Hydroxypropyl methylcellulose (HPMC)he katote-kore, he wai-wairewa cellulose kua konatunatua ether. He ma te ahua ki te paura paku he kowhai, he mea kowhatu ranei, he kore reka, he kakara, he kore paitini, he matū matū, ka memeha ki te wai kia puta he otinga maeneene, marama, me te wairewa. Ko tetahi o nga mea tino nui o te hydroxypropyl methylcellulose i roto i te tono ko te whakanui ake i te kaha o te wai. Ko te kaha o te whakapakeke i runga i te tohu o te polymerization (DP) o te hua, te kukū o te cellulose ether i roto i te wairewa wai, te tere kutikuti, me te pāmahana otinga. Me etahi atu mea.
01
Momo wai o te wairewa wai HPMC
I te nuinga o te waa, ka taea te whakaatu i te ahotea o te wai i roto i te rere kutikuti hei mahi mo te tere kutikuti ƒ(γ) anake, mena karekau e whakawhirinaki ki te waa. I runga i te ahua o te ƒ(γ), ka taea te wehewehe i nga wai ki nga momo rereke, ara: nga wai Newtonian, nga wai rere, nga wai pseudoplastic me nga wai kirihou Bingham.
Kua wehea nga etera cellulose ki nga waahanga e rua: ko tetahi ko te katote cellulose ether me tetahi ko te katote cellulose ether. Mo te rheology o enei momo ethers cellulose e rua. SC Naik et al. i whakahaerehia he rangahau whakatairite matawhānui me te nahanaha mo nga wairewa hydroxyethyl cellulose me te konutai carboxymethyl cellulose. I kitea e nga hua ko nga otinga ether cellulose kore-katote me nga otinga ether cellulose eter he pseudoplastic. Ko nga rere, ara ko nga rerenga kore-Newtonian, ka whakatata ki nga wai Newtonian anake i te iti rawa o te kuhanga. Ko te pseudoplasticity o te otinga hydroxypropyl methylcellulose he mahi nui ki te tono. Hei tauira, i te wa e whakamahia ana i roto i nga paninga, na te ahua o te kutikuti angiangi o nga wairewa wai, ka heke te pokey o te otinga na te piki o te tere kutikuti, e pai ana ki te marara rite o nga matūriki poaka, me te whakanui ake i te rere o te paninga. He tino nui te paanga; i te wa e okioki ana, he ahua nui te pokey o te otinga, he pai te aukati i te tukunga o nga matūriki poaka i roto i te paninga.
02
Tikanga Whakamātautau HPMC Viscosity
Ko tetahi tohu nui hei ine i te whakamaarutanga o te hydroxypropyl methylcellulose ko te tino pokey o te wairewa wai. Ko nga tikanga inenga o te pokey kitea te tikanga ko te tikanga pokey capillary, te tikanga pokey takahuri me te tikanga pokey taka.
kei hea: ko te tino potata, mPa s; Ko te K te taumau o te viscometer; d ko te kiato o te tauira otinga i te 20/20°C; Ko t te wa mo te otinga kia haere ma te taha o runga o te inetere ki te tohu o raro, s; Ka inehia te wa e rere ai te hinu paerewa i roto i te viscometer.
Heoi, he raruraru ake te tikanga ine ma te viscometer capillary. Ko te viscosity o te tiniethers celluloseHe uaua ki te wetewete ma te whakamahi i te inenga kapi na te mea kei roto i enei rongoa he maha nga matū kore whakarewa ka kitea noa i te wa e parea ana te inenga kapi. Na reira, ko te nuinga o nga kaihanga e whakamahi ana i nga viscometers hurihuri hei whakahaere i te kounga o te hydroxypropyl methylcellulose. Kei te whakamahia nga viscometers Brookfield ki nga whenua ke, ka whakamahia nga viscometers NDJ i Haina.
03
Te awe i nga ahuatanga o te pokey HPMC
3.1 Te hononga ki te tohu o te whakahiato
Ina noho tonu etahi atu tawhā, ko te pokey o te wairewa hydroxypropyl methylcellulose he rite ki te tohu o te polymerization (DP) ranei te taumaha ngota, te roa o te mekameka ngota, ka piki ake i te piki o te tohu o te polymerization. Ko tenei paanga he nui ake te korero i roto i te waahanga iti o te polymerization i te ahua o te tohu teitei o te polymerization.
