Hydroxypropyl methylcellulose (HPMC)wani nau'in ether ne mai gauraye wanda ba na ionic ba, wanda ke narkewa cikin ruwa. Bayyanar sa fari ne zuwa launin rawaya kaɗan ko abu mai kauri, ba shi da ɗanɗano, ba shi da ƙamshi, ba shi da guba, yana da karko a sinadarai, kuma yana narkewa a cikin ruwa don samar da mafita mai santsi, bayyananne da ɗanɗano. Ɗaya daga cikin mahimman halayen hydroxypropyl methylcellulose a aikace shine yana ƙara ɗanɗano na ruwan. Tasirin kauri ya dogara da matakin polymerization (DP) na samfurin, yawan cellulose ether a cikin ruwan, ƙimar yankewa, da zafin maganin. Da sauran abubuwa.
01
Nau'in ruwa na ruwan HPMC
Gabaɗaya, damuwa ta ruwa a cikin kwararar yankewa za a iya bayyana ta a matsayin aikin ƙimar yankewa ƒ(γ kawai), matuƙar ba ya dogara da lokaci. Dangane da siffar ƒ(γ), ana iya raba ruwa zuwa nau'ikan daban-daban, wato: ruwayen Newtonian, ruwayen dilatant, ruwayen pseudoplastic da ruwayen filastik na Bingham.
An raba ƙwayoyin cellulose zuwa rukuni biyu: ɗaya shine cellulose ether mara ionic, ɗayan kuma shine ionic cellulose ether. Don ilimin halittar waɗannan nau'ikan cellulose ethers guda biyu. SC Naik da abokan aikinsa sun gudanar da cikakken bincike mai zurfi kuma mai tsari kan mafita na hydroxyethyl cellulose da sodium carboxymethyl cellulose. Sakamakon ya nuna cewa mafita na ether cellulose marasa ionic da mafita na ionic cellulose ether pseudoplastic ne. Guduwar ruwa, watau kwararar da ba ta Newtonian ba, suna kusantar ruwa na Newtonian ne kawai a ƙananan yawan ruwa. Pseudoplasticity na mafita na hydroxypropyl methylcellulose yana taka muhimmiyar rawa a aikace. Misali, lokacin da aka shafa a cikin shafa, saboda halayen rage shear na mafita na ruwa, dankowar maganin yana raguwa tare da ƙaruwar shear rate, wanda ke taimakawa wajen wargaza barbashi iri ɗaya na pigment, kuma yana ƙara yawan ruwan shafa. Tasirin yana da girma sosai; yayin da yake hutawa, dankowar maganin yana da girma sosai, wanda ke hana shigar da barbashi masu launin shuɗi a cikin shafa yadda ya kamata.
02
Hanyar Gwajin Danko ta HPMC
Muhimmin alamar auna tasirin kauri na hydroxypropyl methylcellulose shine bayyanar danko na ruwan da ke cikinsa. Hanyoyin auna danko na bayyane yawanci sun haɗa da hanyar danko na capillary, hanyar danko na juyawa da kuma hanyar danko na faduwa.
inda: shine bayyanannen danko, mPa s; K shine daidaitaccen viscometer; d shine yawan samfurin maganin a 20/20°C; t shine lokacin da maganin zai ratsa ta saman viscometer zuwa alamar ƙasa, s; Lokacin da man da aka saba amfani da shi ke gudana ta cikin viscometer ana auna shi.
Duk da haka, hanyar aunawa da na'urar auna capillary viscometer ta fi wahala. Danko na mutane da yawaƙwayoyin celluloseYana da wahalar yin nazari ta amfani da na'urar auna sigina ta capillary domin waɗannan mafita suna ɗauke da adadin abubuwa marasa narkewa waɗanda ake gano su ne kawai lokacin da aka toshe na'urar auna sigina ta capillary. Saboda haka, yawancin masana'antun suna amfani da na'urorin auna sigina masu juyawa don sarrafa ingancin hydroxypropyl methylcellulose. Ana amfani da na'urorin auna sigina ta Brookfield a ƙasashen waje, kuma ana amfani da na'urorin auna sigina ta NDJ a China.
03
Abubuwan da ke tasiri ga danko na HPMC
3.1 Alaƙa da matakin tarawa
Idan wasu sigogi ba su canza ba, danko na maganin hydroxypropyl methylcellulose yana daidai da matakin polymerization (DP) ko nauyin kwayoyin halitta ko tsawon sarkar kwayoyin halitta, kuma yana ƙaruwa tare da ƙaruwar matakin polymerization. Wannan tasirin ya fi bayyana a yanayin ƙarancin polymerization fiye da yanayin babban matakin polymerization.
