Kedu ụdị dị iche iche nke hydroxypropyl methylcellulose?

Hydroxypropyl methylcellulose (HPMC)bụ cellulose ether nke na-abụghị nke ionic nke a na-ejikarị eme ihe n'iwu ụlọ, ọgwụ, nri, ihe ịchọ mma na mpaghara ndị ọzọ. E ji cellulose polymer eke mee ya site na iwebata otu ọrụ methoxy (–OCH₃) na hydroxypropoxy (–OCH₂CH(OH)CH₃) site na mmeghachi omume etherification. N'ihi ụdị ihe nnọchi dị iche iche, ogo nnọchi (DS, ogo nnọchi methoxy; MS, ogo nnọchi hydroxypropoxy) na ogo polymerization, enwere ike kewaa HPMC n'ọtụtụ ụdị iji mezuo ihe achọrọ maka ọrụ dị iche iche.

1. Chọpụta site na methoxy na hydroxypropoxy nke nnọchi anya

Ọkwa methoxy na hydroxypropoxy nke nnọchi nke HPMC na-emetụta kpọmkwem mgbaze ya, njikọta okpomọkụ na ọrụ elu.

Ụdị methoxy dị elu HPMC: Ọkwa methoxy nke nnọchi dị elu, ihe ngwọta ahụ nwere gel okpomọkụ siri ike, ma na-emepụta gel kwụsiri ike n'ọnọdụ okpomọkụ dị elu. Ọ dabara adaba maka ihe owuwu ụlọ nke chọrọ idobe mmiri, ịka mma na njikọ, dị ka taịlị gluu, ntụ ntụ putty, na ihe mkpuchi mgbidi mpụta.

Ọkara methoxy-medium hydroxypropoxy HPMC: na-edozi mgbaze na njikọta, nke a na-ejikarị eme ihe na mwepụta ọgwụ, ime ka nri sie ike, wdg.

Obere hydroxypropoxy HPMC dị elu na methoxy: okpomọkụ dị elu na okpomọkụ, ezigbo nghọta ngwọta, viscosity kwụsiri ike, dabara adaba maka ihe ịchọ mma, mmiri anya na ngwa ndị ọzọ chọrọ nnukwu nghọta na obere mgbakasị ahụ.

2. Nhazi site na ọkwa viscosity

A na-egosipụtakarị HPMC site na oke mmiri mmiri nke 2%, site na ole na ole mPa·s ruo 200,000 mPa·s.

Ọbara dị ala (3–100 mPa·s): ezigbo mmiri mmiri, nke a na-ejikarị eme ihe n'oge ndị chọrọ mgbaze na ntinye ngwa ngwa, dịka mkpuchi ọgwụ, ịgba mmiri na ihe ndị na-eme ka emulsion sie ike.

Ọkara viscosity (100–10,000 mPa·s): eji arụ ụlọ slaịta na ngwaahịa gypsum, na-eburu n'uche ma mmiri na ihe owuwu.

Nnukwu viscosity (10,000–200,000 mPa·s): ike ijide mmiri na ikike ime ka ọ sie ike, nke a na-ejikarị eme ihe na taịlị, ngwaahịa mado, kemịkalụ kwa ụbọchị na ihe ndị na-eme ka nri sie ike.

3. Nhazi site na njirimara mgbaze na ụdị ion

HPMC bụ cellulose ether na-abụghị ionic, nwere ezigbo mmiri na-agbaze ma kwụsie ike na electrolytes. A na-agbanwe ụfọdụ ngwaahịa ka ha dabara na ngwa pụrụ iche:

HPMC nke na-agbaze ngwa ngwa: Mgbe a gwọchara ya n'elu, a pụrụ ịgbasa ya ngwa ngwa na mmiri oyi iji mepụta otu ihe ngwọta, nke dabara maka nkwadebe ngwa ngwa nke ngwa agha ma ọ bụ mkpuchi.

HPMC nke na-agbaze nwayọ nwayọ: Ọsọ mgbaze ahụ na-adị nwayọ nwayọ, ọ dị mma maka izere njikọta na gburugburu ebe okpomọkụ dị elu, a na-ejikarị ya eme ihe maka ngwakọta buru ibu na ebe a na-ewu ụlọ.

4. Nhazi site na mgbanwe ọrụ

Dịka mkpa njedebe si dị, enwere ike ịgbanwe HPMC n'ọtụtụ ụzọ ọrụ dị iche iche:

HPMC nke na-eguzogide enzyme: Ọ na-enwe nkwụsi ike ka mma na gburugburu ebe nje bacteria na-arụ ọrụ ma a na-eji ya maka nri na ihe ndị dị ndụ kpọmkwem.

HPMC nke na-eguzogide okpomọkụ dị elu: Ọ na-ejigide okpomọkụ dị elu nke gelation iji melite nrapado na njigide mmiri n'oge owuwu okpomọkụ dị elu.

HPMC nke e ji Surfactant mee ka ọ dịkwuo mma: Ọ na-eme ka emulsion kwụsie ike ma na-eme ka mmiri dị mmiri, nke a na-eji na agba na mkpuchi latex.

5. Ụdị ahaziri iche site na mpaghara ngwa

HPMC nke ọkwa ụlọ: Na-emesi ike idobe mmiri, arụmọrụ owuwu, mgbochi mmịpụ na njikọta, nke a na-eji na taịlị, putties, gypsum, na moto mkpuchi okpomọkụ.

HPMC nke ọkwa ọgwụ: Ọ na-emezu ụkpụrụ pharmacopoeia, nke e ji mee ihe mkpuchi mbadamba, ihe ndị na-ebu ọgwụ na-adịgide adịgide, na ihe ndị na-eme ka anya dị arọ.

Nri HPMC: A na-eji ya eme ihe dị ka ihe na-eme ka ọ sie ike, ihe na-eme ka ọ dị nro, na ihe nnọchi abụba, a na-ejikarị ya eme ihe n'ime achịcha na ngwaahịa mmiri ara ehi.

HPMC nke ọkwa ịchọ mma: Ọ na-edo anya nke ọma, anaghị akpasu iwe, a na-eji ya na shampoo, ude mmiri, na ihe mkpuchi ihu.

A na-ekpebi ụdị HPMC site na ogo mgbanwe methoxy na hydroxypropoxy, ogo nke polymerization, na mgbanwe emechara. Ụdị dị iche iche nwere uru nke ha na viscosity, okpomọkụ gelation okpomọkụ, njigide mmiri, ọnụego mgbasa, na ọnọdụ ngwa. Ịhọrọ ụdị kwesịrị ekwesịHPMC chọrọ ịtụle ihe achọrọ maka ngwa kpọmkwem, dịka ihe achọrọ maka ihe owuwu maka idobe mmiri na ihe owuwu, ihe achọrọ maka ọgwụ maka nchekwa na ihe mgbaze, yana ihe achọrọ maka nri na kemịkalụ kwa ụbọchị maka nghọta na uto.