HPMC (hydroxypropyl methylcellulose) chinhu chinonyungudika mumvura chinoshandiswa zvakanyanya mumabasa ekuvaka, mishonga, chikafu uye makemikari ezuva nezuva. Chine kukora kwakanaka, emulsification, film-forming, protective colloid nezvimwe zvinhu. Mu emulsion systems, HPMC inogona kudzora viscosity ye emulsion nenzira dzakasiyana-siyana.
1. Maumbirwo eHPMC eMolecular
Kuwanda kweHPMC kunonyanya kukanganiswa nehuremu hwayo hwemamorekuru uye mwero wekutsiva. Kukura kwehuremu hwemamorekuru, kukwira kwehuremu hwemushonga; uye mwero wekutsiva (ndiko kuti, mwero wekutsiva hydroxypropyl ne methoxy groups) unokanganisa kunyungudika uye hunhu hwehuremu hweHPMC. Zvikuru, mwero wekutsiva wakakwira, kunyungudika kwemvura kweHPMC kunowedzerawo, uye huremu hunokwira zvinoenderana. Vagadziri vanowanzopa zvigadzirwa zveHPMC huremu hwakasiyana hwemamorekuru uye mwero wekutsiva kuti zvizadzise zvinodiwa zvemashandisirwo akasiyana.
2. Shandisa kutarisisa
Kuwanda kweHPMC mumushonga wemvura ndeimwe yezvinhu zvikuru zvinokanganisa kukora kwemvura. Kazhinji, kuwanda kweHPMC, ndiko kuwanda kwemushonga. Zvisinei, kukora kwemhando dzakasiyana dzeHPMC pamushonga mumwe chete kunogona kusiyana zvakanyanya. Saka, mukushandiswa kwesimba, zvakakosha kusarudza kuwanda kwakakodzera kwemushonga weHPMC zvichienderana nezvinodiwa zvekukora. Semuenzaniso, mukushandiswa kwekuvaka, kuwanda kweHPMC kunowanzo dzorwa pakati pe0.1% ne1% kuti ipe kukora kwakakodzera uye kushanda zvakanaka kwekuvaka.
3. Nzira yekunyungudutsa
Maitiro ekunyungudika kweHPMC anewo simba guru pakunyungudika kwekupedzisira. HPMC iri nyore kupararira mumvura inotonhora, asi mwero wekunyungudika unononoka; inonyungudika nekukurumidza mumvura inopisa, asi iri nyore kuungana. Kuti usaungane, nzira yekuwedzera zvishoma nezvishoma inogona kushandiswa, ndiko kuti, kutanga wawedzera HPMC zvishoma nezvishoma mumvura inotonhora kuti ipararire, wozopisa wokurunga kusvika yanyungudika zvachose. Pamusoro pezvo, HPMC inogonawo kusanganiswa nedzimwe hupfu hwakaoma uye yozowedzerwa mumvura kuti inyungudike kuti ivandudze kushanda zvakanaka kwekunyungudika uye kugadzikana kwekunyungudika.
4. Tembiricha
Kupisa kune simba guru pakusimba kwemhinduro dzeHPMC. Kazhinji, simba rekusimba kwemhinduro dzeHPMC rinoderera sezvo tembiricha ichiwedzera. Izvi zvinodaro nekuti kukwira kwekupisa kunodzikisa simba rehydrogen bonding pakati pemamorekuru, zvichiita kuti HPMC molecular chain itsvedzere zviri nyore, nokudaro zvichideredza simba rekusimba kwemhinduro. Nokudaro, mukushandiswa kunoda simba rakawanda rekusimba, mhinduro dzeHPMC dzinowanzo shandiswa patembiricha yakaderera. Semuenzaniso, mukushandiswa kwemishonga, mhinduro dzeHPMC dzinowanzo shandiswa patembiricha yemukamuri kuti ive nechokwadi chekugadzikana uye kushanda kwemushonga.
5. kukosha kwepH
Kusimba kwemushonga weHPMC kunokanganiswawo nekusimba kwepH. HPMC ine kusimba kwakanyanya mumamiriro ezvinhu asina acid uye asina simba, nepo kusimba kuchaderera zvakanyanya mumamiriro ezvinhu ane acid kana alkaline. Izvi zvinodaro nekuti pH yakawandisa ichaparadza chimiro chemamorekuru eHPMC uye inoderedza simba rayo rekusimba. Saka, mukushandiswa kwaro, pH yemushonga inofanirwa kudzorwa uye kuchengetedzwa mukati mehuwandu hwakagadzikana hweHPMC (kazhinji pH 3-11) kuti ive nechokwadi chekuti inosimba. Semuenzaniso, mukushandiswa kwechikafu, HPMC inowanzo shandiswa muzvikafu zvine acid zvakaita seyogati nemuto, uye kusimba kwakakodzera kunogona kuwanikwa nekugadzirisa pH.
6. Zvimwe zvinowedzerwa
Muma emulsion systems, viscosity yeHPMC inogonawo kugadziriswa nekuwedzera mamwe ma thickeners kana solvents. Semuenzaniso, kuwedzera huwandu hwakakodzera hwe inorganic salts (senge sodium chloride) kunogona kuwedzera viscosity ye HPMC solution; nepo kuwedzera organic solvents senge ethanol kunogona kuderedza viscosity yayo. Pamusoro pezvo, kana ikashandiswa pamwe chete nedzimwe thickeners (senge xanthan gum, carbomer, nezvimwewo), viscosity uye kugadzikana kwe emulsion zvinogonawo kuvandudzwa zvakanyanya. Nokudaro, mukugadzira fomura chaiyo, zvinowedzera zvakakodzera zvinogona kusarudzwa sezvinodiwa kuti zviwedzere viscosity uye mashandiro e emulsion.
HPMC inogona kudzora emulsion viscosity nenzira chaiyo kuburikidza nechimiro chayo chemamorekuru, huwandu hwekushandiswa, nzira yekunyungudika, tembiricha, pH kukosha uye zvimwe zvinowedzera. Mukushandiswa kwaro, zvinhu izvi zvinofanirwa kutariswa zvakakwana kuti zvisarudzwe mhando yakakodzera yeHPMC nemamiriro ekushandisa kuti zviwane mhedzisiro yakanaka yekukora. Kuburikidza nekugadzira formula yesainzi uye kudzora maitiro, HPMC inogona kuita basa rakakosha muminda yekuvaka, mishonga, chikafu uye makemikari ezuva nezuva, ichipa mashandiro akanaka uye ruzivo rwemushandisi.
Nguva yekutumira: Chikunguru-17-2024