Ese uzi imikorere ya hydroxypropyl methylcellulose?

Hydroxypropyl methylcelluloseni ubwoko bwa eteri ivanze ya cellulose itari ionic. Bitandukanye na eteri ivanze ya methyl carboxymethyl cellulose ya ionic, ntabwo ihura n'ibyuma bikomeye. Bitewe n'ibipimo bitandukanye by'ingano ya methoxyl n'ingano ya hydroxypropyl muri hydroxypropyl methylcellulose n'ubucucike butandukanye, hari ubwoko bwinshi bufite imiterere itandukanye, urugero, ingano nyinshi ya methoxyl n'ingano nke ya hydroxypropyl. Imikorere yayo iri hafi y'iya methyl cellulose, mu gihe ingano nke ya methoxyl n'ingano nyinshi ya hydroxypropyl iri hafi y'iya hydroxypropyl methyl cellulose. Ariko, muri buri bwoko, nubwo hari ingano ntoya ya hydroxypropyl cyangwa ingano nto ya methoxyl, hari itandukaniro rikomeye mu gushonga mu binyabutabire cyangwa ubushyuhe bwa flocculation mu bisubizo by'amazi.

(1) Imiterere y'ingufu za hydroxypropyl methylcellulose

① Gushonga kwa hydroxypropyl methylcellulose mu maziHydroxypropyl methylcelluloseMu by’ukuri ni ubwoko bwa methylcellulose yahinduwe na propylene oxide (methoxy-propylene), bityo ikaba igifite imiterere imwe na methyl cellulose ifite imiterere isa n’iy’amazi akonje yo gushonga no kudashonga amazi ashyushye. Ariko, bitewe n’itsinda rya hydroxypropyl ryahinduwe, ubushyuhe bwayo bwo gushonga mu mazi ashyushye buri hejuru cyane ugereranije n’ubwa methyl cellulose. Urugero, ubushyuhe bwa hydroxypropyl methylcellulose amazi afite 2% methoxy content substitution degree DS=0.73 na hydroxypropyl content MS=0.46 ni 500 mpa·s kuri 20°C, kandi ubushyuhe bwayo bwa gel bushobora kugera hafi kuri 100°C, mu gihe methyl cellulose ku bushyuhe bumwe ari hafi 55°C gusa. Ku bijyanye no gushonga kwayo mu mazi, nayo yararushijeho kuba nziza cyane. Urugero, hydroxypropyl methylcellulose yavunitse (ifite ishusho y'urusenda 0.2 ~ 0.5mm kuri 20°C ifite ubushyuhe bwa 4% bw'amazi ya 2pa•s irashobora kugurwa ku bushyuhe bw'icyumba, irashongeshwa byoroshye mu mazi idakonje.

② Gushonga kwa hydroxypropyl methylcellulose mu bintu bisukura ibinyabuzima, gushonga kwa hydroxypropyl methylcellulose mu bintu bisukura ibinyabuzima nabyo ni byiza kuruta ibya methylcellulose. Methylcellulose igomba kugira igipimo cya methoxyl substitution cya 2.1 Ibicuruzwa byavuzwe haruguru, ariko birimo hydroxypropyl MS = 1.5 ~ 1.8 na methoxy DS = 0.2 ~ 1.0, hydroxypropyl methylcellulose ifite viscosity nyinshi ifite igipimo cya substitution kiri hejuru ya 1.8 ishongeshwa mu bisubizo bya methanoli na ethanoli, kandi ifite thermos-plasticity n'amazi. Ishongeshwa kandi mu bisukura hydrocarboni bya chlorine nka methylene chloride na chloroform, hamwe n'ibintu bisukura ibinyabuzima nka acetone, isopropanol na diacetone alcohol. Gushonga kwayo mu bintu bisukura ibinyabuzima ni byiza kuruta gushonga kw'amazi.

(2) Ibintu Bigira Ingaruka ku Bushyuhe bwa Hydroxypropyl Methyl Cellulose Uburyo busanzwe bwo kumenya ubushyuhe bwa hydroxypropyl methyl cellulose ni bumwe n’ubw’izindi ether za cellulose. Bipimirwa kuri 20°C hamwe n’umuti w’amazi wa 2% nk’uko bisanzwe. Ubushyuhe bw’umuti umwe bwiyongera uko ubushyuhe bwiyongera. Ku bicuruzwa bifite uburemere butandukanye bwa molekile ku bushyuhe bumwe, umuti ufite uburemere bwinshi bwa molekile uba ufite ubushyuhe bwinshi. Isano yawo n’ubushyuhe isa n’iya methyl cellulose. Iyo ubushyuhe buzamutse, ubushyuhe butangira kugabanuka, ariko iyo bugeze ku bushyuhe runaka, ubushyuhe buhita bwiyongera maze hakavuka ubushyuhe. Ubushyuhe bwa gel bw’ibicuruzwa bifite ubushyuhe buke buri hejuru. Agace ka gel ntabwo gafitanye isano gusa n’ubushyuhe bwa ether, ahubwo kandi gafitanye isano n’ikigereranyo cy’imiterere ya methoxyl group n’itsinda rya hydroxypropyl muri ether n’ingano y’igipimo cyose cyo gusimbuza. Tugomba kumenya ko hydroxypropyl methylcellulose nayo ari pseudoplastic, kandi umuti wayo uhoraho mu bushyuhe bw'icyumba nta kwangirika kwa viscosity keretse niba hari amahirwe yo kwangirika kwa enzyme.

