I-Hydroxypropyl methylcellulose (HPMC)yi-ether exutyiweyo ye-cellulose engeyiyo ionic, enyibilikayo emanzini. Imbonakalo yayo imhlophe ukuya kotyheli kancinci njengomgubo okanye izinto ezinamaqhekeza, ayinancasa, ayinavumba, ayinatyhefu, izinzile kwiikhemikhali, kwaye iyanyibilika emanzini ukuze yenze isisombululo esigudileyo, esicacileyo nesixineneyo. Enye yezona mpawu zibalulekileyo ze-hydroxypropyl methylcellulose xa isetyenziswa kukuba yonyusa i-viscosity yolwelo. Isiphumo sokutyeba sixhomekeke kwinqanaba le-polymerization (DP) yemveliso, ukuxinana kwe-cellulose ether kwisisombululo samanzi, izinga lokucheba, kunye nobushushu besisombululo. Nezinye izinto.
01
Uhlobo lolwelo lwesisombululo samanzi se-HPMC
Ngokubanzi, uxinzelelo lolwelo kwi-shear flow lunokubonakaliswa njengomsebenzi wesantya sokucheba kuphela i-ƒ(γ), logama nje lungaxhomekekanga kwixesha. Ngokuxhomekeke kwimo ye-ƒ(γ), ulwelo lunokwahlulwa lube ziintlobo ezahlukeneyo, ezizezi: ulwelo lweNewtonian, ulwelo oludityanisiweyo, ulwelo lwe-pseudoplastic kunye nolwelo lweplastiki lweBingham.
Ii-ether ze-Cellulose zahlulwe zibe ziindidi ezimbini: enye yi-non-ionic cellulose ether kwaye enye yi-ionic cellulose ether. Kwi-rheology yezi ntlobo zimbini zee-ether ze-cellulose. U-SC Naik nabanye benze uphando olupheleleyo nolucwangcisiweyo malunga nezisombululo ze-hydroxyethyl cellulose kunye ne-sodium carboxymethyl cellulose. Iziphumo zibonise ukuba zombini izisombululo ze-non-ionic cellulose ether kunye nezisombululo ze-ionic cellulose ether zaziyi-pseudoplastic. Ukuhamba, oko kukuthi ukuhamba okungeyo-Newtonian, kusondela kwii-Newtonian liquids kuphela kumanqanaba aphantsi kakhulu. I-pseudoplasticity yesisombululo se-hydroxypropyl methylcellulose idlala indima ebalulekileyo ekusetyenzisweni. Umzekelo, xa isetyenziswa kwiingubo, ngenxa yeempawu zokunciphisa ukucheba kwezisombululo zamanzi, i-viscosity yesisombululo iyancipha ngokunyuka kwesantya sokucheba, okunceda ukusasazeka ngokulinganayo kwee-pigment particles, kwaye kwandisa ukugeleza kwengubo. Isiphumo sikhulu kakhulu; ngelixa siphumle, i-viscosity yesisombululo inkulu kakhulu, ethintela ngokufanelekileyo ukufakwa kwee-pigment particles kwingubo.
02
Indlela yoVavanyo lwe-HPMC Viscosity
Isalathisi esibalulekileyo sokulinganisa isiphumo sokutyeba kwe-hydroxypropyl methylcellulose kukutyeba okubonakalayo kwesisombululo samanzi. Iindlela zokulinganisa ukutyeba okubonakalayo zihlala ziquka indlela ye-capillary viscosity, indlela ye-rotational viscosity kunye nendlela ye-falling ball viscosity.
apho: yi-viscosity ebonakalayo, i-mPa s; i-K yi-viscometer constant; i-d yi-density yesampulu yesisombululo kwi-20/20°C; i-t lixesha lokuba isisombululo sidlule kwinxalenye ephezulu ye-viscometer siye kuphawu olusezantsi, s; Ixesha apho ioyile esemgangathweni idlula kwi-viscometer liyalinganiswa.
Nangona kunjalo, indlela yokulinganisa nge-capillary viscometer inzima ngakumbi. Ukuqina kwabaninziii-ether ze-celluloseKunzima ukuhlalutya usebenzisa i-capillary viscometer kuba ezi zisombululo ziqulathe inani elincinci lezinto ezinganyibilikiyo ezifunyanwa kuphela xa i-capillary viscometer ivaliwe. Ke ngoko, uninzi lwabavelisi basebenzisa ii-rotational viscometers ukulawula umgangatho we-hydroxypropyl methylcellulose. Ii-Brookfield viscometers zisetyenziswa kakhulu kumazwe angaphandle, kwaye ii-NDJ viscometers zisetyenziswa eTshayina.
03
Izinto ezichaphazela i-HPMC viscosity
3.1 Ubudlelwane nobungakanani bokuqokelelwa kwezinto
Xa ezinye iiparameter zingatshintshi, i-viscosity yesisombululo se-hydroxypropyl methylcellulose ihambelana neqondo le-polymerization (DP) okanye ubunzima be-molecular okanye ubude be-molecular chain, kwaye iyanda ngokunyuka kweqondo le-polymerization. Esi siphumo sibonakala ngakumbi kwimeko yeqondo eliphantsi le-polymerization kunakwimeko yeqondo eliphezulu le-polymerization.
