Kodi hypromellose acid imagonjetsedwa ndi chiyani?

Hypromellose, yomwe imadziwikanso kuti hydroxypropyl methylcellulose (HPMC), siili ndi asidi kwenikweni. Komabe, kukana kwa asidi kwa hypromellose kumatha kukulitsidwa kudzera mu njira zosiyanasiyana zopangira.

Hypromellose imasungunuka m'madzi koma siisungunuka kwambiri m'zinthu zachilengedwe zosungunulira ndi zakumwa zopanda polar. Chifukwa chake, m'malo okhala ndi acidity, monga m'mimba, hypromellose imatha kusungunuka kapena kutupa pang'ono, kutengera zinthu monga kuchuluka kwa asidi, pH, ndi nthawi yomwe yakhudzidwa.

Pofuna kulimbitsa kukana kwa asidi wa hypromellose m'mankhwala, njira zophikira ma enteric nthawi zambiri zimagwiritsidwa ntchito. Ma enteric clothing amagwiritsidwa ntchito pamapiritsi kapena makapisozi kuti awateteze ku malo okhala ndi asidi m'mimba ndikuwathandiza kuti alowe m'malo okhala ndi asidi m'matumbo ang'onoang'ono asanatulutse zosakaniza zomwe zimagwira ntchito.

Zophimba za enteric nthawi zambiri zimapangidwa kuchokera ku ma polima omwe sagonjetsedwa ndi asidi wam'mimba, monga cellulose acetate phthalate (CAP), hydroxypropyl methylcellulose phthalate (HPMCP), kapena polyvinyl acetate phthalate (PVAP). Ma polima awa amapanga chotchinga choteteza kuzungulira piritsi kapena kapisozi, kuteteza kusungunuka msanga kapena kuwonongeka m'mimba.

Mwachidule, ngakhale kuti hypromellose yokha siilimbana ndi asidi, kukana kwake ndi asidi kumatha kukulitsidwa kudzera mu njira zopangira monga enteric covering. Njirazi zimagwiritsidwa ntchito kwambiri popanga mankhwala kuti zitsimikizire kuti zosakaniza zogwira ntchito zimaperekedwa bwino pamalo omwe akufuna kugwira ntchito m'thupi.