Ngatitaurei nezve hydroxypropyl methyl celluloseHPMCuye kuti tingayera sei viscosity yayo. Viscosity pano inoreva viscosity inoonekwa, iyo inokosha inoreva hydroxypropyl methyl cellulose.
Standard. Nzira dzekuyera dzakajairika ndedzekuyera kutenderera kwe viscosity, kuyerwa kwe capillary viscosity uye kuyerwa kwe fall viscosity. Nzira yekuona hydroxypropyl methyl cellulose yaive capillary adhesion.
Nzira yekuona dhigirii, uchishandisa Uchs viscometer. Kazhinji kuongorora mhinduro ndeye 2% mvura, fomura yacho ndeiyi: V=Kdt. V ndiyo viscosity mu mpa. s uye K ndiyo viscometer constant.
D ihuwandu hwezvinhu patembiricha isingachinji uye T inguva kubva kumusoro kusvika pasi kuburikidza ne viscometer mumasekonzi. Nzira iyi yekushanda inorema zvikuru, kana paine zvinhu zvisinganyunguduki.
Mashoko ari nyore kukonzera zvikanganiso, zvakaoma kuziva mhando yehydroxypropyl methyl cellulose. Iye zvino inoshandiswa zvakanyanya kuyera viscosity ye rotary viscometer, iyo inoshandiswa zvakanyanya muChina.
Fomura yeNDJ-1 viscometer ndeyekuti η=Kα. η ndiyo viscosity, zvakare mu mpa. s, K ndiyo coefficient yeviscometer, uye α ndiyo kuverenga kwepointer yeviscometer.
Nzira yekuedza viscosity yeHydroxypropyl methyl cellulose 2%:
1, nzira iyi yakakodzera pakuona dynamic viscosity yemvura dzisiri dzeNewtonian (polymer solution, suspension, emulsion dispersion liquid kana surfactant solution, nezvimwewo).
2. Zvishandiso nemidziyo
2.1 Rotary viscometer (NdJ-1 naNDJ-4 zvinodiwa neChinese Pharmacopoeia)
2.2 Kupisa nguva dzose mvura yekugezera yakanyatsorongeka tembiricha nguva dzose 0.10C
2.3 Dhigirii rekuongorora tembiricha i0.20C, iyo inoongororwa nguva nenguva.
2.4 Mita yefrequency Viscometers dzinoshandisa zviyero zvekusimbisa frequency (senge NDJ-1 na NDJ-4) dzinofanira kuchengetwa. Kururama kwe1%. A
8. Og yemuenzaniso yakayerwa nemazvo ndokuiswa mugaba rakaoma, rakareba re400mL. Wedzera inenge 100mL yemvura inopisa ine madhigirii 80-90 wokurunga kwemaminitsi gumi kuti iparadzaniswe.
Paradzira zvakaenzana, kurunga woisa mvura inotonhora kusvika ku400mL yese. Panguva iyi, kurunga nguva dzose kwemaminitsi makumi matatu kuti ugadzire 2% (W/W), woiisa mufiriji kuti itonhore kusvika yaita chando chakatetepa pamusoro.
Bvisa woisa mutangi rekupisa kwepakati kuti tembiricha yepakati irambe iri pa20 ℃ 0.1 ℃.
3.1 Kuiswa nekushanda kwemudziyo kunofanira kuitwa zvichienderana nemirairo yekushandisa yemudziyo, uye rotor yakakodzera nerotor inofanira kusarudzwa zvichienderana nehuwandu hwe viscosity yechigadzirwa chakaedzwa uye zvinopihwa ne pharmacopoeia pasi pechinyorwa chechigadzirwa.
Kumhanya kwekutenderera.
3.2 Gadzirisa tembiricha yemvura inodziya zvichienderana nechinhu chimwe nechimwe chinodhaka.
3.3 Chigadzirwa chekuyedza chakaiswa mumudziyo wakatarwa nemudziyo, uye Angle (a) yekutsauka yakayerwa zvichienderana nemutemo mushure memaminitsi makumi matatu ekupisa kwakasimba. Dzima mota woitangazve kuti ionekwe zvakare.
Musiyano uripo pakati peavhareji haufanirwe kudarika 3%, zvikasadaro chiyero chechitatu chinofanira kuitwa.
3.4 Verenga avhareji yehuwandu hwemiedzo miviri zvichienderana nefomula kuti uwane simba rinoshanduka rechigadzirwa chakaedzwa.
4. Nyora woverenga
4.1 Nyora modhi ye rotary viscometer, nhamba ye rotor uye kumhanya kwakashandiswa, viscometer constant (K 'value), tembiricha yakayerwa, uye chiyero chega chega. Kukosha.
Fomura yekuverenga ye4.2
Viscosity inochinja-chinja (MPa”s)=Ka apo K ndiyo viscometer constant inoyerwa nemvura yakajairwa ine viscosity inozivikanwa uye A ndiyo deflection Angle
Nguva yekutumira: Kubvumbi-25-2024