1. I-Crosscarmellose sodium(i-CMCNa edityanisiweyo): i-copolymer edityanisiweyo ye-CMCNa
Iimpawu: Umgubo omhlophe okanye omhlophe. Ngenxa yesakhiwo esidityanisiweyo, awunyibiliki emanzini; uvuvukala ngokukhawuleza emanzini ukuya kuthi ga kwi-4-8 yomthamo wawo wokuqala. Umgubo uthambile kakuhle.
Ukusetyenziswa: Yeyona isetyenziswa kakhulu yi-super disintegrant. I-Disintegrant kwiipilisi eziselwayo, iikhaphukhaphu, iigranules.
2. I-Carmelose calcium (i-CMCCa edityanisiweyo):
Iipropati: Umhlophe, umgubo ongenavumba, i-hygroscopic. Isisombululo se-1% pH 4.5-6. Phantse ayinyibiliki kwi-ethanol kunye ne-ether solvent, ayinyibiliki emanzini, ayinyibiliki kwi-hydrochloric acid enyibilikisiweyo, inyibilika kancinci kwi-alkali enyibilikisiweyo. okanye umgubo ongekho mhlophe. Ngenxa yesakhiwo esidityanisiweyo, ayinyibiliki emanzini; iyadumba xa ifunxa amanzi.
Ukusetyenziswa: ithebhulethi eqhekekileyo, i-binder, i-diluent.
3. I-Methylcellulose (MC):
Ulwakhiwo: i-methyl ether ye-cellulose
Iipropati: Umgubo omhlophe ukuya kotyheli omhlophe okanye iigranule. Ayinyibiliki emanzini ashushu, isisombululo setyuwa eyomileyo, utywala, i-ether, i-acetone, i-toluene, i-chloroform; iyanyibilika kwi-glacial acetic acid okanye umxube olinganayo wotywala kunye ne-chloroform. Ukunyibilika emanzini abandayo kunxulumene nomlinganiselo wokutshintshwa, kwaye iyanyibilika kakhulu xa umlinganiselo wokutshintshwa uyi-2.
Ukusetyenziswa: i-tablet binder, i-matrix ye-tablet disintegrating agent okanye i-sustained-release preparation, i-cream okanye i-gel, i-suspending agent kunye ne-thickening agent, i-tablet coating, i-emulsion stabilizer.
4. I-ethyl cellulose (EC):
Ulwakhiwo: I-ethyl ether ye-cellulose
Iimpawu: Umgubo omhlophe okanye otyheli-mhlophe kunye neegranules. Ayinyibiliki emanzini, ulwelo lwesisu, iglycerol kunye nepropylene glycol. Inyibilika lula kwi-chloroform kunye ne-toluene, kwaye yenza i-white precipitate xa kukho i-ethanol.
Ukusetyenziswa: Yinto efanelekileyo yokuthwala enganyibilikiyo emanzini, efanelekileyo njenge-matrix yamayeza angenamanzi, i-carrier enganyibilikiyo emanzini, i-tablet binder, i-film material, i-microcapsule material kunye ne-sustainable-release coating material, njl.
5. I-Hydroxyethyl Cellulose (HEC):
Ulwakhiwo: I-ether ye-hydroxyethyl engaphelelanga ye-cellulose.
Iipropati: Umgubo otyheli okanye omhlophe ofana nobisi. Unyibilika ngokupheleleyo emanzini abandayo, emanzini ashushu, i-asidi ebuthathaka, isiseko esibuthathaka, i-asidi enamandla, isiseko esomeleleyo, onganyibilikiyo kwiintlaka ezininzi ze-organic (enyibilikayo kwi-dimethyl sulfoxide, i-dimethylformamide), kwiintlaka ze-diol polar organic. Inganda okanye inyibilike kancinci.
Izicelo: Izixhobo zepolymer ezingenakunyibilika emanzini; izithambisi zokulungiselela amehlo, i-otology kunye nokusetyenziswa kwesikhumba; i-HEC kwizithambisi zamehlo omileyo, iilensi zoqhagamshelwano kunye nomlomo owomileyo; isetyenziswa kwizinto zokuthambisa. Njenge-binder, i-arhente yokwenza ifilimu, i-arhente yokuqina, i-arhente yokumisa kunye ne-stabilizer yamayeza nokutya, inokuyigquma amasuntswana amayeza, ukuze amasuntswana amayeza adlale indima yokukhulula kancinci.
6. I-Hydroxypropyl Cellulose (HPC):
Ulwakhiwo: I-ether ye-polyhydroxypropyl ether engaphelelanga ye-cellulose
Iipropati: I-HPC ethathelwe indawo ephezulu ngumgubo omhlophe okanye otyheli kancinci. Inyibilika kwi-methanol, i-ethanol, i-propylene glycol, i-isopropanol, i-dimethyl sulfoxide kunye ne-dimethyl formamide, uhlobo oluphezulu lwe-viscosity alunyibiliki kangako. Ayinyibiliki emanzini ashushu, kodwa inokudumba. I-Thermal gelation: inyibilika lula emanzini angaphantsi kwama-38°C, i-gelatinized ngokufudumeza, kwaye yenze ukudumba okuthambileyo kuma-40-45°C, okunokufunyanwa ngokuphola.