3.2 Te hononga i waenga i te pokey me te kukū
Ka piki te pokey o te hydroxypropyl methylcellulose ki te piki ake o te kukū o te hua i roto i te wairewa wai. Ahakoa te iti o te huringa kukū ka puta he huringa nui i roto i te pokey. Ki te pokey whakaingoa o te hydroxypropyl methylcellulose Ko te hua o te huringa o te kukū otinga i runga i te pokey o te otinga ka tino kitea.
3.3 Te hononga i waenga i te potata me te tere kutikuti
Hydroxypropyl methylcellulose wairewa wai he taonga o te kutikuti angiangi. Ko te Hydroxypropyl methylcellulose o te pokey whakaingoa rereke ka rerihia ki te wairewa wai 2%, ka inehia tona pokey i nga reiti kutikuti rereke. Ko nga hua e whai ake nei Ka whakaatuhia i te ahua. I te iti o te kutikuti, kaore i tino rerekee te pokey o te wairewa hydroxypropyl methylcellulose. Na te pikinga o te tere kutikuti, ka tino heke iho te pokey o te wairewa hydroxypropyl methylcellulose me te pokey whakaingoa teitei ake, i te mea kaore i tino heke iho te wairewa whai pokey iti.
3.4 Te hononga i waenga i te pokey me te pāmahana
Ko te pokey o te wairewa hydroxypropyl methylcellulose e tino pa ana ki te pāmahana. Ka piki ake te mahana, ka heke te pokey o te otinga. Ka rite ki te whakaatu i te ahua, ka rite ki te wairewa wai me te kukū o te 2%, ka inehia te huringa o te pokey me te piki o te pāmahana.
3.5 Ētahi atu āhuatanga whakaawe
Ko te viscosity o te wairewa wai o te hydroxypropyl methylcellulose ka pangia ano e nga taapiri i roto i te otinga, te uara pH o te otinga, me te whakahekenga moroiti. I te nuinga o te wa, kia pai ake ai te mahi pokey, hei whakaiti ranei i te utu o te whakamahinga, me taapiri atu nga whakarereketanga rheology, penei i te paru, te paru kua whakarereketia, te paura polymer, te starch ether me te copolymer aliphatic, ki te otinga wai o te hydroxypropyl methylcellulose. , me nga electrolytes penei i te chloride, bromide, phosphate, nitrate, me etahi atu ka taea ano te taapiri ki te wairewa wai. Ko enei taapiri kaore e pa ki nga ahuatanga pokey o te wairewa wai, engari ka pa ki etahi atu waahanga tono o te hydroxypropyl methylcellulose penei i te pupuri wai. , te aukati sag, etc.
Ko te viscosity o te wairewa wai o te hydroxypropyl methylcellulose kaore e pa ana ki te waikawa me te alkali, me te nuinga o te wa e mau ana i roto i te awhe o te 3 ki te 11. Ka taea e ia te tu atu ki etahi momo waikawa ngoikore, penei i te waikawa formic, waikawa acetic, waikawa phosphoric, waikawa boric, waikawa citric, me etahi atu. Engari he iti noa te paanga o te houra, te pāhare pāporo, te wai kotakota, aha atu. Ka whakatauritea ki etahi atu etera cellulose,hydroxypropyl methylcelluloseKo te wairewa wai he pai te pumau antimicrobial, ko te take nui ko te hydroxypropyl methylcellulose he roopu hydrophobic me te nui o te whakakapinga me te aukati i nga roopu Heoi, i te mea kaore i te rite te tauhohenga whakakapi, ka ngawari te whakakore i te waeine anhydroglucose unsubstituted e te microorganisms, ka puta te paheketanga o te ngota ngota ngota me te mekameka sciscellulose ether. Ko te mahi ko te heke o te pokey o te wairewa wai. Mena he mea tika ki te penapena i te wairewa wai o te hydroxypropyl methylcellulose mo te wa roa, e taunaki ana kia taapirihia he tohu o te kaihoko antifungal kia kore ai e tino rerekee te viscosity. I te wa e whiriwhiri ana koe i nga maatete anti-fungal, te whakamarumaru, te patu patu ranei, me whakarongo koe ki te haumaru, me te whiriwhiri i nga hua kaore e paitini ki te tinana o te tangata, he mea pumau me te kore kakara, penei i te AMICAL fungicides a DOW Chem, CANGUARD64, nga huakita FUELSAVER me etahi atu hua. ka taea e koe te mahi i tetahi mahi e rite ana.
Te wa tuku: Apr-28-2024