Ese aside ya hypromellose irarwanya?

Hypromellose, izwi kandi nka hydroxypropyl methylcellulose (HPMC), ntabwo irwanya aside mu buryo busanzwe. Ariko, kurwanya aside ya hypromellose bishobora kongerwa binyuze mu buryo butandukanye bwo kuyitera.

Hypromellose ishongeshwa mu mazi ariko ntishongeshwa cyane mu bintu bishongeshwa mu bimera no mu bintu bito bito. Kubwibyo, mu bidukikije birimo aside, nko mu gifu, hypromellose ishobora gushonga cyangwa kubyimba ku rugero runaka, bitewe n'ibintu nk'ubwinshi bwa aside, pH, n'igihe yakoreshejwe.

Kugira ngo hongerwe ubushobozi bwo kurwanya aside ya hypromellose mu miti, hakunze gukoreshwa uburyo bwo gusiga aside. Udupira two gusiga aside dushyirwa ku binini cyangwa mu turemangingo kugira ngo birinde aside yo mu gifu no gutuma ijya mu mara mato mbere yo kurekura ibintu bikora.

Ubusanzwe, ibinyabutabire bya enteric bikorerwa muri polymer zirwanya aside yo mu gifu, nka cellulose acetate phthalate (CAP), hydroxypropyl methylcellulose phthalate (HPMCP), cyangwa polyvinyl acetate phthalate (PVAP). Izi polymer zikora uruzitiro rurinda ibinini cyangwa capsule, bikarinda gushonga cyangwa kwangirika vuba mu gifu.

Muri make, nubwo hypromellose ubwayo idahangana na aside, ubudahangarwa bwayo bwa aside bushobora kongerwa binyuze mu buryo bwo gukora nk'ubushyuhe bwa enteric. Ubu buryo bukunze gukoreshwa mu buryo bw'imiti kugira ngo ibintu bikora bigere neza aho byagenewe gukora mu mubiri.