarkar cellulose.
3. Daidaitawar:
   • Etherification shine babban mataki a cikin samar da HPMC. Ana yin amfani da sinadarin alkali mai narkewa tare da propylene oxide (ga ƙungiyoyin hydroxypropyl) da methyl chloride (ga ƙungiyoyin methyl) don gabatar da waɗannan ƙungiyoyin ether a kan kashin bayan cellulose.
4. Tsaftacewa da Wankewa:
   • An yi amfani da cellulose da aka gyara, wanda yanzu ake kira Hydroxypropyl Methyl Cellulose, wajen kawar da duk wani alkaline da ya rage. Sannan a wanke shi sosai domin kawar da datti da sauran abubuwan da suka lalace.
5. Busarwa da Niƙa:
   • Ana busar da cellulose ɗin da aka gyara don cire danshi mai yawa sannan a niƙa shi ya zama foda mai laushi. Ana iya sarrafa girman barbashi bisa ga abin da aka yi niyya.

Samfurin HPMC da aka samu shine foda fari ko fari mai launuka daban-daban na maye gurbin hydroxypropyl da methyl. Takamaiman halayen HPMC, kamar yadda yake narkewa, danko, da sauran halayen aiki, sun dogara ne akan matakin maye gurbin da kuma tsarin ƙera shi.

Yana da mahimmanci a lura cewa HPMC polymer ne mai semi-synthetic, kuma duk da cewa an samo shi ne daga cellulose na halitta, yana fuskantar manyan gyare-gyare na sinadarai yayin aikin ƙera don cimma halayen da ake so don aikace-aikacen masana'antu daban-daban.