Hydroxypropyl methyl cellulose HPMC waa isku-darka cellulose aan ionic ahayn oo ku jira noocyo kala duwan iyo ionic methyl carboxymethyl cellulose isku dhafan, kuma falgasho biraha culus. Hal xag-jir oo oksijiin ah sababtoo ah maadada hydroxypropyl methyl cellulose iyo saamiga kala duwan ee maadada hydroxypropyl iyo viscosity, waxay noqdeen noocyo kala duwan oo ku saabsan waxqabadka, tusaale ahaan, maadada methoxyl sare iyo heerka hooseeya ee noocyada hydroxypropyl, waxqabadkeedu wuxuu u dhow yahay methyl cellulose iyo heerka methoxyl hooseeya iyo heerka sare ee noocyada hydroxypropyl, waxqabadkeeduna wuxuu u dhow yahay hydroxypropyl methyl cellulose ayaa la soo saaraa. Laakiin nooc kasta, inkastoo uu ka kooban yahay oo keliya xaddi yar oo hydroxypropyl ah ama xaddi yar oo methoxy ah, milmida dareeraha dabiiciga ah ama heerkulka flocculation ee xalka biyaha, waxaa jira farqi weyn.
1, milmida cellulose-ka hydroxypropyl methyl
Hydroxypropyl methyl cellulose ee ku milmida biyaha ee hydroxypropyl methyl cellulose dhab ahaantii waa nooc ka mid ah propylene oxide (ring methyl oxypropyl) oo methyl cellulose wax laga beddelay, sidaa darteed wali waxay la mid tahay methyl cellulose biyaha qabow ee milmi kara iyo biyaha kulul ee aan milmi karin. Si kastaba ha ahaatee, heerkulka gelation ee hydroxypropyl wax laga beddelay ayaa aad uga sarreeya kan methyl cellulose ee biyaha kulul. Tusaale ahaan, dheellitirka xalka biyaha ee hydroxypropyl methylcellulose oo leh 2% methoxy content DS=0.73 iyo hydroxypropyl content MS=0.46 waa 500 mpa at 20℃. Heerkulka jel ee badeecada S waa ku dhow yahay 100℃, halka tan methyl cellulose ee heerkulka isku midka ah uu yahay qiyaastii 55℃ oo keliya. Marka laga hadlayo milmida biyaha, sidoo kale si weyn ayay u soo hagaagtay, tusaale ahaan, ka dib markii la burburiyay hydroxypropyl methylcellulose (qaabka hadhuudhka 0.2 ~ 0.5mm at 20℃ 4% viscosity biyood ah oo ah 2pA? S alaabta si fudud ayaa loogu milmi karaa biyaha iyada oo aan lagu qaboojin heerkulka qolka.
(2) Hydroxypropyl methyl cellulose ee dareeraha organic-ga milmida hydroxypropyl methyl cellulose ee dareeraha organic-ga milmida, sidoo kale waa ka fiican yahay methyl cellulose, methyl cellulose waxay u baahan tahay heerka beddelka methoxy ee 2.1 ama ka badan badeecooyin, waxayna ka kooban tahay hydroxypropyl MS=1.5~1.8 iyo methoxy DS=0.2~1.0, Dheefshiid sare hydroxypropyl methyl cellulose oo leh heerka beddelka guud ee ka sarreeya 1.8 ayaa ku milma xalalka methanol iyo ethanol ee aan biyaha lahayn, waxayna leedahay milmida thermoplastic iyo biyaha. Waxa kale oo ku milma hydrocarbons-ka chlorine-ka leh sida dichloromethane iyo trichloromethane, iyo dareerayaasha organic-ga sida acetone, isopropyl alcohol, iyo diacetone alcohol. Milmida dareeraha organic-ga ayaa ka sarreeya milmida biyaha.
2, dheellitirka hydroxypropyl methyl cellulose ee arrimaha saameeya
Waxyaabo ku saabsan dheellitirka hydroxypropyl methylcellulose go'aaminta dheellitirka hydroxypropyl methylcellulose, iyo ether-ka kale ee cellulose waa isku mid, waxay ku jiraan 20℃ oo leh 2% xal biyood ah sida go'aaminta caadiga ah. Dheefshiidka isla badeecada, iyadoo la kordhinayo fiirsashada iyo kororka, isku-darka isku midka ah ee alaabada miisaanka molecular-ka kala duwan, miisaanka molecular-ka ee badeecaddu waa dheellitirka sare. Xiriirka ay la leedahay heerkulka wuxuu la mid yahay kan methyl cellulose. Marka heerkulku kor u kaco, dheellitirka si lama filaan ah ayuu u kordhaa oo jeleynta ayaa dhacda. Heerkulka jeleynta ee alaabada leh dheellitirka hooseeya ayaa ka sarreeya kan alaabada leh dheellitirka sare. Heerka dhibicda jelkeeda, marka lagu daro dheellitirka sare iyo kan hoose ee ether, laakiin sidoo kale saamiga halabuurka kooxda ether methoxy iyo hydroxypropyl iyo heerka guud ee beddelka ayaa la xiriira. Waa in la ogaadaa in hydroxypropyl methylcellulose sidoo kale uu yahay pseudoplastic; xalkeedu waa mid deggan marka lagu kaydiyo heerkulka qolka mana muujinayo wax burbur ah oo dheellitirka ah marka laga reebo suurtagalnimada jebinta enzymatic.
