HEC na HPMC

Haịdroxyethyl Cellulose (HEC)naHydroxypropyl Methylcellulose (HPMC)Ha abụọ bụ cellulose ethers na-anaghị agbaze na mmiri, nke sitere na cellulose eke. A na-ejikarị ha eme ihe n'ụlọ ọrụ mmepụta ihe, ọgwụ, nlekọta onwe onye, ​​na nri n'ihi na ha nwere ezigbo ihe ndị na-eme ka ha sie ike, na-emepụta ihe nkiri, na-eme ka ha sie ike, na-emekwa ka emulsion dị mma. Ọ bụ ezie na ha nwere ụfọdụ ihe yiri ya na mmalite na ọrụ ha, ọdịiche ha na nhazi kemịkalụ na-eme ka e nwee ihe ndị dị iche iche na ojiji ha.

1. Mmalite na Nhazi Kemịkalụ

Cellulose Ethers

A na-emepụta ma HEC ma HPMC site na ịgbanwe cellulose eke site na kemịkalụ, nke bụ polima nke mejupụtara β-D-glucose units jikọtara ya na β(1→4) glycosidic bonds. Cellulose n'onwe ya anaghị agbaze na mmiri, mana site na mgbanwe kemịkalụ, enwere ike ịgbanwe ya ka ọ bụrụ ihe ndị na-agbaze na mmiri.

Haịdroxyethyl Cellulose (HEC)

A na-emepụta HEC site na iji ethylene oxide meghachi omume na cellulose, na-ewebata otu hydroxyethyl (-CH2CH2OH) n'akụkụ yinye polymer. Mgbanwe a na-eme ka mmiri na-agbaze ma na-eme ka ikike nke polymer ahụ ịmepụta ngwọta doro anya ma kwụsie ike. Mgbanwe a na-emekarị na saịtị hydroxyl (-OH) nke nkeji anhydroglucose dị na yinye cellulose.

Hydroxypropyl Methylcellulose (HPMC)

A na-emepụta HPMC site na iji methyl chloride na propylene oxide na-emeghachi omume na cellulose, nke na-eme ka e jiri methoxy (-OCH3) na hydroxypropyl (-CH2CHOHCH3) dochie otu hydroxyl. Enwere ike ịgbanwe oke nke methoxy na ọdịnaya hydroxypropyl iji mee ka njirimara nke polymer ahụ dị iche.

2. Àgwà Anụ Ahụ

Mmiri na-agbaze

HEC: A na-agbaze n'ime mmiri ọkụ na mmiri oyi, na-emepụta mmiri doro anya ma na-agbaze agbaze. Ọ naghị agbaze n'ọtụtụ ihe ndị na-agbaze n'ime ihe ndị dị ndụ.

HPMC: A na-agbazekwa ya na mmiri oyi mana ọ na-emepụta jel mgbe a na-ekpo ọkụ. Ọ naghị agbaze na mmiri ọkụ mana ọ na-aza ma na-emepụta jel ndị a na-agbanwe agbanwe mgbe a na-ekpo ọkụ, nke bara uru na nnyefe ọgwụ a na-achịkwa achịkwa. Ụfọdụ ọkwa nwekwara ike ịgbaze na ihe mgbaze organic dị ka ethanol ma ọ bụ acetone.

Viscositi

A pụrụ imepụta ma HEC ma HPMC n'ọkwa dị iche iche nke viscosity. Ngwọta HEC na-enye nghọta dị elu ma anaghị emetụta okpomọkụ. viscosity HPMC na-adịkwu mma n'ofe oke pH (3-11) ma nwee ezigbo omume pseudoplastic (ịkpụcha akpụkpọ ahụ), nke bara uru na mkpuchi na ọgwụ.

Gelation okpomọkụ

HEC: Anaghị egosipụta njikọta okpomọkụ.

HPMC: Na-egosipụta njikọta okpomọkụ. Mgbe a kpochara ya ọkụ, ihe ngwọta polymer na-agafe mgbanwe nkebi, na-agbanwe ghọọ gel. A na-eji nke a eme ihe n'ụdị nri na ọgwụ.