(3) Uburyo umunyu wihanganira hydroxypropyl methylcellulose Kubera ko hydroxypropyl methylcellulose ari ether itari ionic, ntabwo ishyirwa mu mazi, bitandukanye n'izindi ether za ionic cellulose, nka carboxymethyl Base cellulose, mu gisubizo kugira ngo ihuze na iyoni z'icyuma gikomeye n'ingufu. Umunyu rusange nka chloride, bromide, fosfeti, nitrate, n'ibindi ntabwo bizagwa iyo byongewe mu gisubizo cyayo cy'amazi. Ariko, kongeramo umunyu bigira ingaruka ku bushyuhe bwa flocculation bw'igisubizo cyayo cy'amazi. Iyo igipimo cy'umunyu cyiyongera, ubushyuhe bwa gel buragabanuka. Iyo igipimo cy'umunyu kiri munsi y'aho flocculation igeze, ubushyuhe bw'igisubizo bukunda kwiyongera. Kubwibyo, ingano runaka y'umunyu yongerwamo, mu ikoreshwa, ishobora kugera ku bukungu. Kubwibyo, mu ikoreshwa rimwe na rimwe, ni byiza gukoresha uruvange rwa ether ya cellulose n'umunyu kuruta igipimo kinini cya ether kugira ngo ugere ku bunini.

(4) Aside ya Hydroxypropyl methylcellulose n'ubudahangarwa bwa alkali. Hydroxypropyl methylcellulose muri rusange irahamye kuri aside na alkali, kandi ntabwo ihinduka mu rugero rwa pH 2 ~ 12. Ishobora kwihanganira aside yoroshye, Nka aside formic, aside acetic, aside citric, aside succinic, aside fosforic, aside boric, nibindi. Ariko aside yikubisemo igira ingaruka zo kugabanya ubukana. Alkali nka caustic soda, caustic potash n'amazi y'indimu nta ngaruka bigira kuri yo, ariko zishobora kongera ubukana bw'umuti, hanyuma zikawugabanya buhoro buhoro.

(5) Uburyo bwo kuvanga hydroxypropyl methylcellulose Umuti wa hydroxypropyl methylcellulose ushobora kuvangwa n'ibinyabutabire bya polymer bishongera mu mazi kugira ngo bibe igisubizo kimwe kandi kibonerana gifite ubukana bwinshi. Ibinyabutabire bya polymer birimo polyethylene glycol, polyvinyl acetate, polysilicone, polymethylvinyl siloxane, hydroxyethyl cellulose, na methyl cellulose. Ibinyabutabire bifite molekile nyinshi nka gum arabic, locustbean gum, karaya gum, nibindi nabyo bihuye neza n'umuti wabyo. Hydroxypropyl methylcellulose ishobora kandi kuvangwa na mannitol ester cyangwa sorbitol ester ya aside stearic cyangwa aside palmitic, kandi ishobora kandi kuvangwa na glycerin, sorbitol na mannitol, kandi ibi binyabutabire bishobora gukoreshwa nka hydroxypropyl methylcellulose Plasticizer kuri cellulose.

(6) Ishobora gushonga mu mazi idashongaeteri za seluloseya hydroxypropyl methylcellulose ishobora gukora cross-linking yo hejuru hamwe na aldehydes, ku buryo izi ethers zishongeshwa mu mazi zishyirwa mu gisubizo kandi ntizishonge mu mazi. Aldehydes ituma hydroxypropyl methylcellulose idashongeshwa irimo formaldehyde, glyoxal, succinic aldehyde, adipaldehyde, nibindi. Mu gihe ukoresha formaldehyde, ugomba kwitabwaho cyane ku gipimo cya pH cy'igisubizo, muri byo glyoxal ikora vuba, bityo glyoxal ikoreshwa cyane nk'ikintu gihuza mu nganda. Igipimo cy'ubu bwoko bw'ikintu gihuza mu gisubizo ni 0.2% ~ 10% by'uburemere bwa ether, byaba byiza 7% ~ 10%, urugero, 3.3% ~ 6% bya glyoxal ni byo bikwiriye cyane. Muri rusange, ubushyuhe bwo kuvurwa ni 0 ~ 30℃, kandi igihe ni iminota 1 ~ 120. Uburyo bwo guhuza bugomba gukorwa mu gihe hari aside. Muri rusange, pH y'umuti ihinduka kuri 2 ~ 6 binyuze mu kongeramo aside ikomeye inorganic cyangwa aside karbokisilike organic mu muti, byaba byiza hagati ya 4 ~ 6, hanyuma hakongerwamo aldehydes kugira ngo habeho reaction crosslinking. Aside ikoreshwa ifite aside hydrochloric, aside sulfuric, aside phosphoric, aside formic, aside asetic, aside hydroxy-acetic, aside succinic cyangwa aside citric nibindi, aho hamwe na aside formic cyangwa aside asetic ari byiza, kandi aside formic ni nziza cyane. Aside na aldehyde bishobora kandi kongerwamo icyarimwe kugira ngo umuti ugere kuri reaction crosslinking mu rugero rwa pH wifuza. Iyi reaction ikunze gukoreshwa mu gikorwa cya nyuma cyo gutunganya mu gutegura ether za cellulose. Iyo ether ya cellulose idashongeshejwe, biroroshye kuyikoresha.

