ʻO ka Hydroxypropyl methylcellulose (HPMC)he ʻetera hui ʻole-ionic, wai-soluble cellulose. He keʻokeʻo ke ʻano o ka pauka melemele iki a i ʻole ka mea granular, ʻono ʻole, ʻala ʻole, ʻaʻohe ʻawaʻawa, paʻa kemika, a hoʻoheheʻe ʻia i loko o ka wai e hana i kahi hopena laumania, moakaka a viscous. ʻO kekahi o nā waiwai koʻikoʻi o ka hydroxypropyl methylcellulose i ka hoʻohana ʻana, ʻo ia ka hoʻonui ʻana i ka viscosity o ka wai. Aia ka hopena mānoanoa i ke kekelē o ka polymerization (DP) o ka huahana, ka nui o ka cellulose ether i loko o ka hopena wai, ka wikiwiki o ka shear, a me ka mahana o ka hopena. A me nā mea ʻē aʻe.
01
ʻAno wai o ka hopena wai HPMC
Ma keʻano laulā, hiki ke hōʻike ʻia ke kaumaha o kahi wai i ke kahe ʻokiʻoki ma ke ʻano he hana o ka wikiwiki ʻokiʻoki ƒ(γ) wale nō, inā ʻaʻole ia e hilinaʻi i ka manawa. Ma muli o ke ʻano o ƒ(γ), hiki ke hoʻokaʻawale ʻia nā wai i nā ʻano like ʻole, ʻo ia hoʻi: nā wai Newtonian, nā wai dilatant, nā wai pseudoplastic a me nā wai plastik Bingham.
Ua māhele ʻia nā ethers cellulose i ʻelua mau māhele: ʻo kekahi he non-ionic cellulose ether a ʻo kekahi he ionic cellulose ether. No ka rheology o kēia mau ʻano ʻelua o nā ethers cellulose. Ua hana ʻo SC Naik et al. i kahi noiʻi hoʻohālikelike piha a ʻōnaehana ma nā hopena hydroxyethyl cellulose a me sodium carboxymethyl cellulose. Ua hōʻike nā hopena he pseudoplastic nā hopena non-ionic cellulose ether a me nā hopena ionic cellulose ether. ʻO nā kahe, ʻo ia hoʻi nā kahe non-Newtonian, e hoʻokokoke aku i nā wai Newtonian ma nā ʻano haʻahaʻa loa. He kuleana koʻikoʻi ka pseudoplasticity o ka hopena hydroxypropyl methylcellulose i ka noi. No ka laʻana, i ka wā e hoʻopili ʻia ai i loko o nā uhi, ma muli o nā ʻano lahilahi shear o nā hopena wai, e emi ana ka viscosity o ka hopena me ka piʻi ʻana o ka shear rate, kahi e kūpono ai i ka hoʻolaha like ʻana o nā ʻāpana pigment, a hoʻonui pū i ka fluidity o ka uhi. Nui loa ka hopena; ʻoiai i ka hoʻomaha ʻana, nui ka viscosity o ka hopena, kahi e pale pono ai i ka waiho ʻana o nā ʻāpana pigment i loko o ka uhi.
02
Ke ʻano hoʻāʻo ʻana o ka viscosity HPMC
ʻO kahi hōʻailona koʻikoʻi e ana i ka hopena mānoanoa o ka hydroxypropyl methylcellulose ʻo ia ka viscosity maopopo o ka hopena wai. ʻO nā ʻano ana o ka viscosity maopopo e komo pū me ke ʻano viscosity capillary, ke ʻano viscosity rotational a me ke ʻano viscosity pōpō hāʻule.
kahi: ʻo ia ka mānoanoa maopopo, mPa s; ʻo K ke kūpaʻa viscometer; ʻo d ka nui o ka hāpana hoʻonā ma 20/20°C; ʻo t ka manawa no ka hoʻonā e hele ai ma ka ʻaoʻao o luna o ka viscometer a i ka māka lalo, s; ana ʻia ka manawa e kahe ai ka ʻaila maʻamau ma o ka viscometer.