3.Akwa Ọrụ

4. Ngwa

Haịdroxyethyl Cellulose (HEC)

A na-eji HEC eme ihe n'ọtụtụ ebe n'ọrụ ndị chọrọ njikwa viscosity na nkwụsi ike, ọkachasị na sistemụ mmiri.

Agba na Mkpuchi: A na-eji ya eme ihe dị ka ihe na-eme ka agba sie ike ma na-eme ka ọ sie ike iji gbochie agba ịda ma melite njirimara ojiji.

Nlekọta Onwe Onye: A na-ahụ ya na shampoos, ihe mkpuchi ihu, na ude maka ihe ndị na-eme ka ọ sie ike ma na-agbanwe ọdịdị ahụ.

Ọgwụ: A na-eji ya eme ihe dị ka ihe na-ejikọ ihe na ihe na-eme ka ọ sie ike n'ime ọgwụ ndị e ji mee ihe n'elu ahụ.

Ọrụ owuwu: Na simenti na ngwa agha dị ka ihe na-ejide mmiri ma na-eme ka ọrụ dịkwuo mma.

Kemịkalụ Ebe Oilfield: A na-eji ya eme ihe maka njikwa viscosity na igbochi mfu mmiri.

Hydroxypropyl Methylcellulose (HPMC)

A maara HPMC maka ọtụtụ ihe dị iche iche ọ na-eme na sistemụ nnyefe ọgwụ na-amịpụta mmiri na nke a na-achịkwa, yana dịka ihe na-ejikọ ma ọ bụ ihe nkiri.

Ọgwụ: A na-ejikarị ya eme ihe na mbadamba ọnụ (dịka ihe na-ejikọ ihe, ihe mkpuchi, ma ọ bụ ihe eji eme ka a tọhapụ ya), ihe ngwọta anya, na gels dị n'elu ahụ.

Ụlọ Ọrụ Nri: A kwadoro ya dị ka ihe mgbakwunye nri (E464) ma jiri ya mee ihe dị ka ihe na-eme ka ihe sie ike, ihe na-eme ka ihe sie ike, na ihe na-eme ka ihe sie ike.

Ọrụ owuwu: A na-eji ya eme ihe n'ime ngwa agha akọrọ, ihe ndọda taịlị, na ihe e ji emechi ihe maka ime ka mmiri dịgide, ịrapara, na ịrụ ọrụ nke ọma.

Ihe ịchọ mma: A na-eji ude, gel, na mmiri anya eme ihe.

Agba: Yiri HEC, nke e ji mee ihe n'ụdị mmiri maka njikwa rheology

5. Isi ihe dị iche

6. Nchekwa na Ndakọrịta Bio

A na-ewere ma HEC ma HPMC dị ka ihe dị nchebe ma ghara imebi ahụ. A naghị etinye ha n'ime sistemu mgbe ejiri ha mee ihe n'elu ma ọ bụ n'ọnụ n'ọtụtụ ihe a na-ahụkarị. HPMC nwere ọnọdụ GRAS (Generally Recognized as Safe) ma a na-ejikarị ya eme ihe n'ọtụtụ ebe na ụlọ ọrụ ọgwụ na nri n'ihi na ọ na-adaba na biocompatibility na nnabata iwu.

HEC na HPMC ha dị iche iche, polima ndị na-agbaze mmiri nwere ihe pụrụ iche ahaziri maka mkpa ụlọ ọrụ mmepụta ihe na ọgwụ. Ọ bụ ezie na ha abụọ na-enye ọrụ dị mma nke na-eme ka ihe sie ike ma na-eme ka ọ sie ike, HPMC pụtara ìhè na ngwa ọgwụ na nri n'ihi njikọta okpomọkụ ya na biocompatibility. N'aka nke ọzọ, HEC na-adịkarị na ngwa ndị dabere na mmiri dịka agba na ihe ịchọ mma n'ihi na o doro anya na ịdị n'otu ya na sistemụ mmiri.