I-HPMC VS HEC: Umehluko O-6 Okufanele Uwazi!

Yethula:

I-Hydroxypropylmethylcellulose (HPMC) kanye ne-hydroxyethylcellulose (HEC) zombili ziyizithasiselo ezisetshenziswa kakhulu embonini yokudla, yezimonyo kanye neyemithi. Lezi zinto ezitholakala ku-cellulose zinamathuba amaningi okusetshenziswa ngenxa yokuncibilika kwazo emanzini okuhlukile, ukuqina kokujiya, kanye nekhono elihle kakhulu lokwenza ifilimu.

1. Isakhiwo samakhemikhali:

I-HPMC iyi-polymer yokwenziwa etholakala ku-cellulose. Yenziwa ngokushintsha i-cellulose yemvelo ngamakhemikhali ngokufaka i-propylene oxide kanye ne-methyl chloride. I-HEC nayo iwuhlobo lwe-cellulose derivative, kodwa yenziwa ngokushintsha i-cellulose yemvelo nge-ethylene oxide bese iyiphatha nge-alkali.

2. Ukuncibilika:

Kokubili i-HPMC ne-HEC kuyancibilika emanzini futhi kungancibilika emanzini abandayo. Kodwa ukuncibilika kwe-HEC kuphansi kune-HPMC. Lokhu kusho ukuthi i-HPMC inokuncibilika okungcono futhi ingasetshenziswa kalula ekwakhiweni.

3. Ukujiya:

I-HPMC kanye ne-HEC zinezici ezihlukile ze-viscosity ngenxa yezakhiwo zazo zamakhemikhali. I-HEC inesisindo sama-molecule esiphezulu kanye nesakhiwo esiminyene kune-HPMC, okwenza ibe ne-viscosity ephezulu. Ngakho-ke, i-HEC ivame ukusetshenziswa njengesithambisi ekwakhiweni okudinga i-viscosity ephezulu, kuyilapho i-HPMC isetshenziswa ekwakhiweni okudinga i-viscosity ephansi.

4. Ukusebenza kokwakha amafilimu:

Kokubili i-HPMC ne-HEC zinekhono elihle kakhulu lokwenza ifilimu. Kodwa i-HPMC inezinga lokushisa eliphansi lokwenza ifilimu, okusho ukuthi ingasetshenziswa emazingeni okushisa aphansi. Lokhu kwenza i-HPMC ifaneleke kakhulu ukusetshenziswa ekwakhiweni okudinga izikhathi zokomisa ngokushesha kanye nokunamathela okungcono.

5. Ukuqina:

I-HPMC kanye ne-HEC zizinzile ngaphansi kwezimo eziningi ze-pH kanye nokushisa. Kodwa-ke, i-HEC ibucayi kakhulu ekushintsheni kwe-pH kune-HPMC. Lokhu kusho ukuthi i-HEC kufanele isetshenziswe ekwakhiweni okune-pH engu-5 kuya ku-10, kuyilapho i-HPMC ingasetshenziswa ebangeni le-pH elibanzi.

6. Isicelo:

Izici ezahlukene ze-HPMC kanye ne-HEC zizenza zifaneleke ukusetshenziswa okuhlukene. I-HEC ivame ukusetshenziswa njenge-ejenti yokujiya ekwakhiweni kwezimonyo kanye nemithi. Iphinde isetshenziswe njenge-ejenti yokubopha kanye nokwenza ifilimu ekwakhiweni kwamaphilisi. I-HPMC isetshenziswa njenge-ejenti yokujiya, yokuzinzisa, kanye ne-ejenti yokwenza ifilimu ekudleni, emithini, kanye nakwezimonyo. Iphinde isetshenziswe njenge-ejenti yokujiya kwezinye izinhlelo zokusebenza zokudla.

Ekuphetheni:

I-HPMC kanye ne-HEC zombili ziyi-cellulose derivatives ezinezakhiwo ezihlukile ezifanele ukusetshenziswa okuhlukene. Ukuqonda umehluko phakathi kwalezi zithasiselo ezimbili kungakusiza ukhethe esifanele iresiphi yakho. Sekukonke, i-HPMC kanye ne-HEC ziyizithasiselo eziphephile nezisebenzayo ezinikeza izinzuzo eziningi embonini yokudla, yezimonyo kanye neyemithi.