Mushonga Unobatsira
Hydroxypropyl methylcellulose (HPMC) ichena kana kuti chena yakaita semukaka, haina hwema, haina kunaka, ine upfu hwe fibrous kana granule, kudzikira kwehuremu pakuomeswa hakupfuuri 10%, inonyungudika mumvura inotonhora asi kwete mumvura inopisa, zvishoma nezvishoma mumvura inopisa. Kuzvimba, peptization, uye kugadzira mhinduro ye colloidal ine viscous, iyo inova mhinduro kana yatonhodzwa, uye inova gel kana yapiswa. HPMC hainyungudike mu ethanol, chloroform uye ether. Inonyungudika mu solvent yakasanganiswa ye methanol ne methyl chloride. Inonyungudikawo mu solvent yakasanganiswa ye acetone, methyl chloride ne isopropanol nedzimwe organic solvents. Mhinduro yayo yemvura inogona kutsungirira munyu (solution yayo ye colloidal haiparadzwe nemunyu), uye pH ye 1% aqueous solution ndeye 6-8. Fomura ye HPMC ndeye C8H15O8-(C10H18O6) -C815O, uye huwandu hwemamorekuru hunosvika 86,000.
HPMC ine mvura inonyungudika zvakanaka mumvura inotonhora. Inogona kunyungudutswa kuita mhinduro yakajeka nekuisanganisa zvishoma mumvura inotonhora. Kusiyana neizvi, hainyunguduke mumvura inopisa iri pamusoro pe60℃ uye inogona kuzvimba chete. I non-ionic cellulose ether. Mhinduro yayo haina ionic charge, haisangani nemetal salts kana ionic organic compounds, uye haisangani nezvimwe zvinhu zvisina kugayiwa panguva yekugadzirira; ine simba rakasimba rekudzivirira allergy, uye nekuwedzera kwedanho rekutsiva muchimiro chemamorekuru, inodzivirira allergies uye yakagadzikana; hainawo metabolic inert. Semubatsiri wemishonga, haigayiwe kana kunyudzwa. Saka, haipe macalorie mumishonga nezvikafu. Haina macalorie akaderera, haina munyu, uye haina munyu kune varwere vane chirwere cheshuga. Mishonga nezvikafu zvine allergy zvine simba rayo; yakagadzikana kune acids nealkalis, asi kana PH value ikadarika 2~11 uye ikakanganiswa nekupisa kwakanyanya kana kuti iine nguva yakareba yekuchengetedza, viscosity yayo ichaderera; Mhinduro yayo yemvura inogona kupa basa repamusoro, ichiratidza kushushikana kuri pakati nepakati uye kushushikana kwepakati pechiso; ine emulsification inoshanda muchimiro chezvikamu zviviri, inogona kushandiswa se stabilizer inoshanda uye colloid inodzivirira; mhinduro yayo yemvura ine hunhu hwakanaka hwekugadzira firimu, ipiritsi uye piritsi. Kuputira firimu kwakagadzirwa nayo kune zvakanakira kusava neruvara uye kuomarara. Kuwedzera glycerin kunogonawo kuvandudza plasticity yayo.
Zvigadzirwa zveAnxinCel® HPMC zvinogona kuvandudzwa nezviratidzo zvinotevera muPharmaceutical Excipient:
·Kana yangonyungudika mumvura uye yashanduka kuita chando kuburikidza nechinonyungudutsa, HPMC inogadzira firimu rinoonekera rine simba guru rekudhonza.
·Inowedzera simba rekubatanidza.
·Hydrophilic matrix inoshandiswa pamwe chete neHPMC hydrates kugadzira gel layer, ichidzora maitiro ekuburitswa kwemishonga.
| Giredhi Rinokurudzira: | Kumbira TDS |
| HPMC 60AX5 | Dzvanya pano |
| HPMC 60AX15 | Dzvanya pano |