Eia nō naʻe, ʻoi aku ka paʻakikī o ke ʻano o ke ana ʻana me ka viscometer capillary. ʻO nā viscosities o nā mea he nuinā ethers cellulosehe paʻakikī ke kālailai me ka hoʻohana ʻana i ka viscometer capillary no ka mea aia kēia mau hopena i nā nui liʻiliʻi o nā mea hiki ʻole ke hoʻoheheʻe ʻia e ʻike wale ʻia ke ālai ʻia ka viscometer capillary. No laila, hoʻohana ka hapa nui o nā mea hana i nā viscometers rotational e kāohi i ka maikaʻi o ka hydroxypropyl methylcellulose. Hoʻohana pinepine ʻia nā viscometers Brookfield ma nā ʻāina ʻē, a hoʻohana ʻia nā viscometers NDJ ma Kina.
03
Nā mea e hoʻohuli ai i ka viscosity HPMC
3.1 Pilina me ke kekelē o ka hōʻuluʻulu ʻana
Ke noho mau nā palena ʻē aʻe i hoʻololi ʻole ʻia, ua like ka viscosity o ka hopena hydroxypropyl methylcellulose me ke kekelē o ka polymerization (DP) a i ʻole ke kaumaha molekala a i ʻole ka lōʻihi o ke kaulahao molekala, a piʻi me ka piʻi ʻana o ke kekelē o ka polymerization. ʻOi aku ka ʻike ʻia o kēia hopena ma ke ʻano o ke kekelē haʻahaʻa o ka polymerization ma mua o ke kekelē kiʻekiʻe o ka polymerization.
3.2 Pilina ma waena o ka mānoanoa a me ka noʻonoʻo ʻana
Hoʻonui ʻia ka mānoanoa o ka hydroxypropyl methylcellulose me ka hoʻonui ʻia ʻana o ka nui o ka huahana i loko o ka wai. ʻOiai kahi loli liʻiliʻi o ka nui e hana ai i kahi loli nui i ka mānoanoa. Me ka mānoanoa maʻamau o ka hydroxypropyl methylcellulose, ʻoi aku ka maopopo o ka hopena o ka loli o ka nui o ka hopena ma ka mānoanoa o ka hopena.
3.3 Pilina ma waena o ka mānoanoa a me ka wikiwiki o ka ʻoki ʻana
Loaʻa i ka wai hoʻoheheʻe ʻāpana ka waiwai o ka hydroxypropyl methylcellulose. Hoʻomākaukau ʻia ka hydroxypropyl methylcellulose o ka viscosity nominal like ʻole i loko o ka wai hoʻoheheʻe ʻāpana 2%, a ua ana ʻia kona viscosity ma nā ʻano shear like ʻole. Eia nā hopena e like me ka mea i hōʻike ʻia ma ke kiʻi. Ma ka shear rate haʻahaʻa, ʻaʻole i loli nui ka viscosity o ka hydroxypropyl methylcellulose solution. Me ka piʻi ʻana o ka shear rate, ua emi iki ka viscosity o ka hydroxypropyl methylcellulose solution me ka viscosity nominal kiʻekiʻe, ʻoiai ʻaʻole i emi iki ka viscosity o ka hydroxypropyl methylcellulose solution.
3.4 Pilina ma waena o ka mānoanoa a me ka mahana
Hoʻopilikia nui ʻia ka mānoanoa o ka hopena hydroxypropyl methylcellulose e ka mahana. Ke piʻi aʻe ka mahana, emi iho ka mānoanoa o ka hopena. E like me ka mea i hōʻike ʻia ma ke kiʻi, ua hoʻomākaukau ʻia i loko o kahi hopena wai me ka nui o 2%, a ua ana ʻia ka loli o ka mānoanoa me ka piʻi ʻana o ka mahana.