3.2 Ubudlelwane phakathi kokuxinana kunye noxinzelelo
I-viscosity ye-hydroxypropyl methylcellulose iyanda ngokunyuka koxinzelelo lwemveliso kwisisombululo samanzi. Nokuba utshintsho oluncinci loxinzelelo luya kubangela utshintsho olukhulu kwi-viscosity. Nge-viscosity eqhelekileyo ye-hydroxypropyl methylcellulose Isiphumo sotshintsho loxinzelelo lwesisombululo kwi-viscosity yesisombululo sibonakala ngakumbi nangakumbi.
3.3 Ubudlelwane phakathi kwe-viscosity kunye ne-shear rate
Isisombululo samanzi se-hydroxypropyl methylcellulose sineempawu zokucheba. I-hydroxypropyl methylcellulose ye-viscosity eyahlukileyo ye-nominal ilungiswa ibe yi-2% yesisombululo samanzi, kwaye i-viscosity yayo kwizinga ezahlukeneyo ze-shear ilinganiswa ngokulandelelana. Iziphumo zezi zilandelayo Njengoko kubonisiwe kumfanekiso. Kwizinga eliphantsi le-shear, i-viscosity yesisombululo se-hydroxypropyl methylcellulose ayizange itshintshe kakhulu. Ngokunyuka kwezinga le-shear, i-viscosity yesisombululo se-hydroxypropyl methylcellulose ene-viscosity ephezulu ye-nominal yehla ngokucacileyo, ngelixa isisombululo esine-viscosity ephantsi singazange sehle ngokucacileyo.
3.4 Ubudlelwane phakathi kwe-viscosity kunye nobushushu
Ubushushu buphantsi kakhulu xa kufikwa kubushushu. Njengoko ubushushu busanda, ubushushu buyancipha. Njengoko kubonisiwe kumfanekiso, bulungiswa bube yisisombululo samanzi esinoxinzelelo lwe-2%, kwaye utshintsho lobushushu buphantsi xa kufikwa kubushushu luyalinganiswa.
3.5 Ezinye izinto ezinefuthe
I-viscosity yesisombululo samanzi se-hydroxypropyl methylcellulose ikwachaphazeleka zizinto ezongeziweyo kwisisombululo, ixabiso le-pH yesisombululo, kunye nokuwohloka kwe-microbial. Ngokwesiqhelo, ukuze kufumaneke ukusebenza ngcono kwe-viscosity okanye kuncitshiswe iindleko zokusetyenziswa, kuyimfuneko ukongeza ii-rheology modifiers, ezifana nodongwe, udongwe oluguquliweyo, umgubo we-polymer, i-starch ether kunye ne-aliphatic copolymer, kwisisombululo samanzi se-hydroxypropyl methylcellulose. , kwaye ii-electrolytes ezifana ne-chloride, i-bromide, i-phosphate, i-nitrate, njl. nazo zingongezwa kwisisombululo samanzi. Ezi zongezo aziyi kuchaphazela kuphela iipropati ze-viscosity zesisombululo samanzi, kodwa zikwachaphazela nezinye iipropati zokusetyenziswa kwe-hydroxypropyl methylcellulose ezifana nokugcinwa kwamanzi. , ukumelana nokuhla, njl.
I-viscosity yesisombululo samanzi se-hydroxypropyl methylcellulose ayichaphazeleki yi-asidi kunye ne-alkali, kwaye ngokubanzi izinzile kuluhlu lwe-3 ukuya kwi-11. Ingakwazi ukumelana nomlinganiselo othile wee-asidi ezibuthathaka, ezifana ne-formic acid, i-acetic acid, i-phosphoric acid, i-boric acid, i-citric acid, njl. Nangona kunjalo, i-acid exutyiweyo iya kunciphisa i-viscosity. Kodwa i-caustic soda, i-potassium hydroxide, amanzi elayimu, njl. ayinampembelelo ingako kuyo. Xa ithelekiswa nezinye ii-ethers ze-cellulose,i-hydroxypropyl methylcelluloseIsisombululo samanzi sinozinzo oluhle lokulwa neentsholongwane, isizathu esiphambili kukuba i-hydroxypropyl methylcellulose inamaqela angenamanzi anomlinganiselo ophezulu wokutshintshwa kunye nokuthintela amaqela angenamanzi. Nangona kunjalo, ekubeni impendulo yokutshintshwa idla ngokungahambelani, iyunithi ye-anhydroglucose engatshintshwanga itshatyalaliswa lula ziintsholongwane, nto leyo ebangela ukuwohloka kweemolekyuli ze-cellulose ether kunye noqhekeko lweketanga. Ukusebenza kukuba i-viscosity ebonakalayo yesisombululo samanzi iyancipha. Ukuba kuyimfuneko ukugcina isisombululo samanzi se-hydroxypropyl methylcellulose ixesha elide, kucetyiswa ukuba wongeze inani elincinci le-arhente yokubola ukuze i-viscosity ingatshintshi kakhulu. Xa ukhetha ii-arhente ezilwa nefungus, izigcini okanye iifungicides, kufuneka uqaphele ukhuseleko, kwaye ukhethe iimveliso ezingenabungozi emzimbeni womntu, ezineempawu ezizinzileyo kwaye ezingenavumba, ezifana nee-fungicides ze-DOW Chem's AMICAL, izigcini ze-CANGUARD64, ii-agents zebhaktheriya ze-FUELSAVER kunye nezinye iimveliso. zinokudlala indima efanayo.
Ixesha leposi: Epreli-28-2024