3.2 Alaƙa tsakanin danko da yawan amfani
Dankowar hydroxypropyl methylcellulose yana ƙaruwa tare da ƙaruwar yawan sinadarin a cikin ruwan. Ko da ƙaramin canjin yawan sinadarin zai haifar da babban canji a cikin dankowar. Tare da ɗankowar hydroxypropyl methylcellulose. Tasirin canjin yawan sinadarin a kan dankowar ruwan yana ƙara bayyana.
3.3 Alaƙa tsakanin ɗanko da ƙimar yankewa
Maganin ruwa na Hydroxypropyl methylcellulose yana da ikon rage girman yanke. Ana shirya Hydroxypropyl methylcellulose na danko daban-daban zuwa ruwan da kashi 2% na ruwa, kuma ana auna dankonsa a nau'ikan yanke daban-daban bi da bi. Sakamakon kamar haka ne Kamar yadda aka nuna a cikin hoton. A ƙarancin zafin yanke, danko na maganin hydroxypropyl methylcellulose bai canza sosai ba. Tare da ƙaruwar saurin yankewa, danko na maganin hydroxypropyl methylcellulose tare da danko mafi girma ya ragu a bayyane, yayin da maganin da ke da ƙarancin danko bai ragu a bayyane ba.
3.4 Alaƙa tsakanin ɗanko da zafin jiki
Zafin jiki yana shafar dankowar maganin hydroxypropyl methylcellulose sosai. Yayin da zafin jiki ke ƙaruwa, dankowar maganin yana raguwa. Kamar yadda aka nuna a cikin hoton, an shirya shi a cikin ruwan da aka yi amfani da shi wajen samar da ruwa mai yawan kashi 2%, kuma ana auna canjin dankowar tare da karuwar zafin jiki.
3.5 Sauran abubuwan da ke tasiri
Dankowar ruwan maganin hydroxypropyl methylcellulose shima yana shafar abubuwan da ke cikin ruwan maganin, ƙimar pH na ruwan maganin, da kuma lalacewar ƙwayoyin cuta. Yawanci, domin samun ingantaccen aikin danko ko rage farashin amfani, ya zama dole a ƙara masu gyaran rheology, kamar yumbu, yumbu da aka gyara, foda polymer, sitaci ether da aliphatic copolymer, zuwa ruwan maganin hydroxypropyl methylcellulose., kuma ana iya ƙara electrolytes kamar chloride, bromide, phosphate, nitrate, da sauransu zuwa ruwan maganin. Waɗannan ƙarin ba wai kawai za su shafi halayen danko na ruwan maganin ba, har ma za su shafi wasu halayen aikace-aikacen hydroxypropyl methylcellulose kamar riƙe ruwa, juriyar sag, da sauransu.
Dankowar ruwan maganin hydroxypropyl methylcellulose kusan ba ta shafi acid da alkali ba, kuma gabaɗaya yana da ƙarfi tsakanin 3 zuwa 11. Yana iya jure wa wani adadin acid mai rauni, kamar formic acid, acetic acid, phosphoric acid, boric acid, citric acid, da sauransu. Duk da haka, acid mai ƙarfi zai rage danko. Amma caustic soda, potassium hydroxide, ruwan lemun tsami, da sauransu ba su da tasiri sosai a kai. Idan aka kwatanta da sauran cellulose ethers,hydroxypropyl methylcelluloseMaganin ruwa yana da kyakkyawan kwanciyar hankali na ƙwayoyin cuta, babban dalili shine hydroxypropyl methylcellulose yana da ƙungiyoyin hydrophobic tare da babban matakin maye gurbin da hana steric na ƙungiyoyi. Duk da haka, tunda amsawar maye gurbin yawanci ba iri ɗaya bane, sashin anhydroglucose mara maye gurbin yana lalacewa cikin sauƙi ta hanyar ƙwayoyin cuta, wanda ke haifar da lalacewar ƙwayoyin cellulose ether da yanke sarkar. Aikin shine cewa bayyanar danko na maganin ruwa yana raguwa. Idan ya zama dole a adana maganin ruwa na hydroxypropyl methylcellulose na dogon lokaci, ana ba da shawarar a ƙara ɗan ƙaramin adadin maganin antifungal don kada danko ya canza sosai. Lokacin zabar magungunan hana fungal, magungunan kiyayewa ko magungunan kashe ƙwayoyin cuta, ya kamata ku kula da aminci, kuma ku zaɓi samfuran da ba su da guba ga jikin ɗan adam, suna da kaddarorin da suka dace kuma ba su da wari, kamar su magungunan kashe ƙwayoyin cuta na DOW Chem, magungunan kiyayewa na CANGUARD64, wakilan ƙwayoyin cuta na FUELSAVER da sauran kayayyaki. na iya taka rawa daidai.
Lokacin Saƙo: Afrilu-28-2024