I-Hydroxypropyl methylcellulose (HPMC)iyi-non-ionic cellulose ether esetshenziswa kabanzi ezintweni zokwakha, kwezokwelapha, ekudleni, ezimonyweni nakwezinye izimboni. Izinkomba zobuchwepheshe eziyinhloko ze-HPMC zifaka phakathi izakhiwo zomzimba nezamakhemikhali, ukuncibilika, i-viscosity, izinga lokushintshana, njll.
1. Ukubukeka nezici eziyisisekelo
I-HPMC ivame ukuba yimpuphu emhlophe noma engemhlophe nhlobo, ayinaphunga, ayinambitheki, ayinabo ubuthi, incibilika kahle emanzini futhi izinzile. Ingahlakazeka ngokushesha futhi incibilike emanzini abandayo ukuze yakhe isixazululo se-colloidal esibonakalayo noma esinamafu kancane, futhi ayinakuncibilika kahle ezinyibilikisini eziphilayo.
2. Ukujiya
Ukuqina kungenye yezinkomba zobuchwepheshe ezibaluleke kakhulu ze-HPMC, okunquma ukusebenza kwe-AnxinCel®HPMC ezisetshenzisweni ezahlukene. Ukuqina kwe-HPMC ngokuvamile kulinganiswa njengesixazululo samanzi esingu-2% ku-20°C, kanti ububanzi be-viscosity obuvamile busukela ku-5 mPa·s kuya ku-200,000 mPa·s. Uma i-viscosity iphakeme, kulapho umphumela wokujiya wesisombululo uba namandla khona futhi i-rheology iba ngcono. Uma isetshenziswa ezimbonini ezifana nezokwakha nezokwelapha, ibanga le-viscosity elifanele kufanele likhethwe ngokwezidingo ezithile.
3. Okuqukethwe kwe-Methoxy kanye ne-Hydroxypropoxy
Izakhiwo zamakhemikhali ze-HPMC zinqunywa kakhulu amazinga ayo okufaka esikhundleni se-methoxy (–OCH₃) kanye ne-hydroxypropoxy (–OCH₂CHOHCH₃). I-HPMC enamazinga ahlukene okufaka esikhundleni ibonisa ukuncibilika okuhlukile, umsebenzi wobuso kanye nokushisa kwe-gelation.
Okuqukethwe kwe-Methoxy: Ngokuvamile phakathi kuka-19.0% no-30.0%.
Okuqukethwe kwe-Hydroxypropoxy: Ngokuvamile phakathi kuka-4.0% no-12.0%.
4. Okuqukethwe komswakama
Okuqukethwe komswakama we-HPMC ngokuvamile kulawulwa ku-≤5.0%. Okuqukethwe komswakama okuphezulu kuzothinta ukuzinza kanye nomphumela wokusetshenziswa komkhiqizo.
5. Okuqukethwe Komlotha
Umlotha yinsalela ngemva kokushiswa kwe-HPMC, ikakhulukazi evela kusawoti wezinto ezingaphili osetshenziswa enqubweni yokukhiqiza. Okuqukethwe komlotha kuvame ukulawulwa ku-≤1.0%. Okuqukethwe komlotha okuphezulu kakhulu kungathinta ukucaca kanye nobumsulwa be-HPMC.
6. Ukuncibilika kanye nokucaca
I-HPMC inokuncibilika kahle kwamanzi futhi ingancibilika ngokushesha emanzini abandayo ukuze yakhe isixazululo esifanayo se-colloidal. Ukucaca kwesisombululo kuncike ekuhlanzekeni kwe-HPMC kanye nenqubo yayo yokuncibilika. Isixazululo se-HPMC esisezingeni eliphezulu sivame ukucaca noma sibe nobisi kancane.
