Hydroxypropyl methyl cellulose ndi carboxymethyl cellulose sodium zitha kusakanikirana

Kodi HPMC ndi CMC zingasakanizidwe?

Methyl celluloseNdi yoyera kapena yoyera ngati ufa wa ulusi kapena granular; Yopanda fungo, yopanda kukoma. Chogulitsachi m'madzi chimatupa kukhala yankho lomveka bwino kapena lopanda matope pang'ono; Chosasungunuka mu ethanol yeniyeni, chloroform kapena diethyl ether. Chimafalikira mwachangu ndikutupa m'madzi otentha pa 80-90 ℃, ndikusungunuka mwachangu mutazizira. Yankho lamadzi limakhala lokhazikika kutentha kwa chipinda, ndipo limatha kusungunuka kutentha kwambiri, ndipo gel imatha kusintha ndi yankho kutentha.

Ili ndi kunyowa kwabwino kwambiri, kufalikira, kumamatira, kukhuthala, kusakaniza, kusunga madzi ndi kupanga filimu, komanso kukana mafuta. Filimuyi ili ndi kulimba kwabwino, kusinthasintha komanso kuwonekera bwino. Chifukwa si ya ionic, imatha kugwirizana ndi ma emulsifier ena, koma ndi yosavuta kuichotsa mchere, ndipo yankho lake ndi lokhazikika pamlingo wa PH2 — 12. Sodium carboxymethyl cellulose Chogulitsachi ndi mchere wa sodium wa cellulose carboxymethyl ether, ndi cha anionic cellulose ether, ndi ufa woyera kapena wa mkaka kapena tinthu tating'onoting'ono, kachulukidwe ka 0.5-0.7 g/cubic centimeter, pafupifupi yopanda fungo, yopanda kukoma, yosakanikirana. Yosavuta kufalikira m'madzi mu yankho lowonekera la gelatinous, yosasungunuka mu ethanol ndi zosungunulira zina zachilengedwe.

Pamene pH ya yankho lamadzi ili 6.5 — 8.5, kukhuthala kwa slurry kumachepa kwambiri pamene pH ili >10 kapena <5, ndipo magwiridwe antchito ake ndi abwino kwambiri pamene pH ili 7. Kuti kutentha kukhale kolimba, kukhuthala kumakwera mofulumira pansi pa 20℃, kumasintha pang'onopang'ono pa 45℃, ndipo kukhuthala kwa colloid ndi kukhuthala ndi makhalidwe ake kumachepa kwambiri ikatenthedwa kwa nthawi yayitali kuposa 80℃. Yosungunuka mosavuta m'madzi, yankho lowonekera; Ndi lokhazikika kwambiri mu yankho la alkaline, ndipo ndi losavuta kulithira hydrolyze ngati asidi. Pamene pH ili 2-3, mvula imagwa, ndipo mvula imagwanso ngati mchere wachitsulo wambiri. Hydroxypropyl methyl cellulose, yomwe imadziwikanso kuti hydroxypropyl methyl cellulose, cellulose hydroxypropyl methyl ether, ndi kusankha cellulose ya thonje yoyera kwambiri ngati zinthu zopangira, pansi pa mikhalidwe ya alkaline pogwiritsa ntchito etherification yapadera ndi kukonzekera.

Amasungunuka m'madzi ndi polar C yambiri komanso kuchuluka koyenera kwa ethanol/madzi, propanol/madzi, dichloroethane, ndi zina zotero, osasungunuka mu diethyl ether, acetone, absolute ethanol, kutupa m'madzi ozizira kukhala yankho loyera kapena lopanda madzi pang'ono. Yankho lamadzi lili ndi ntchito pamwamba, mawonekedwe apamwamba komanso magwiridwe antchito okhazikika.HPMCIli ndi mphamvu ngati gel yotentha. Pambuyo potenthetsa, yankho lamadzi la mankhwalawa limapanga mpweya wa gel, kenako limasungunuka pambuyo pozizira. Kutentha kwa gel kosiyanasiyana kumasiyana.