Iimpawu ezibalaseleyo ze-L-HPC: ezinganyibilikiyo emanzini nakwizinto eziphilayo, kodwa ziyadumba emanzini, kwaye ipropati yokudumba iyanda ngokwanda kwezinto ezithatha indawo yazo.
Ukusetyenziswa: I-HPC ethathelwe indawo ephezulu isetyenziswa njengesixhobo sokubopha iipilisi, i-granulating agent, izinto zokugquma iifilimu, kwaye ingasetyenziswa njengezinto zefilimu ezifakwe kwiiplastiki ezincinci, izinto ze-matrix kunye nezinto ezincedisayo zepilisi yokugcina isisu, i-thickener kunye ne-Protective colloids, ezisetyenziswa rhoqo kwiipatches ze-transdermal.
I-L-HPC: Isetyenziswa kakhulu njenge-tablet disintegrant okanye i-binder ye-wet granulation, njenge-tablet-release matrix ehlala ihleli, njl.njl.
7. I-Hypromellose (HPMC):
Ulwakhiwo: I-methyl engaphelelanga kunye ne-polyhydroxypropyl ether ye-cellulose
Iipropati: Umgubo omhlophe okanye ongekho mhlophe okanye onamaqhekeza. Unyibilika emanzini abandayo, awunyibiliki emanzini ashushu, kwaye uneempawu zokufudumala. Unyibilika kwizisombululo ze-methanol kunye ne-ethanol, ii-hydrocarbons ze-chlorine, i-acetone, njl. Ukunyibilika kwayo kwi-organic solvents kungcono kune-water soluble.
Indlela esetyenziswa ngayo: Le mveliso sisisombululo samanzi esinobumanzi obuphantsi esisetyenziswa njengezinto zokugquma ifilimu; isisombululo se-organic solvent esinobumanzi obuphezulu sisetyenziswa njengesixhobo sokubopha iipilisi, kwaye imveliso enobumanzi obuphezulu ingasetyenziselwa ukuthintela ukukhululwa kwamayeza anyibilikayo emanzini; njengesixhobo sokutyebisa amaconsi amehlo kwi-lacquer kunye ne-artificial tears, kunye ne-agent yokumanzisa kwiilensi zoqhagamshelwano.
8. I-Hypromellose Phthalate (HPMCP):
Ulwakhiwo: I-HPMCP yi-phthalic acid i-half ester ye-HPMC.
Iimpawu: Iiflakes okanye iigranules ezibengezelayo okanye ezimhlophe. Ezinganyibilikiyo emanzini nakwisisombululo se-asidi, azinyibilikiyo kwi-hexane, kodwa zinyibilikayo lula kumxube we-acetone:methanol, i-acetone:ethanol okanye i-methanol:chloromethane.
Ukusetyenziswa: Uhlobo olutsha lwezinto zokugquma ezinentsebenzo egqwesileyo, ezinokusetyenziswa njengengubo yefilimu ukufihla ivumba elingaqhelekanga leepilisi okanye iigranules.
9. I-Hypromellose Acetate Succinate (HPMCAS):
Ulwakhiwo: Ii-ester ezixutyiweyo ze-acetic kunye ne-succinic zeI-HPMC
Iipropati: Umgubo omhlophe ukuya kotyheli omhlophe okanye iigranules. Inyibilika kwisisombululo se-sodium hydroxide kunye ne-sodium carbonate, inyibilika lula kwi-acetone, i-methanol okanye i-ethanol: amanzi, umxube we-dichloromethane: ethanol, ayinyibiliki emanzini, i-ethanol kunye ne-ether.
Ukusetyenziswa: Njengezinto zokugquma zethebhulethi, izinto zokugquma ezikhutshwayo ezihlala ixesha elide kunye nezinto zokugquma zefilimu.
10. I-Agar:
Ulwakhiwo: I-Agar ngumxube wee-polysaccharides ezimbini ubuncinane, malunga ne-60-80% ye-agarose engathathi hlangothi kunye ne-20-40% ye-agarose. I-Agarose yenziwe ngeeyunithi eziphindaphindayo ze-agarobiose apho i-D-galactopyranosose kunye ne-L-galactopyranosose zidibene ngokutshintshana kwi-1-3 kunye ne-1-4.
Iimpawu: I-Agar ikhanya, iyisilinda yesikwere esityheli esikhanyayo, inemigca emincinci okanye ineziqwenga ezinamagqabi okanye into efana nomgubo. Ayinyibiliki emanzini abandayo, iyanyibilika emanzini abilayo. Idumba izihlandlo ezingama-20 emanzini abandayo.
Ukusetyenziswa: Njenge-arhente yokubopha, isiseko seoyile, isiseko sesuppository, i-emulsifier, i-stabilizer, i-agent yokumisa, ikwayi-poultice, i-capsule, isiraphu, ijeli kunye ne-emulsion.
Ixesha leposi: Epreli-26-2024