Amazi afite ubushyuhe bwa 20~25°C yo koza no gusukura. Iyo icyo gicuruzwa kiri gukoreshwa, ibintu birimo alkali bishobora kongerwa mu gisubizo cy'icyo gicuruzwa kugira ngo pH y'icyo gisubizo ihinduke alkali, kandi icyo gisubizo kizashonga vuba. Ubu buryo bukoreshwa no mu gutunganya firime nyuma y'uko umuti wa eteri ya cellulose ukozwemo firime kugira ngo ube firime idashonga.

(7) Ubudahangarwa bwa enzyme ya hydroxypropyl methylcellulose mu buryo bw’imitekerereze ni ibintu bikomoka kuri cellulose, nka buri tsinda rya anhydroglucose, iyo hari itsinda rifatanye neza, ntabwo byoroshye kwanduzwa na mikorobe, ariko mu by’ukuri umusaruro urangiye Iyo agaciro k’inyongera karenze 1, kazangirika na enzymes, bivuze ko urwego rwo gusimbuza buri tsinda ku muyoboro wa cellulose rudahagije, kandi mikorobe zishobora kwangirika ku itsinda rya anhydroglucose ritasimbuwe kugira ngo rikore isukari, nk'intungamubiri kugira ngo mikorobe zishobore kwinjiza. Kubwibyo, niba urwego rwo gusimbuza cellulose ether rwiyongera, ubudahangarwa bwo kwangirika kwa enzyme ya cellulose ether nabwo buziyongera. Nk’uko raporo zibigaragaza, mu gihe cy’igenzura, ingaruka za hydrolysis z’imisemburo ikorwa, ubukana busigaye bwa hydroxypropyl methylcellulose (DS = 1.9) ni 13.2%, methylcellulose (DS = 1.83) ni 7.3%, methylcellulose (DS = 1.66) ni 3.8%, na hydroxyethyl cellulose ni 1.7%. Bigaragara ko hydroxypropyl methylcellulose ifite ubushobozi bukomeye bwo kurwanya enzymes. Kubwibyo, hydroxypropyl methylcellulose ifite ubushobozi bwo kurwanya enzymes. Kubwibyo, hydroxypropyl methylcellulose ifite ubudahangarwa bwiza bwa enzymes, hamwe n’ubushobozi bwayo bwiza bwo gukwirakwira, gukomera no gukora filime, ikoreshwa mu gupfuka amazi, nibindi, kandi muri rusange ntabwo ikeneye kongeramo ibintu bibungabunga. Ariko, kugira ngo umuti ubikwe igihe kirekire cyangwa bishobora kwanduzwa n’inyuma, ibintu bibungabunga bishobora kongerwaho nk'uburyo bwo kwirinda, kandi amahitamo ashobora kugenwa hakurikijwe ibisabwa bya nyuma by’umuti. Phenylmercuric acetate na manganese fluorosilicate ni ibintu bibungabunga neza, ariko byose bifite uburozi, bigomba kwitabwaho ku mikorere. Muri rusange, 1-5mg ya acetate ya phenylmercury ishobora kongerwamo umuti kuri litiro imwe y'igipimo.

(8) Imikorere yahydroxypropyl methylcelluloseFilimi Hydroxypropyl methylcellulose ifite ubushobozi bwiza bwo gukora filime. Umuti wayo w'amazi cyangwa umuti wa organic solvent utwikiriwe ku isahani y'ikirahure, kandi uba udafite ibara kandi ubonerana nyuma yo kuma. Kandi ufite filime ikomeye. Irwanya ubushuhe kandi ikomeza gukomera ku bushyuhe bwinshi. Iyo hongewemo pulasitiki ya hygroscopic, uburebure bwayo n'ubushobozi bwayo bworoshye bishobora kwiyongera. Mu bijyanye no kunoza ubworoherane, pulasitiki nka glycerin na sorbitol ni byo bikwiriye cyane. Muri rusange, ingano y'umuti ni 2% ~ 3%, kandi ingano ya pulasitiki ni 10% ~ 20% ya ether ya cellulose. Iyo pulasitiki irimo ubwinshi bukabije, amazi ya colloidal agabanuka iyo hari ubushuhe bwinshi. Ingufu zo gukurura za filime iyo hongeweho pulasitiki ni nini cyane kuruta iyo hatarimo pulasitiki, kandi ziyongera uko umubare wiyongereye. Ku bijyanye na hygroscopicity ya filime, nayo iriyongera uko ingano ya pulasitiki yiyongera.