Bari mu yi magana game da hydroxypropyl methyl celluloseHPMCda kuma yadda za a auna dankonsa. Dankonsa a nan yana nufin dankonsa da ake gani, wanda muhimmin abu ne da ake nufi da hydroxypropyl methyl cellulose.
Na yau da kullun. Hanyoyin aunawa na yau da kullun sune auna danko na juyawa, auna danko na capillary da kuma auna danko na kaka. Hanyar tantance hydroxypropyl methyl cellulose ita ce mannewa na capillary.
Hanyar tantance digiri, ta amfani da na'urar auna Uchs. Yawanci tantance maganin shine kashi 2% na ruwan da aka yi amfani da shi, dabarar ita ce: V=Kdt. V shine danko a cikin mpa. s kuma K shine madaidaicin viscometer.
D shine yawan da ake samu a yanayin zafi mai ɗorewa, kuma T shine lokacin daga sama zuwa ƙasa ta hanyar na'urar auna sigina a cikin daƙiƙa. Wannan hanyar aiki ta fi wahala, idan akwai abu mara narkewa.
Kalmomi suna da sauƙin haifar da kurakurai, yana da wuya a gano ingancin hydroxypropyl methyl cellulose. Yanzu ana amfani da shi sosai don auna danko na rotary viscometer, wanda ake amfani da shi gabaɗaya a China.
Tsarin viscometer NDJ-1 shine η=Kα. η shine danko, kuma a cikin mpa. s, K shine ma'aunin viscometer, kuma α shine karatun mai nuna viscometer.
Hanyar gwajin danko na Hydroxypropyl methyl cellulose 2%:
1, wannan hanyar ta dace da tantance danko mai ƙarfi na ruwan da ba na Newton ba (maganin polymer, dakatarwa, ruwa mai watsawa na emulsion ko maganin surfactant, da sauransu).
2. Kayan aiki da kayan aiki
2.1 Na'urar auna sigina ta Rotary (NdJ-1 da NDJ-4 ana buƙatar su ta hanyar Pharmacopoeia na ƙasar Sin)
2.2 Daidaiton zafin jiki na ruwa mai tsafta daidaitacce 0.10C
2.3 Matsayin auna zafin jiki shine 0.20C, wanda ake tabbatarwa akai-akai.
2.4 Za a yi amfani da na'urorin auna mitar mita masu amfani da ma'aunin daidaita mita (kamar NDJ-1 da NDJ-4). Daidaito na 1%. A
8. An auna samfurin 0g daidai kuma an saka shi a cikin busasshen beaker mai tsawon 400mL. Sai a zuba kimanin 100mL na ruwan zafi mai digiri 80-90 sannan a gauraya na tsawon minti 10 don a raba shi.
A watsa a ko'ina, a juya sannan a zuba ruwan sanyi a cikin 400mL gaba ɗaya. A halin yanzu, a ci gaba da juyawa na tsawon minti 30 don yin maganin 2% (W/W), sannan a saka shi a cikin firiji don yin wanka da kankara har sai ya yi ƙanƙara mai laushi a saman.
Cire kuma saka a cikin tankin zafin jiki mai ɗorewa don kiyaye zafin jiki na tsakiya zuwa 20 ℃ 0.1 ℃.
3.1 Za a gudanar da shigarwa da aiki da kayan aikin bisa ga umarnin aiki na kayan aikin, kuma za a zaɓi rotor da rotor da suka dace bisa ga kewayon ɗanko na samfurin da aka gwada da kuma tanadin pharmacopoeia a ƙarƙashin rubutun samfurin.
Saurin juyawa.
3.2 Daidaita zafin ruwan da ke daidai da zafin jiki bisa ga ƙa'idar da ke ƙarƙashin kowane abu na magani.
3.3 An sanya samfurin gwajin a cikin akwati da kayan aikin suka ƙayyade, kuma an auna kusurwar karkacewa (a) bisa ga doka bayan mintuna 30 na yanayin zafi mai ɗorewa. Kashe injin kuma sake kunna shi don tantancewa sau ɗaya.
Bambancin da ke tsakanin matsakaicin ƙima bai kamata ya wuce kashi 3% ba, in ba haka ba ya kamata a yi ma'auni na uku.
3.4 Lissafa matsakaicin ƙimar gwaje-gwajen guda biyu bisa ga dabarar don samun ƙarfin kuzari na samfurin da aka gwada.
4. Yi rikodi kuma yi lissafi
4.1 Yi rikodin samfurin viscometer mai juyawa, lambar rotor da saurin da aka yi amfani da shi, ma'aunin viscometer (ƙimar K), zafin da aka auna, da kowace ma'auni. Ƙimar.
Tsarin lissafi na 4.2
Danko mai ƙarfi (MPa”s) = Ka inda K shine madaidaicin viscometer wanda aka auna tare da ruwa mai kama da na yau da kullun na danko da aka sani kuma A shine kusurwar karkacewa
Lokacin Saƙo: Afrilu-25-2024