Acid hypromellose ọ na-eguzogide ọgwụ?

Hypromellose, nke a makwaara dị ka hydroxypropyl methylcellulose (HPMC), abụghị ihe na-eguzogide acid n'onwe ya. Agbanyeghị, enwere ike ime ka iguzogide acid nke hypromellose dịkwuo mma site na usoro nhazi dị iche iche.

A na-agbaze Hypromellose n'ime mmiri mana ọ naghị agbaze nke ọma n'ime ihe ndị na-agbaze ihe na ihe ndị na-abụghị polar. Ya mere, n'ebe acidic dị, dịka afọ, hypromellose nwere ike ịgbaze ma ọ bụ zaa ruo n'ókè ụfọdụ, dabere na ihe ndị dị ka mkpokọta acid, pH, na oge ọ na-ekpughe.

Iji melite iguzogide acid nke hypromellose n'ime ọgwụ, a na-ejikarị usoro mkpuchi enteric eme ihe. A na-etinye mkpuchi enteric na mbadamba ma ọ bụ kapsụl iji chebe ha pụọ ​​​​na gburugburu acidic nke afọ ma kwe ka ha banye na gburugburu ebe dị jụụ nke obere eriri afọ tupu ha ewepụta ihe ndị na-arụ ọrụ.

A na-ejikarị ihe mkpuchi enteric eme ihe site na polima ndị na-eguzogide acid gastric, dịka cellulose acetate phthalate (CAP), hydroxypropyl methylcellulose phthalate (HPMCP), ma ọ bụ polyvinyl acetate phthalate (PVAP). Polima ndị a na-emepụta ihe mgbochi nchebe gburugburu mbadamba ma ọ bụ capsule, na-egbochi mgbasa ma ọ bụ mmebi n'afọ.

Na nchịkọta, ọ bụ ezie na hypromellose n'onwe ya anaghị eguzogide acid, enwere ike ime ka iguzogide acid ya dịkwuo mma site na usoro nhazi dịka mkpuchi enteric. A na-ejikarị usoro ndị a eme ihe n'ọgwụ iji hụ na e nyere ihe ndị na-arụ ọrụ nke ọma n'ebe a chọrọ ka ọ rụọ ọrụ n'ahụ.