7. Izinga lokushisa lejeli
Isixazululo samanzi se-HPMC sizokwakha ijeli ekushiseni okuthile. Izinga lokushisa lejeli laso livame ukuba phakathi kuka-50 no-90°C, kuye ngokuqukethwe kwe-methoxy kanye ne-hydroxypropoxy. I-HPMC enokuqukethwe okuphansi kwe-methoxy inokushisa okuphezulu kwejeli, kuyilapho i-HPMC enokuqukethwe okuphezulu kwe-hydroxypropoxy inokushisa okuphansi kwejeli.
8. Inani le-pH
Inani le-pH lesisombululo samanzi i-AnxinCel®HPMC livame ukuba phakathi kuka-5.0 no-8.0, okuyinto engathathi hlangothi noma e-alkaline kancane futhi efanelekile ezindaweni ezahlukahlukene zokusetshenziswa.
9. Usayizi Wezinhlayiya
Ubuncane be-HPMC buvame ukuvezwa njengephesenti elidlula esikrinini esine-mesh engu-80 noma engu-100. Ngokuvamile kudingeka ukuthi u-≥98% adlule esikrinini esine-mesh engu-80 ukuqinisekisa ukuthi sinokuhlakazeka okuhle kanye nokuncibilika kwayo uma isetshenziswa.
10. Okuqukethwe kwensimbi enamandla
Okuqukethwe kwensimbi esindayo (njenge-lead ne-arsenic) kwe-HPMC kumele kuhambisane nezindinganiso ezifanele zomkhakha. Ngokuvamile, okuqukethwe kwensimbi esindayo kungu-≤10 ppm kanti okuqukethwe kwe-arsenic kungu-≤3 ppm. Ikakhulukazi ku-HPMC yokudla neyemithi, izidingo zokuqukethwe kwensimbi esindayo ziqinile kakhulu.
11. Izinkomba ze-Microbial
Ku-AnxinCel®HPMC yemithi kanye nezinga lokudla, ukungcola kwamagciwane kumele kulawulwe, okuhlanganisa inani lamakholoni, isikhunta, imvubelo, i-E. coli, njll., ngokuvamile okudinga:
Inani eliphelele lekholoni ≤1000 CFU/g
Inani eliphelele lesikhunta kanye nenani lemvubelo ≤100 CFU/g
I-E. coli, i-Salmonella, njll. akumele itholakale
12. Izindawo eziyinhloko zokusetshenziswa
I-HPMC isetshenziswa kabanzi ezimbonini eziningi ngenxa yokuqina kwayo, ukugcinwa kwamanzi, ukwakha ifilimu, ukuthambisa, ukuhlanganisa kanye nezinye izakhiwo:
Imboni yokwakha: Njengesithako sokujiya kanye ne-ejenti yokugcina amanzi ku-samente mortar, i-putty powder, i-tile adhesive, kanye ne-waterproof coating ukuthuthukisa ukusebenza kokwakha.
Imboni yezemithi: Isetshenziswa njenge-glue, into ekhishwa njalo, kanye ne-capsule shell eluhlaza yamaphilisi emithi.
Imboni yokudla: esetshenziswa njenge-emulsifier, i-stabilizer, i-thickener, esetshenziswa ku-jelly, iziphuzo, izimpahla ezibhakiwe, njll.
Imboni yamakhemikhali yansuku zonke: isetshenziswa njengesithambisi-zinzisi kanye nesithambisi-zinzisi emikhiqizweni yokunakekelwa kwesikhumba, izihlanzi, kanye nama-shampoo.
Izinkomba zobuchwepheshe zeI-HPMCfaka i-viscosity, izinga lokushintsha (okuqukethwe kweqembu elifakwe i-hydrolyzed), umswakama, okuqukethwe komlotha, inani le-pH, izinga lokushisa lejeli, ubuncane, okuqukethwe kwensimbi esindayo, njll. Lezi zinkomba zinquma ukusebenza kwayo kokusetshenziswa emikhakheni ehlukene. Lapho bekhetha i-HPMC, abasebenzisi kufanele banqume imininingwane efanele ngokuya ngezidingo ezithile zokusetshenziswa ukuqinisekisa umphumela omuhle kakhulu wokusetshenziswa.
Isikhathi sokuthunyelwe: Feb-11-2025