3, aashitada hydroxypropyl methyl cellulose iyo aashitada alkaline
Aashitada Hydroxypropyl methylcellulose alkali hydroxypropyl methylcellulose acid iyo alkali, guud ahaan waa mid deggan, heerka PH PH2 ~ 12 saameyn kuma yeelan, waxay u adkeysan kartaa xaddi gaar ah oo aashitada fudud ah, sida aashitada formic, aashitada acetic, citric acid, succinic acid, fosforic acid, boric acid, iwm. Laakiin aashitada xooggan waxay leedahay saameynta yareynta viscosity. Alkali sida soodhaha caustic, potassium caustic iyo biyaha lime ma laha saameyn, laakiin saameynta kordhinta viscosity-ga xalka ayaa si tartiib tartiib ah u yaraan doonta mustaqbalka.
4, hydroxypropyl methyl cellulose waa la isku dari karaa
Xalka Hydroxypropyl methyl cellulose waxaa lagu qasi karaa iskudhisyada polymer-ka ee biyaha ku milma, waxayna noqon karaan xal hufan oo isku mid ah oo leh dheellitirnaan sare. Iskudhisyadan molecular-ka sare leh waa polyethylene glycol, polyvinyl acetate, polysilicone, polymethyl vinyl siloxane iyo hydroxyethyl cellulose iyo methyl cellulose, iwm. Iskudhisyada polymer-ka dabiiciga ah sida gum Arabic, lows bean gum, thorn tree xanjo iyo wixii la mid ah ayaa sidoo kale leh isku-darka wanaagsan ee xalkeeda. Hydroxypropyl methyl cellulose sidoo kale waxaa lagu qasi karaa stearic acid ama palmitic acid mannitol ester ama sorbitol ester, laakiin sidoo kale glycerol, sorbitol iyo mannitol, iskudhisyadan waxaa loo isticmaali karaa sidii hydroxypropyl methyl cellulose plasticizer.
5, hydroxypropyl methyl cellulose oo aan milmi karin biyo milmi kara
Hydroxypropyl methyl cellulose cellulose oo aan milmi karin biyaha-milmi kara, waxay noqon kartaa isku xidhka dusha sare ee aldehydes, waxayna ka dhigtaa ether-kan biyaha ku milma ee ku soo qulqulaya xalka, inay noqdaan kuwo aan milmi karin biyaha. Oo samee aldehyde aan milmi karin hydroxypropyl methylcellulose, formaldehyde, glyoxal, succinaldehyde, dialdehyde, iwm., isticmaalka formaldehyde waa inuu fiiro gaar ah u yeeshaa qiimaha PH ee xalka, kaas oo falcelinta glyoxal ay si dhakhso leh u dhacdo, sidaa darteed wax soo saarka warshadaha waxaa badanaa loo isticmaalaa glyoxal sidii wakiil isku xidha. Qiyaasta noocan ah ee wakiilka isku xidha xalka waa 0.2% ~ 10% cufnaanta ether, ugu fiican waa 7% ~ 10%, sida isticmaalka glyoxal oo leh 3.3% ~ 6% ayaa ah kan ugu habboon. Heerkulka daaweynta guud waa 0 ~ 30℃, waqtigu waa 1 ~ 120 daqiiqo. Falcelinta isku xidhka ayaa loo baahan yahay in lagu sameeyo xaalado aashito ah. Guud ahaan, asiidh xoog leh oo aan organic ahayn ama asiidh carboxylic organic ah ayaa lagu daraa xalka si loogu hagaajiyo PH-ga xalka ilaa 2 ~ 6, gaar ahaan inta u dhaxaysa 4 ~ 6, ka dibna aldehydes ayaa lagu daraa falcelinta isku xidhka. Asiidhyada la isticmaalo waa hydrochloric acid, sulfuric acid, fosforic acid, formic acid, acetic acid, hydroxy acetic acid, succinic acid ama citric acid, kuwaas oo ay ku jiraan formic acid ama acetic acid ugu fiican, halka formic acid uu yahay kan ugu fiican. Asiidhyada iyo aldehydes ayaa sidoo kale lagu dari karaa isku mar si loogu oggolaado in xalka uu isku xidhmo heerka PH ee la rabo. Falcelintan waxaa badanaa loo isticmaalaa habka ugu dambeeya ee habka diyaarinta cellulose ether, si cellulose ether uusan u milmin, si fudud loo isticmaali karo biyo 20 ~ 25℃ ah si loo dhaqo oo loo nadiifiyo. Marka badeecada la isticmaalo, walxaha alkaline waxaa lagu dari karaa xalka badeecada si loogu hagaajiyo PH-ga xalka inuu noqdo alkaline, badeecadana si dhakhso ah ayaa loogu milmaa xalka. Habkan waxaa sidoo kale loo isticmaali karaa marka xalka cellulose ether loo isticmaalo sameynta filim ka dibna filimka lagu daweeyo inuu sameeyo filim aan milmi karin.
