Ua kūpaʻa anei ka waikawa hypromellose?

ʻO Hypromellose, i ʻike ʻia hoʻi ʻo hydroxypropyl methylcellulose (HPMC), ʻaʻole ia he kūpaʻa kūlohelohe i ka waikawa. Eia nō naʻe, hiki ke hoʻonui ʻia ke kūpaʻa waikawa o ka hypromellose ma o nā ʻano hana hoʻohui like ʻole.

Hiki ke hoʻoheheʻe ʻia ka Hypromellose i ka wai akā ʻaʻole hiki ke hoʻoheheʻe ʻia i nā mea hoʻoheheʻe organik a me nā wai non-polar. No laila, i nā wahi waikawa, e like me ka ʻōpū, hiki i ka hypromellose ke hoʻoheheʻe a pehu paha i kekahi ʻano, ma muli o nā mea e like me ka nui o ka waikawa, pH, a me ka lōʻihi o ka hōʻike ʻana.

No ka hoʻomaikaʻi ʻana i ke kūpaʻa ʻakika o ka hypromellose i nā ʻano lāʻau lapaʻau, hoʻohana pinepine ʻia nā ʻano hana uhi enteric. Hoʻopili ʻia nā uhi enteric i nā papa a i ʻole nā ​​capsules e pale iā lākou mai ke kaiapuni acidic o ka ʻōpū a ʻae iā lākou e hele i loko o ke kaiapuni kūʻokoʻa o ka ʻōpū liʻiliʻi ma mua o ka hoʻokuʻu ʻana i nā mea hana.

ʻO ka maʻamau, hana ʻia nā uhi ʻōpū mai nā polymers i kū i ka waikawa gastric, e like me ka cellulose acetate phthalate (CAP), hydroxypropyl methylcellulose phthalate (HPMCP), a i ʻole polyvinyl acetate phthalate (PVAP). Hoʻokumu kēia mau polymers i kahi pale pale a puni ka papa a i ʻole ka capsule, e pale ana i ka hoʻoheheʻe mua ʻana a i ʻole ka hōʻino ʻana i loko o ka ʻōpū.

I ka hōʻuluʻulu manaʻo, ʻoiai ʻaʻole kūpaʻa ka hypromellose i ka waikawa, hiki ke hoʻonui ʻia kona kūpaʻa waikawa ma o nā ʻano hana hoʻohui e like me ka uhi ʻana o ka enteric. Hoʻohana pinepine ʻia kēia mau ʻano hana i nā ʻano hana lāʻau lapaʻau e hōʻoia i ka lawe pono ʻana o nā mea hana i kahi i manaʻo ʻia o ka hana i loko o ke kino.