Hot-selling hydroxypropyl methyl cellulose phthalate - Pharmaceutical Grade Hydroxypropyl Methylcellulose(HPMC) – Anxin
Hot-selling hydroxypropyl methyl cellulose phthalate - Pharmaceutical Grade Hydroxypropyl Methylcellulose(HPMC) – Anxin Detail:
Product Description
CAS NO.:9004-65-3
Molecular Formula
Hypromellose (Hydroxypropylmethylcellulose: HPMC) substitution type 2910, 2906, 2208 (USP)
Physical Properties
- White or yellowish white powder
- Soluble in mixed organic or aqueous solvent
- Making up transparent film when solvent remove
- No chemical reaction with drug due to its non-ionic property
- Molecular Weight : 10,000 ~ 1,000,000
- Gel point : 40 ~ 90℃
- Auto-ignition Point : 360℃
Hydroxypropyl Methylcellulose (HPMC) Pharmaceutical Grade is Hypromellose pharmaceutical excipient and supplement,which can be used as thickener, dispersant, emulsifier and film-forming agent.
KimaCell Cellulose ether consists of methyl cellulose (USP, EP,BP,CP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, EP,BP,CP) each available in several grades differing in viscosity.HPMC products are derived from natural refined cotton linter and wood pulp, meeting all the requirements of the USP, EP, BP, along with Kosher and Halal Certifications.
In the manufacturing process, highly purified natural cotton is etherified with methyl chloride or with the combination of methyl chloride and propylene oxide to form a water-soluble, non-ionic cellulose ether. No animal resources are used in the production of HPMC.HPMC can be used as a binder for solid dosage forms such as tablets and granules. It also serves a variety of functions, for examples, in enhancing water retention, thickening, acting as a protective colloid due to its surface activity, sustaining release, and film formation.
KimaCell HPMC provides a variety of functions such as water retention, protective colloid, surface activity, sustained release. It is a non-ionic compound resistant to salting out and stable over a wide pH-range. Typical applications of HPMC are binder for solid dosage forms such as tablets and granules or thickener for liquid applications.
Pharma HPMC comes in diverse viscosity ranges from 3 to 200,000 cps, and it can be widely used for tablet coating, granulation, binder, thickener, stabilizer and making vegetable HPMC capsule.
Chemical Specification
|
Hypromellose Specification |
60E
( 2910 ) |
65F
( 2906 ) |
75K
( 2208 ) |
| Gel temperature (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Product Grade
|
Hypromellose Specification |
60E
( 2910 ) |
65F
( 2906 ) |
75K
( 2208 ) |
| Gel temperature (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Application
Pharma Grade HPMC enable the production of controlled-release formulations with the convenience of the most widely used tablet-binding mechanism. Pharma Grade offer good powder flow, content uniformity, and compressibility, making them well suited for direct compression.
| Pharma Excipients Application | Pharma Grade HPMC | Dosage |
| Bulk Laxative | 75K4000,75K100000 | 3-30% |
| Creams, Gels | 60E4000,75K4000 | 1-5% |
| Ophthalmic Preparation | 60E4000 | 01.-0.5% |
| Eye Drops Preparations | 60E4000 | 0.1-0.5% |
| Suspending Agent | 60E4000, 75K4000 | 1-2% |
| Antacids | 60E4000, 75K4000 | 1-2% |
| Tablets Binder | 60E5, 60E15 | 0.5-5% |
| Convention Wet Granulation | 60E5, 60E15 | 2-6% |
| Tablet Coatings | 60E5, 60E15 | 0.5-5% |
| Controlled Release Matrix | 75K100000,75K15000 | 20-55% |
Features and Benefits
- Improves product flow characteristics
- Reduces processing times
- Identical, stable dissolution profiles
- Improves content uniformity
- Reduces production costs
- Retains tensile strength after double compaction (roller compaction) process
Packaging
The standard packing is 25kg/drum
20’FCL: 9 ton with palletized; 10 ton unpalletized.
40’FCL: 18 ton with palletized; 20 ton unpalletized.
Product detail pictures:
Related Product Guide:
Our enterprise since its inception, usually regards product top quality as business life, repeatedly enhance manufacturing technology, make improvements to product excellent and continuously strengthen enterprise total high quality administration, in strict accordance with all the national standard ISO 9001:2000 for Hot-selling hydroxypropyl methyl cellulose phthalate - Pharmaceutical Grade Hydroxypropyl Methylcellulose(HPMC) – Anxin, The product will supply to all over the world, such as: Macedonia, Jordan, Costa Rica, Based on experienced engineers, all orders for drawing-based or sample-based processing are welcomed. We have won a good reputation for outstanding customer service among our overseas customers. We will continue to try the best to offer you good quality products and the best service. We are looking forward to serving you.
By Roland Jacka from Switzerland - 2017.08.21 14:13
On this website, product categories is clear and rich, I can find the product I want very quickly and easily, this is really very good!
By Poppy from Anguilla - 2017.09.09 10:18
