China wholesale hydroxypropyl methylcellulose uses - Pharmaceutical Grade Hydroxypropyl Methylcellulose(HPMC) – Anxin
China wholesale hydroxypropyl methylcellulose uses - Pharmaceutical Grade Hydroxypropyl Methylcellulose(HPMC) – Anxin Detail:
Product Description
Hydroxypropyl Methyl Cellulose(HPMC)
Molecular Formula
Hypromellose (Hydroxypropylmethylcellulose: HPMC) substitution type 2910, 2906, 2208 (USP)
Physical Properties
- White or yellowish white powder
- Soluble in mixed organic or aqueous solvent
- Making up transparent film when solvent remove
- No chemical reaction with drug due to its non-ionic property
- Molecular Weight : 10,000 ~ 1,000,000
- Gel point : 40 ~ 90℃
- Auto-ignition Point : 360℃
Hydroxypropyl Methylcellulose (HPMC) Pharmaceutical Grade is Hypromellose pharmaceutical excipient and supplement,which can be used as thickener, dispersant, emulsifier and film-forming agent.
QualiCell Cellulose ether consists of methyl cellulose (USP, EP,BP,CP) and three substitution types of hydroxypropyl methyl cellulose (hypromellose USP, EP,BP,CP) each available in several grades differing in viscosity.HPMC products are derived from natural refined cotton linter and wood pulp, meeting all the requirements of the USP, EP, BP, along with Kosher and Halal Certifications.
In the manufacturing process, highly purified natural cotton is etherified with methyl chloride or with the combination of methyl chloride and propylene oxide to form a water-soluble, non-ionic cellulose ether. No animal resources are used in the production of HPMC.HPMC can be used as a binder for solid dosage forms such as tablets and granules. It also serves a variety of functions, for examples, in enhancing water retention, thickening, acting as a protective colloid due to its surface activity, sustaining release, and film formation.
QualiCell HPMC provides a variety of functions such as water retention, protective colloid, surface activity, sustained release. It is a non-ionic compound resistant to salting out and stable over a wide pH-range. Typical applications of HPMC are binder for solid dosage forms such as tablets and granules or thickener for liquid applications.
Pharma HPMC comes in diverse viscosity ranges from 3 to 200,000 cps, and it can be widely used for tablet coating, granulation, binder, thickener, stabilizer and making vegetable HPMC capsule.
Chemical Specification
|
Hypromellose Specification |
60E
( 2910 ) |
65F
( 2906 ) |
75K
( 2208 ) |
| Gel temperature (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Product Grade
|
Hypromellose Specification |
60E
( 2910 ) |
65F
( 2906 ) |
75K
( 2208 ) |
| Gel temperature (℃) | 58-64 | 62-68 | 70-90 |
| Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Application
Pharma Grade HPMC enable the production of controlled-release formulations with the convenience of the most widely used tablet-binding mechanism. Pharma Grade offer good powder flow, content uniformity, and compressibility, making them well suited for direct compression.
| Pharma Excipients Application | Pharma Grade HPMC | Dosage |
| Bulk Laxative | 75K4000,75K100000 | 3-30% |
| Creams, Gels | 60E4000,75K4000 | 1-5% |
| Ophthalmic Preparation | 60E4000 | 01.-0.5% |
| Eye Drops Preparations | 60E4000 | 0.1-0.5% |
| Suspending Agent | 60E4000, 75K4000 | 1-2% |
| Antacids | 60E4000, 75K4000 | 1-2% |
| Tablets Binder | 60E5, 60E15 | 0.5-5% |
| Convention Wet Granulation | 60E5, 60E15 | 2-6% |
| Tablet Coatings | 60E5, 60E15 | 0.5-5% |
| Controlled Release Matrix | 75K100000,75K15000 | 20-55% |
Features and Benefits
- Improves product flow characteristics
- Reduces processing times
- Identical, stable dissolution profiles
- Improves content uniformity
- Reduces production costs
- Retains tensile strength after double compaction (roller compaction) process
Packaging
The standard packing is 25kg/drum
20’FCL: 9 ton with palletized; 10 ton unpalletized.
40’FCL: 18 ton with palletized; 20 ton unpalletized.
Product detail pictures:
Related Product Guide:
With advanced technologies and facilities, strict high-quality handle, reasonable rate, superior services and close co-operation with prospects, we are devoted to furnishing the best price for our customers for China wholesale hydroxypropyl methylcellulose uses - Pharmaceutical Grade Hydroxypropyl Methylcellulose(HPMC) – Anxin, The product will supply to all over the world, such as: Kenya, Malaysia, Israel, Our company abides by the management idea of "keep innovation, pursue excellence". On the basis of assuring the advantages of existing merchandise, we continuously strengthen and extend product development. Our company insists on innovation to promote the sustainable development of enterprise, and make us become the domestic high-quality suppliers.
By Eve from South Korea - 2017.11.01 17:04
Managers are visionary, they have the idea of "mutual benefits, continuous improvement and innovation", we have a pleasant conversation and Cooperation.
By Steven from Jordan - 2017.06.19 13:51
