Hydroxypropyl methylcellulose (HPMC)imhando ye ether isina ionic cellulose inoshandiswa zvakanyanya muzvinhu zvekuvaka, mishonga, chikafu, zvizoro nedzimwe nzvimbo. Zviratidzo zvikuru zvehunyanzvi zveHPMC zvinosanganisira hunhu hwemuviri nemakemikari, kunyungudika, viscosity, mwero wekutsiva, nezvimwewo.
1. Chitarisiko uye hunhu hwepakutanga
HPMC inowanzova upfu huchena kana husina kuchena, husina hwema, husina kunaka, husina chepfu, hune mvura inonyunguduka zvakanaka uye hunogara zvakanaka. Hunogona kupararira nekunyunguduka mumvura inotonhora kuti hugadzire colloidal solution yakajeka kana kuti ine madhaka mashoma, uye hahuna kunyunguduka kwakawanda mu organic solvents.
2. Kusviba
Kusimba kwesimba ndeimwe yezviratidzo zvakakosha zveHPMC, izvo zvinosarudza mashandiro eAnxinCel®HPMC mumashandisirwo akasiyana. Kusimba kwesimba reHPMC kunowanzo kuyerwa se2% mvura inodziya pa20°C, uye huwandu hwesimba resimba hunobva pa5 mPa·s kusvika 200,000 mPa·s. Kusimba kwesimba resimba remvura kunowedzera simba resimba remvura uye rheology inowedzera kunaka. Kana ikashandiswa mumaindasitiri akadai sekuvaka nemishonga, giredhi resimba rakakodzera rinofanira kusarudzwa zvichienderana nezvinodiwa chaizvo.
3. Zviri Mukati meMethoxy neHydroxypropoxy
Hunhu hwemakemikari eHPMC hunonyanya kutsanangurwa nemadhigirii ayo ekutsiva emethoxy (–OCH₃) uye hydroxypropoxy (–OCH₂CHOHCH₃). HPMC ine madhigirii akasiyana ekutsiva inoratidza kunyungudika kwakasiyana, kushanda kwepamusoro uye tembiricha yegelation.
Zviri mukati meMethoxy: Kazhinji pakati pe19.0% ne30.0%.
Zviri mukati meHydroxypropoxy: Kazhinji pakati pe4.0% ne12.0%.
4. Hunyoro
Hunyoro hweHPMC hunowanzo dzora hunyoro pa ≤5.0%. Hunyoro hwakawanda hunokanganisa kugadzikana uye kushanda kwechigadzirwa.
5. Zviri Mudota
Dota ndiro rasara mushure mekupiswa kweHPMC, kunyanya kubva mumunyu usingashandiswi mukugadzirwa. Dota rakawanda rinowanzo dzorwa pa ≤1.0%. Dota rakawandisa rinogona kukanganisa kujeka uye kuchena kweHPMC.
6. Kunyungudika uye kujeka
HPMC inonyungudika zvakanaka mumvura uye inogona kunyungudika nekukurumidza mumvura inotonhora kuti igadzire mhinduro yakafanana yecolloidal. Kujeka kwemushonga kunoenderana nekuchena kweHPMC uye maitiro ayo ekunyungudika. Mushonga weHPMC wemhando yepamusoro unowanzo penya kana kuti une mukaka zvishoma.
7. Kupisa kweGel
Mvura inobuda muHPMC inoumba gel patembiricha yakati. Tembiricha yayo yegel inowanzova pakati pe50 ne90°C, zvichienderana nehuwandu hwemethoxy nehydroxypropoxy. HPMC ine methoxy yakaderera ine tembiricha yepamusoro yegel, nepo HPMC ine hydroxypropoxy yakawanda ine tembiricha yakaderera yegel.
8. kukosha kwepH
pH yeAnxinCel®HPMC mvura inowanzova pakati pe5.0 ne8.0, iyo isina neutral kana kuti isina alkaline uye yakakodzera nzvimbo dzakasiyana-siyana dzekushandisa.
9. Saizi yezvikamu
Kupfava kweHPMC kunowanzo ratidzwa sehuwandu hunopfuura nepachiratidziro che 80-mesh kana 100-mesh. Kazhinji zvinodikanwa kuti ≥98% ipfuure nepachiratidziro che 80-mesh kuti ive nechokwadi chekuti inopararira zvakanaka uye inonyunguduka kana ichishandiswa.
10. Zviri musimbi ine simba
Kuwanda kwesimbi inorema (senge lead nearsenic) yeHPMC kunofanirwa kutevedzera mitemo yeindasitiri. Kazhinji, huwandu hwesimbi inorema hunosvika ≤10 ppm uye huwandu hwearsenic hunosvika ≤3 ppm. Kunyanya muHPMC yechikafu neyemishonga, zvinodiwa kuti simbi inorema ive yakaoma zvakanyanya.
11. Zviratidzo zvehutachiona
PaAnxinCel®HPMC yemishonga neyemhando yechikafu, kusvibiswa kwehutachiona kunofanirwa kudzorwa, kusanganisira huwandu hwese hwemakoloni, chakuvhuvhu, mbiriso, E. coli, nezvimwewo, zvinowanzo dikanwa:
Huwandu hwese hwemakoroni ≤1000 CFU/g
Huwandu hwese hwechiumbwa nembiriso ≤100 CFU/g
E. coli, Salmonella, nezvimwewo hazvifanirwe kuonekwa
12. Nzvimbo huru dzekushandisa
HPMC inoshandiswa zvakanyanya mumaindasitiri mazhinji nekuda kwekukora kwayo, kuchengetedza mvura, kugadzira firimu, kunyorovesa, emulsification nezvimwe zvinhu:
Indasitiri yekuvaka: Sechinhu chinosimbisa uye chinochengetedza mvura mumota yesimende, upfu hweputty, chinamira chemataira, uye chinodzivirira mvura kuti zvivandudze mashandiro ekuvaka.
Indasitiri yemishonga: Inoshandiswa sechinonamira, chinhu chinogara kwenguva refu, uye sechinhu chisina kubikwa che capsule shell chekushandisa mapiritsi emishonga.
Indasitiri yechikafu: inoshandiswa se emulsifier, stabilizer, thickener, inoshandiswa mujeli, zvinwiwa, zvinhu zvakabikwa, nezvimwewo.
Indasitiri yemakemikari yezuva nezuva: inoshandiswa sechinosimbisa uye chinosimbisa ganda muzvigadzirwa zvekuchengetedza ganda, sipo, uye shampoo.
Zviratidzo zvehunyanzvi zveHPMCzvinosanganisira viscosity, mwero wekutsiva (hydrolyzed group content), hunyoro, dota content, pH value, gel tembiricha, fineness, heavy metal content, nezvimwewo. Izvi zvinoratidza mashandiro ayo muminda yakasiyana. Pakusarudza HPMC, vashandisi vanofanira kusarudza zvinodiwa zvakakodzera zvichienderana nezvinodiwa zvekushandisa kuti vave nechokwadi chekuti zvakanakisa pakushandisa.
Nguva yekutumira: Kukadzi-11-2025