I tēnei wā, ko te nuinga o ngā rauemi mata o ngā kāpū tipu ko te hydroxypropyl methylcellulose (HPMC) me te pullulan, ā, e whakamahia ana hoki te māngaro hydroxypropyl hei rauemi mata.
Mai i te tīmatanga o te tekau tau atu i 2010,HPMCkua whakamahia i roto i te umanga hanga kāpūru tipu Hainamana, ā, nā runga i tana mahi pai, kua mau te tūranga o ngā kāpūru kau o HPMC i roto i te mākete kāpūru, e whakaatu ana i te pikinga kaha o te tono i roto i te tekau tau kua hipa.
E ai ki ngā raraunga ahumahi, i te tau 2020, ko te nui o ngā hoko ā-rohe o ngā kāpūre mārō tuwhera ka tata ki te 200 piriona kāpūre (ko ngā ahumahi rongoā me ngā hua hauora te whakakotahi), ā, ko te nui o ngā hoko o ngā kāpūre HPMC ka tata ki te 11.3 piriona kāpūre (tae atu ki ngā kaweake), he pikinga 4.2% mai i te tau 2019. %, e 5.5% pea. Ko te ahumahi kore-rongoā te 93.0% o te kai o ngā kāpūre HPMC i Haina, ā, ko te tipu o te ahumahi hua hauora te mea e akiaki ana i ngā hoko o ngā kāpūre HPMC.
Mai i te tau 2020 ki te tau 2025, e matapaetia ana ko te CAGR o ngā kāpū HPMC me ngā kaihoko whakapūkara he 6.7%, he teitei ake tēnei i te tere tipu o te 3.8% mō ngā kāpū gelatin. Heoi anō, ko te hiahia mō ngā kāpū HPMC i roto i te umanga hua hauora ā-rohe he teitei ake i tērā i roto i te umanga rongoā.HPMCKa taea e ngā kāpūru te āwhina i ngā wero rongoā, me te whakatutuki hoki i ngā hiahia ahurea me ngā hiahia kai a ngā kaihoko huri noa i te ao. Ahakoa he iti iho tonu te hiahia o nāianei mō ngā kāpūru HPMC i ērā o ngā kāpūru tine, he teitei ake te tere tipu o te hiahia i ērā o ngā kāpūru tine.
1) Te whakatakotoranga me te tukanga hou, kāore he kaihoko whakapūkara; he pai ake te wairewa, he rite tonu te whanonga waimeha i roto i ngā momo pāpāho, kāore e pāngia e te pH me te kaha ionic, ā, e tutuki ana i ngā whakaritenga pharmacopoeia o ngā whenua me ngā rohe nui;
2) Mō ngā ihirangi kawakore ngoikore, whakapai ake i te wātea o te koiora me te whakapai ake i te arotautanga o te puka horopeta;
3) He ataahua te āhua, ā, he nui ake ngā tae e taea te whiriwhiri.
Ko te kāpū ngohengohe he whakaritenga i hangaia mā te hiri i te hinu, i te whakatārewatanga rānei i roto i te anga kāpū, ā, he porowhita tōna āhua, he āhua oriwa, he āhua ika iti, he āhua maturuturu, me ētahi atu. Ko tōna āhuatanga ko te whakarewa, te whakatarewa rānei i ngā kai mahi ki roto i te hinu, he tere ake te mahi me te nui o te bioavailability i te hanga i te kai mahi kotahi ki roto i ngā papa, ā, kua whānuitia te whakamahinga i roto i te whakarite i ngā hua hauora me ngā rongoā. I ēnei rā, kei te mākete kē ngā kāpū ngohengohe me ngā āhuatanga rerekē pērā i te paninga-enteric, te ngaungau, te papu osmotic, te tuku-roa, me ngā suppositories ngohengohe. Ko te anga kāpū ngohengohe he mea tito mai i ngā tāpiringa colloid me ngā tāpiringa āwhina. I roto i ēnei, ko ngā colloid pērā i te gelatin, te kapia huawhenua rānei ngā wāhanga matua, ā, ko tōna kounga ka pā tika ki te mahi a ngā kāpū ngohengohe. Hei tauira, ka puta te turuturu o te anga kāpū, te piri, te hekenga rauemi, te puhoi o te pakaru, me te whakarewatanga o ngā kāpū ngohengohe i te wā rokiroki. Ko ngā raruraru pērā i te kore tutuki i ngā whakaritenga e pā ana ki tēnei.
I tēnei wā, ko te nuinga o ngā rauemi kāpū o ngā kāpū ngohengohe rongoā i tōku whenua he tiēra kararehe, engari nā te whanaketanga hohonu me te whakamahinga o ngā kāpū ngohengohe tiēra, kua kitea nuitia ōna ngoikoretanga me ōna ngoikoretanga, pērā i te uaua o ngā puna rauemi mata, me te ngāwari o te tauhohenga hononga-hono ki ngā matū aldehyde. Ko ngā raruraru kounga pērā i te wā rokiroki poto me ngā "para e toru" i puta i roto i te tukanga whakamahine tiēra he nui ake te pānga ki te tiaki taiao. Hei tāpiri, kei reira anō te raruraru o te whakapakeketanga i te takurua, he pānga kino ki te kounga o te whakaritenga. Ā, he iti ake te pānga o ngā kāpū ngohengohe kāpia huawhenua ki te taiao e karapoti ana. Nā te pakarutanga o ngā mate pipiri o te kararehe puta noa i te ao, kei te piki haere te āwangawanga o te ao mō te haumaru o ngā hua kararehe. Ki te whakatauritea ki ngā kāpū tiēra kararehe, he pai ngā painga o ngā kāpū tipu i runga i te whakamahinga, te haumaru, te pumau, me te tiaki taiao.
Tāpirihydroxypropyl methylcelluloseki te wai, ka horahia kia puta ai te wairewa A; tāpirihia te kaitao, te mea whakakōkī, te mea whakapūmau, te mea whakamātao me te tae ki te wai, ka horahia kia puta ai te wairewa B; whakaranua ngā wairewa A me B, ka whakamahana ki te 90 ~95°C, ka whakaoho, ka pupuri kia mahana mō te 0.5~2 hāora, ka whakamatao ki te 55~70°C, ka pupuri kia mahana, ka waiho kia memeha te huka kia puta ai te kāpia;
Me pēhea te tere o te tiki i te wai kāpia, ko te tukanga whānui ko te whakamahana mārire i roto i te ipu wai mō te wā roa,
Ka tere te tuku a ētahi kaihanga i te mira colloid mā te kāpia matū.
Wā tuku: Paenga-whāwhā-25-2024