I-Putty iyimpahla ebalulekile yokwakha esetshenziselwa ukulinganisa udonga, futhi ukusebenza kwayo kuthinta ngokuqondile ukunamathela kopende kanye nekhwalithi yokwakha. Ekwakhiweni kwe-putty, izithasiselo ze-cellulose ether zidlala indima ebalulekile.IHydroxypropyl Methylcellulose (HPMC), njengenye ye-cellulose ethers esetshenziswa kakhulu, ingathuthukisa ngokuphumelelayo i-viscosity, ukusebenza kokwakhiwa kanye nokuzinza kwesitoreji se-putty.
1. Izakhiwo eziyisisekelo ze-Hydroxypropyl Methylcellulose
I-HPMC iyi-polymer engeyona i-ionic encibilika emanzini enokuqina okuhle, ukugcinwa kwamanzi, ukuhlakazeka, i-emulsification kanye nezakhiwo zefilimu. I-viscosity yayo ithintwa izinga lokushintshwa, izinga le-polymerization kanye nezimo zokuncibilika. Isixazululo esinamanzi se-AnxinCel®HPMC sibonisa izici zoketshezi lwe-pseudoplastic, okungukuthi, lapho izinga le-shear likhuphuka, i-viscosity yesisombululo iyancipha, okubalulekile ekwakhiweni kwe-putty.
2. Umthelela we-HPMC ku-putty viscosity
2.1 Ukuqina komphumela
I-HPMC yakha isisombululo se-viscosity esiphezulu ngemva kokuncibilika emanzini. Umphumela wayo wokujiya ubonakala ngokuyinhloko kulezi zici ezilandelayo:
Ukuthuthukisa i-thixotropy ye-putty: I-HPMC ingagcina i-putty i-viscosity ephezulu uma imile ukuze igweme ukuwohloka, futhi inciphise i-viscosity lapho ikhuhla futhi ithuthukisa ukusebenza kokwakha.
Ukuthuthukisa ukusebenza kwe-putty: Inani elifanele le-HPMC lingathuthukisa ukuthambisa kwe-putty, lenze ukukhuhla kube bushelelezi futhi kunciphise ukumelana nokwakhiwa.
Okuthinta amandla okugcina e-putty: Umthelela wokujiya we-HPMC wenza okokugcwalisa kanye nezinto zikasimende ku-putty zihlakazeke ngokulinganayo, kugwenywe ukuhlukaniswa kanye nokwenza ngcono ukusebenza kokuqina ngemva kokwakhiwa.
2.2 Umthelela enqubweni ye-hydration
I-HPMC inezinto ezinhle kakhulu zokugcina amanzi, ezinganciphisa ukuhwamuka okusheshayo kwamanzi ongqimbeni lwe-putty, ngaleyo ndlela kwandise isikhathi sokugeleza kwe-putty esekwe usimende futhi kuthuthukise amandla nokumelana nokuqhekeka kwe-putty. Kodwa-ke, i-viscosity ephezulu kakhulu ye-HPMC izothinta ukungena komoya kanye nesivinini sokumisa se-putty, okuholela ekunciphiseni ukusebenza kahle kokwakhiwa. Ngakho-ke, inani le-HPMC lidinga ukuqinisekisa ukusebenza ngenkathi igwema imiphumela emibi ngesikhathi sokuqina.
2.3 Ubudlelwano phakathi kwesisindo semolekyuli ye-HPMC kanye ne-viscosity ye-putty
Ukuphakama kwesisindo samangqamuzana e-HPMC, kulapho i-viscosity yesisombululo sayo esinamanzi sikhulu. Ku-putty, ukusetshenziswa kwe-HPMC ene-viscosity ephezulu (efana nohlobo olune-viscosity enkulu kuno-100,000 mPa·s) kungathuthukisa kakhulu ukugcinwa kwamanzi kanye nezindawo zokulwa nokugoqa kwe-putty, kodwa kungase futhi kuholele ekwehleni kokusebenza. Ngakho-ke, ngaphansi kwezidingo ezahlukene zokwakha, i-HPMC ene-viscosity efanelekile kufanele ikhethwe ukulinganisa ukugcinwa kwamanzi, ukusebenza nokusebenza kokugcina.
2.4 Umthelela womthamo we-HPMC ku-putty viscosity
Inani le-AnxinCel®HPMC elingeziwe linomthelela omkhulu ku-viscosity ye-putty, futhi umthamo uvame ukuba phakathi kuka-0.1% no-0.5%. Uma umthamo we-HPMC uphansi, umphumela wokujiya ku-putty unomkhawulo, futhi ungase ungakwazi ukuthuthukisa ngempumelelo ukusebenza nokugcinwa kwamanzi. Uma umthamo uphezulu kakhulu, i-viscosity ye-putty inkulu kakhulu, ukumelana nokwakhiwa kuyanda, futhi kungase kuthinte isivinini sokumisa se-putty. Ngakho-ke, kuyadingeka ukukhetha inani elifanele le-HPMC ngokuya ngefomula ye-putty kanye nemvelo yokwakha.
I-Hydroxypropyl methylcellulose idlala indima ekuqiniseni, ekugcinweni kwamanzi nasekuthuthukiseni ukusebenza kwe-putty. Isisindo se-molecular, degree of substitution kanye nenani lokwengeza leI-HPMCizothinta i-viscosity ye-putty. Inani elifanele le-HPMC lingathuthukisa ukusebenza nokumelana namanzi kwe-putty, kuyilapho ukwengeza ngokweqile kungase kwandise ubunzima bokwakha. Ngakho-ke, ekusetshenzisweni kwangempela kwe-putty, izici ze-viscosity nezidingo zokwakha ze-HPMC kufanele zicatshangelwe ngokugcwele, futhi ifomula kufanele ilungiswe ngokunengqondo ukuze kutholwe ukusebenza okuhle kakhulu kokwakha kanye nekhwalithi yokugcina.
Isikhathi sokuthumela: Feb-10-2025