3.5 Nā kumu hoʻohuli ʻē aʻe
Hoʻopilikia pū ʻia ka viscosity o ka hopena wai o ka hydroxypropyl methylcellulose e nā mea hoʻohui i loko o ka hopena, ka waiwai pH o ka hopena, a me ka hoʻohaʻahaʻa microbial. ʻO ka maʻamau, i mea e loaʻa ai ka hana viscosity maikaʻi aʻe a i ʻole e hōʻemi i ke kumukūʻai o ka hoʻohana ʻana, pono e hoʻohui i nā mea hoʻololi rheology, e like me ka lepo, ka lepo i hoʻololi ʻia, ka pauka polymer, ka starch ether a me ka aliphatic copolymer, i ka hopena wai o ka hydroxypropyl methylcellulose. , a me nā electrolytes e like me ka chloride, bromide, phosphate, nitrate, a pēlā aku hiki ke hoʻohui ʻia i ka hopena wai. ʻAʻole wale kēia mau mea hoʻohui e hoʻopilikia i nā waiwai viscosity o ka hopena wai, akā e hoʻopilikia pū i nā waiwai noi ʻē aʻe o ka hydroxypropyl methylcellulose e like me ka paʻa ʻana o ka wai. , ke kū'ē ʻana i ke kaumaha, a pēlā aku.
ʻAneʻane ʻaʻole i hoʻopilikia ʻia ka mānoanoa o ka hopena wai o ka hydroxypropyl methylcellulose e ka waikawa a me ka alkali, a paʻa mau ia ma ka pae o 3 a 11. Hiki iā ia ke kū i kahi nui o nā waikawa nāwaliwali, e like me ka waikawa formic, ka waikawa acetic, ka waikawa phosphoric, ka waikawa boric, ka waikawa citric, a pēlā aku. Eia nō naʻe, e hōʻemi ka waikawa i hoʻopaʻa ʻia i ka mānoanoa. Akā, ʻaʻole nui ka hopena o ka soda caustic, potassium hydroxide, ka wai lime, a pēlā aku. Ke hoʻohālikelike ʻia me nā ethers cellulose ʻē aʻe,hydroxypropyl methylcelluloseHe kūpaʻa antimicrobial maikaʻi ka hopena wai, ʻo ke kumu nui ʻo ia ka hydroxypropyl methylcellulose i nā hui hydrophobic me ke kiʻekiʻe o ka pani ʻana a me ke kāohi steric o nā hui. Eia naʻe, ʻoiai ʻaʻole like ka hopena pani, ʻo ka ʻāpana anhydroglucose i hoʻololi ʻole ʻia e nā microorganisms ka mea maʻalahi loa e hoʻopau ʻia, e hopena ana i ka hōʻino ʻana o nā molekala cellulose ether a me ka ʻoki ʻana i ke kaulahao. ʻO ka hana, ʻo ia ka emi ʻana o ka viscosity maopopo o ka hopena wai. Inā pono e mālama i ka hopena wai o ka hydroxypropyl methylcellulose no ka manawa lōʻihi, ua ʻōlelo ʻia e hoʻohui i kahi liʻiliʻi o ka mea antifungal i ʻole e loli nui ka viscosity. I ke koho ʻana i nā mea anti-fungal, nā mea mālama a i ʻole nā fungicides, pono ʻoe e makaʻala i ka palekana, a koho i nā huahana ʻaʻole ʻawaʻawa i ke kino o ke kanaka, he mau waiwai paʻa a ʻaʻohe ʻala, e like me nā fungicides AMICAL a DOW Chem, nā mea mālama CANGUARD64, nā mea bacteria FUELSAVER a me nā huahana ʻē aʻe. hiki ke pāʻani i kahi hana like.
Ka manawa hoʻouna: ʻApelila-28-2024