I-Hydroxypropyl methylcellulose (HPMC)iwukuphuma kwe-cellulose okuvame ukusetshenziswa okunezinhlobonhlobo zezicelo, ikakhulukazi emikhakheni yezemithi, izimonyo, ukudla, nezinto zokwakha. Akuyona i-solvent, kodwa i-polymer encibilikayo emanzini engancibilika emanzini futhi yakhe isixazululo se-colloidal esobala. Ukunyibilika kwe-AnxinCel®HPMC kuncike enanini nendawo ye-methyl kanye ne-hydroxypropyl esikhundleni sesakhiwo sayo samangqamuzana.
1. Izakhiwo eziyisisekelo ze-hydroxypropyl methylcellulose
IHydroxypropyl methylcellulose itholakala nge-methylation kanye ne-hydroxypropylation ye-cellulose. I-Cellulose ngokwayo iyi-polysaccharide ephezulu yemvelo etholakala ezindongeni zamaseli ezitshalo. Isakhiwo samakhemikhali se-HPMC ikakhulukazi sakhiwe amayunithi e-glucose, okungama-molecule amaketanga amade axhunywe ngamabhondi e-β-1,4 glycosidic. Kulesi sakhiwo samangqamuzana, amanye amaqembu e-hydroxyl athathelwa indawo yi-methyl (-OCH₃) ne-hydroxypropyl (-C₃H₇OH), eyinikeza ukuncibilika okuhle nezinye izakhiwo zomzimba namakhemikhali.
I-solubility ye-HPMC ithintwa ukwakheka kwamangqamuzana futhi ngokuvamile inezici ezilandelayo:
Ukunyibilika kwamanzi: I-HPMC ingakha isixazululo se-viscous emanzini futhi incibilike ngokushesha. Ukunyibilika kwayo kuhlobene eduze nezinga lokushisa lamanzi kanye nesisindo samangqamuzana e-HPMC.
I-viscosity ephezulu: Ekugxiliseni okuthile, isisombululo se-HPMC sibonisa i-viscosity ephakeme, ikakhulukazi esisindweni samangqamuzana aphezulu kanye nokugxila okuphezulu.
Ukuzinza okushisayo: I-HPMC inokuqina okuhle ebangeni elithile lamazinga okushisa futhi akulula ukubola, ngakho-ke inezinzuzo ezithile kunqubo yokucubungula okushisayo.
2. Ukunyibilika kwe-HPMC
I-HPMC iwuketshezi oluncibilikayo emanzini, kodwa ayincibilikisiwe yizo zonke izincibilikisi. Ukuziphatha kwayo kokuhlakazeka kuhlobene ne-polarity yesinyibiliki kanye nokuxhumana phakathi kwama-athomu nama-molecule e-HPMC.
Amanzi: I-HPMC ingancibilika emanzini. Amanzi ayincibilikisi yawo evame kakhulu, futhi phakathi nenqubo yokuhlakazwa, ama-molecule e-AnxinCel®HPMC azokwakha amabhondi e-hydrogen nama-molecule amanzi ukuze afinyelele ukuhlakazeka. Izinga lokuqedwa lithintwa izici ezifana nesisindo samangqamuzana e-HPMC, izinga le-methylation ne-hydroxypropylation, izinga lokushisa, nenani le-pH lamanzi. Ngokuvamile, ukunyibilika kwe-HPMC kuhamba phambili endaweni engathathi hlangothi ye-pH.
Izinyibilikisi zemvelo: I-HPMC cishe ayincibiliki kuzincibilikisi eziningi eziphilayo, njengotshwala, ama-ether, nama-hydrocarbon. Lokhu kungenxa yokuthi ukwakheka kwayo kwamangqamuzana kuqukethe amaqembu e-hydrophilic hydroxyl kanye namaqembu e-lipophilic methyl kanye ne-hydroxypropyl. Nakuba inobudlelwane obuqinile bamanzi, ayihambisani kahle nezincibilikizeli eziningi eziphilayo.
Ukunyibilika kwamanzi ashisayo: Emanzini afudumele (imvamisa engu-40°C kuya ku-70°C), i-HPMC incibilika ngokushesha futhi isixazululo esincibilikisiwe sibonisa i-viscosity ephezulu. Njengoba izinga lokushisa liqhubeka likhula, izinga lokuqedwa kanye ne-solubility lizokhula, kodwa emazingeni okushisa aphezulu kakhulu, i-viscosity yesisombululo ingathinteka.
3. Ukusetshenziswa kwe-HPMC
Ngenxa yokuncibilika kahle kwamanzi, ubuthi obuphansi, kanye ne-viscosity eguquguqukayo, i-HPMC isetshenziswa kabanzi ezimbonini ezihlukahlukene.
Imboni yezemithi: Embonini yezemithi, i-HPMC isetshenziswa kakhulu ekulungiseleleni ukukhishwa okuqhubekayo kwezidakamizwa, ukubumba amaphilisi, amajeli, nabathwali bezidakamizwa. Kungasiza izidakamizwa zincibilike ngokuzinzile emanzini futhi zilawule izinga lokukhishwa kwezidakamizwa.
Imboni yokudla: I-HPMC, njengesengezo sokudla, ivamise ukusetshenziselwa ukuhlanganisa, ukujiya, nokuthambisa. Ezimpahleni ezibhakwayo, kungathuthukisa i-ductility nokuzinza kwenhlama. I-HPMC ijwayele ukusetshenziswa ku-ayisikhilimu, iziphuzo kanye nokudla okunamafutha aphansi.
Imboni yezokwakha: Embonini yezokwakha, i-HPMC ivamise ukusetshenziswa njengesigqinsi sokwakha udaka, olungathuthukisa ukusebenza kokwakha, ukugcinwa kwamanzi namandla okubopha udaka.
Izimonyo: Ezimonyoni, i-AnxinCel®HPMC isetshenziswa kakhulu njenge-thickener, i-ejenti emisa okwesikhashana kanye nesiqinisi, futhi isetshenziswa kakhulu emikhiqizweni efana namakhilimu obuso, ama-shampoos, namajeli eshawa.
I-HPMCiwukuphuma kwe-cellulose encibilikayo emanzini futhi i-viscous kakhulu engakha isisombululo se-colloidal esisobala emanzini. Akuyona i-solvent, kodwa inhlanganisela ye-molecular ephezulu engancibilika emanzini. Ukunyibilika kwayo kubonakala ngokuncibilika okuhle emanzini, kodwa okungancibiliki kakhulu kuzincibilikisi eziningi eziphilayo. Lezi zici ze-HPMC ziyenza isetshenziswe kabanzi ezimbonini eziningi, okuhlanganisa ezemithi, ukudla, ezokwakha, nezimonyo.
Isikhathi sokuthumela: Feb-17-2025