IHydroxypropyl methylcellulose (HPMC)yinto eqhelekileyo ephuma kwiselulosi enoluhlu olubanzi lwezicelo, ngakumbi kwiinkalo zamayeza, izinto zokuthambisa, ukutya, kunye nezinto zokwakha. Akusiyo i-solvent, kodwa i-polymer e-soluble yamanzi enokuthi inyibilike emanzini kwaye yenze isisombululo se-colloidal esicacileyo. I-solubility ye-AnxinCel®HPMC ixhomekeke kwinani kunye nendawo ye-methyl kunye ne-hydroxypropyl substituents kwisakhiwo sayo se-molecular.
1. Iimpawu ezisisiseko ze-hydroxypropyl methylcellulose
I-Hydroxypropyl methylcellulose ifumaneka nge-methylation kunye ne-hydroxypropylation ye-cellulose. I-Cellulose ngokwayo yipolysaccharide ephezulu yendalo ekhoyo kwiindonga zeeseli zesityalo. Ubume bemichiza ye-HPMC ubukhulu becala buqulunqwe ngeeyunithi ze-glucose, eziziimolekyuli ezinde ezidityaniswe yi-β-1,4 glycosidic bond. Kwesi sakhiwo seemolekyuli, amanye amaqela e-hydroxyl athatyathelwa indawo yi-methyl (-OCH₃) kunye ne-hydroxypropyl (-C₃H₇OH), inika ukunyibilika kakuhle kunye nezinye izinto ezibonakalayo kunye neekhemikhali.
I-solubility ye-HPMC ichatshazelwa yi-molecular structure kwaye ihlala inezi mpawu zilandelayo:
Ukunyibilika kwamanzi: I-HPMC inokwenza isisombululo se-viscous emanzini kwaye inyibilika ngokukhawuleza. Ukunyibilika kwayo kuhambelana ngokusondeleyo nobushushu bamanzi kunye nobunzima bemolekyuli yeHPMC.
I-viscosity ephezulu: Kugxininiso oluthile, isisombululo se-HPMC sibonisa i-viscosity ephezulu, ngakumbi kwi-molecular weight and concentration ephezulu.
Uzinzo lwe-Thermal: I-HPMC inozinzo oluhle kuluhlu oluthile lwamaqondo obushushu kwaye akukho lula ukubola, ngoko luneenzuzo ezithile kwinkqubo yokucubungula i-thermal.
2. Ukunyibilika kwe-HPMC
I-HPMC yinto enyibilikayo emanzini, kodwa ayinyibilikiswa zizo zonke izinyibilikisi. Ukuziphatha kwayo kokutshatyalaliswa kuhambelana ne-polarity ye-solvent kunye nokusebenzisana phakathi kwee-molecule ze-solvent kunye nee-molecule ze-HPMC.
Amanzi: I-HPMC inokunyibilika emanzini. Amanzi yi-solvent yayo eqhelekileyo, kwaye ngexesha lenkqubo yokuchithwa, i-AnxinCel®HPMC iamolekyu ziya kwenza iibhondi ze-hydrogen kunye neemolekyuli zamanzi ukuphumeza ukuchithwa. Iqondo lokuchithwa lichaphazeleka yizinto ezifana nobunzima bemolekyuli ye-HPMC, iqondo le-methylation kunye ne-hydroxypropylation, ubushushu, kunye nexabiso le-pH yamanzi. Ngokwesiqhelo, ukunyibilika kwe-HPMC yeyona nto ilungileyo kwindawo engathathi hlangothi ye-pH.
Izinyibilikisi ze-Organic: I-HPMC iphantse yanganyibiliki kwizinyibilikisi ezininzi zezinto eziphilayo, ezinjengeealkoholi, ii-ethers, kunye neehydrocarbons. Oku kungenxa yokuba isakhiwo sayo se-molecular iqukethe amaqela e-hydrophilic hydroxyl kunye ne-lipophilic methyl kunye namaqela e-hydroxypropyl. Nangona inobudlelwane obuqinileyo namanzi, ayihambelani kakuhle nezinyibilikisi ezininzi zendalo.
Ukunyibilika kwamanzi ashushu: Kumanzi afudumeleyo (ngokuqhelekileyo i-40 ° C ukuya ku-70 ° C), i-HPMC ichithwa ngokukhawuleza kwaye isisombululo esinyibilikileyo sibonisa i-viscosity ephezulu. Njengoko iqondo lokushisa likhula ngakumbi, izinga lokuchithwa kunye ne-solubility liya kwanda, kodwa kwiqondo lokushisa eliphezulu kakhulu, i-viscosity yesisombululo inokuchaphazeleka.
3. Ukusetyenziswa kweHPMC
Ngenxa yokunyibilika kakuhle kwamanzi, ubutyhefu obuphantsi, kunye ne-viscosity eguquguqukayo, i-HPMC isetyenziswa kakhulu kumashishini ahlukeneyo.
Umzi-mveliso wamachiza: Kwishishini lamachiza, i-HPMC isetyenziswa ngokubanzi kumalungiselelo okukhutshwa okuzinzileyo kwamachiza, ukubumba ithebhulethi, iijeli, kunye nabathwali beziyobisi. Inokunceda amachiza anyibilike ngokuzinzileyo emanzini kwaye alawule izinga lokukhutshwa kwechiza.
Umzi-mveliso wokutya: I-HPMC, njengesongezo sokutya, iqhele ukusetyenziswa kwi-emulsification, ukujiya, kunye nokuthambisa. Kwiimpahla ezibhakiweyo, inokuphucula i-ductility kunye nokuzinza kwentlama. I-HPMC ikwasetyenziswa ngokuqhelekileyo kwi-ayisikrimu, iziselo kunye nokutya okunamafutha aphantsi.
Umzi-mveliso wokwakha: Kushishino lokwakha, i-HPMC isoloko isetyenziswa njenge-thickener yokwakha udaka, enokuphucula ukusebenza kolwakhiwo, ukugcinwa kwamanzi kunye namandla okubopha udaka.
Izinto zokuthambisa: Kwizinto zokuthambisa, i-AnxinCel®HPMC isetyenziswa ikakhulu njengento etyebisayo, i-arhente exhomayo kunye nezinzisi, kwaye isetyenziswa kakhulu kwiimveliso ezifana neekhrimu zobuso, iishampu, kunye nejeli zeshawa.
HPMCyinto enyibilikayo yamanzi kunye ne-viscous cellulose derivative enokuthi yenze isisombululo se-colloidal esicacileyo emanzini. Ayisiyonto enyibilikayo, kodwa iphezulu i-molecular compound enokunyibilika emanzini. Ukunyibilika kwayo kubonakaliswa ikakhulu kunyibiliko olulungileyo emanzini, kodwa alunakunyibilika kuninzi lwezinyibilikisi zendalo. Ezi mpawu ze-HPMC zenza ukuba isetyenziswe ngokubanzi kumashishini amaninzi, kubandakanywa amayeza, ukutya, ukwakhiwa, kunye nezithambiso.
Ixesha lokuposa: Feb-17-2025