6, hydroxypropyl methyl cellulose anti-enzyme
Iska caabbinta enzyme-ka hydroxypropyl methyl cellulose ee derivatives cellulose aragti ahaan, sida kooxaha anhydroglucose kasta sida isku-darka adag ee kooxaha beddelaya, nabaad-guurka noolaha yar yar uma nugula caabuqa, laakiin dhab ahaantii badeecada la dhammeeyay si loogu beddelo qiimaha ka badan 1, sidoo kale iyada oo loo marayo burburinta enzyme-ka, tani waa sharraxaadda koox kasta oo ku jirta heerka beddelka silsiladda cellulose ma aha mid isku mid ah, Noolaha yaryar waxay baabi'in karaan kooxaha gulukooska ee aan la beddelin ee aan la beddelin si ay u sameeyaan sonkor, kuwaas oo ay nuugi karaan noolaha yaryar sida cuntada. Sidaa darteed, haddii heerka beddelka etherification ee cellulose uu kordho, iska caabbinta cellulose ether ee nabaad-guurka enzymatic ayaa la xoojin doonaa. Waxaa la soo sheegay in xaaladaha la xakameeyey, dheellitirka haraaga ah ee cellulose hydroxypropyl methyl (DS=1.9), methyl cellulose (DS=1.83), methyl cellulose (DS=1.66), iyo hydroxyethyl cellulose (1.7%) waxay ahaayeen 13.2%, 7.3%, 3.8%, iyo 1.7%, siday u kala horreeyaan. Hydroxypropyl methyl cellulose waxay leedahay awood xooggan oo ka-hortagga ensaymka. Sidaas darteed hydroxypropyl methylcellulose waa ka-hortagga ensaym-ka aadka u fiican, oo ay weheliso kala-fidintiisa wanaagsan, dhumucdiisa iyo sameynta filimka, oo lagu mariyo dahaarka emulsion-ka, iwm., guud ahaan uma baahna in lagu daro ilaaliyayaal. Si kastaba ha ahaatee, si looga hortago kaydinta muddada-dheer ee xalka ama wasakheynta suurtagalka ah ee ka timaadda adduunka dibadda, ilaaliyayaal ayaa lagu dari karaa, kuwaas oo xulashadooda lagu go'aamin karo iyadoo loo eegayo shuruudaha kama dambaysta ah ee xalka. Phenylmercuric acetate iyo manganese fluosilicate waa ilaaliyayaal wax ku ool ah, laakiin waa sun waana in si taxaddar leh loo shaqeeyaa. Guud ahaan, 1 ~ 5mg phenylmercuric acetate ayaa lagu dari karaa litir kasta oo xal ah.
7, waxqabadka xuubka cellulose hydroxypropyl methyl
Waxqabadka filimka Hydroxypropyl methyl cellulose ee hydroxypropyl methyl cellulose wuxuu leeyahay filim aad u fiican, xalka biyaha ama xalka dareeraha dabiiciga ah, oo lagu dahaadhay saxanka galaaska, ka dib marka la qalajiyo wuxuu noqdaa filim aan midab lahayn, hufan oo adag. Waxay leedahay iska caabin qoyaan wanaagsan waxayna sii ahaanaysaa mid adag heerkulka sare. Sida ku darista plasticizer-ka hygroscopic, waxay xoojin kartaa dheereynta iyo dabacsanaanta, si loo hagaajiyo dabacsanaanta, glycerol iyo sorbitol iyo plasticizer-ka kale ayaa ah kan ugu habboon. Xoogga guud ee xalka waa 2% ~ 3%, qiyaasta plasticizer-ka waa 10% ~ 20% cellulose ether. Haddii waxa ku jira plasticizer-ku uu yahay mid aan ku filnayn, dhacdada yaraanta ee fuuq-baxa colloid-ka ayaa dhici karta qoyaan badan. Xoogga jiidista ee plasticizer-ka filimka lagu daray aad ayuu uga weyn yahay kan aan lagu darin, wuxuuna kordhaa marka la kordhiyo xaddiga lagu daray, maadaama hygroscopicity-ga filimka sidoo kale la kordhiyo marka la kordhiyo xaddiga plasticizer-ka.
Waqtiga boostada: Sebteembar-08-2022