Hydroxypropyl methylcellulose (HPMC)ke motsoako oa selulose o sebelisoang hangata o nang le mefuta e mengata ea ts'ebeliso, haholo-holo mafapheng a meriana, litlolo, lijo le thepa ea ho haha. Ha se solvent, empa ke polymer e qhibilihang ka metsi e ka qhibilihang ka metsing 'me ea etsa tharollo e hlakileng ea colloidal. Ho qhibiliha ha AnxinCel®HPMC ho itšetlehile ka palo le boemo ba li-substituent tsa methyl le hydroxypropyl mohahong oa eona oa limolek'hule.
1. Lintho tsa motheo tsa hydroxypropyl methylcellulose
Hydroxypropyl methylcellulose e fumanoa ka methylation le hydroxypropylation ea selulose. Cellulose ka boeona ke polysaccharide ea tlhaho e phahameng ea molek'hule e teng marakong a lisele tsa semela. Sebopeho sa lik'hemik'hale tsa HPMC haholo-holo se entsoe ka likaroloana tsa tsoekere, e leng limolek'hule tsa ketane e telele tse hokahaneng ka β-1,4 glycosidic bond. Sebopehong sena sa limolek'hule, lihlopha tse ling tsa hydroxyl li nkeloa sebaka ke methyl (-OCH₃) le hydroxypropyl (-C₃H₇OH), e leng se fanang ka ho qhibiliha hantle le lisebelisoa tse ling tsa 'mele le tsa lik'hemik'hale.
The solubility ea HPMC e angoa ke sebopeho sa limolek'hule mme hangata e na le litšobotsi tse latelang:
Ho qhibiliha ha metsi: HPMC e ka etsa tharollo ea viscous ka metsing 'me ea qhibiliha kapele. Solubility ea eona e amana haufi-ufi le mocheso oa metsi le boima ba limolek'hule tsa HPMC.
Viscosity e phahameng: Ka nako e itseng, tharollo ea HPMC e bonts'a viscosity e phahameng, haholo-holo boima ba limolek'hule le khatello e phahameng.
Ho tsitsa ha mocheso: HPMC e na le botsitso bo botle maemong a itseng a mocheso 'me ha ho bonolo ho senya, kahoo e na le melemo e itseng ts'ebetsong ea mocheso oa mocheso.
2. Sollubility ea HPMC
HPMC ke ntho e qhibilihang ka metsing, empa ha e qhibilihe ke metsoako eohle. Boitšoaro ba eona ba ho qhibiliha bo amana le polarity ea solvent le tšebelisano pakeng tsa limolek'hule tsa solvent le limolek'hule tsa HPMC.
Metsi: HPMC e ka qhibiliha ka metsing. Metsi ke motsoako oa oona o tloaelehileng ka ho fetisisa, 'me nakong ea ts'ebetso ea ho qhibiliha, limolek'hule tsa AnxinCel®HPMC li tla theha likamano tsa hydrogen le limolek'hule tsa metsi ho finyella ho qhibiliha. Tekanyo ea ho qhibiliha e angoa ke lintlha tse kang boima ba limolek'hule tsa HPMC, tekanyo ea methylation le hydroxypropylation, mocheso, le pH boleng ba metsi. Hangata, ho qhibiliha ha HPMC ho molemo ka ho fetisisa tikolohong ea pH e sa nke lehlakore.
Organic solvents: HPMC e batla e sa qhibilihe ka har'a metsoako e mengata ea tlhaho, joalo ka joala, ethers, le hydrocarbons. Lebaka ke hobane sebopeho sa eona sa limolek'hule se na le lihlopha tsa hydrophilic hydroxyl le lihlopha tsa lipophilic methyl le hydroxypropyl. Leha e na le kamano e matla ea metsi, ha e tsamaellane hantle le lihlapolli tse ngata tsa tlhaho.
Ho qhibiliha ha metsi a chesang: Ka metsing a futhumetseng (hangata 40 ° C ho 70 ° C), HPMC e qhibiliha ka potlako 'me tharollo e qhibilihisitsoeng e bontša viscosity e phahameng. Ha mocheso o ntse o eketseha, tekanyo ea ho qhibiliha le ho qhibiliha ho tla eketseha, empa ka mocheso o phahameng haholo, viscosity ea tharollo e ka ameha.
3. Tšebeliso ea HPMC
Ka lebaka la ho qhibiliha ha eona hantle ha metsi, chefo e tlase, le viscosity e feto-fetohang, HPMC e sebelisoa haholo liindastering tse fapaneng.
Indasteri ea meriana: Indastering ea meriana, HPMC e sebelisoa haholo litokisetsong tsa nako e telele tsa tokollo ea lithethefatsi, ho bopa matlapa, li-gel le bajari ba lithethefatsi. E ka thusa lithethefatsi ho qhibiliha ka mokhoa o tsitsitseng metsing le ho laola sekhahla sa ho lokolloa ha lithethefatsi.
Indasteri ea lijo: HPMC, joalo ka tlatsetso ea lijo, hangata e sebelisoa bakeng sa emulsification, thickening, le moisturizing. Ka thepa e halikiloeng, e ka ntlafatsa ductility le botsitso ba hlama. HPMC e boetse e sebelisoa ka tloaelo ho ice cream, lino le lijo tse nang le mafura a tlaase.
Indasteri ea kaho: Lefapheng la kaho, HPMC e atisa ho sebelisoa e le motenya bakeng sa ho haha seretse, se ka ntlafatsang ts'ebetso ea kaho, ho boloka metsi le matla a tlamahano a seretse.
Litlolo: Ka litlolo, AnxinCel®HPMC e sebelisoa haholo-holo e le ntho e teteaneng, e emisang le ho tsitsisa, 'me e sebelisoa haholo lihlahisoa tse kang litlolo tsa sefahleho, li-shampoo le li-gels tsa shaoara.
HPMCke motsoako oa selulose o qhibilihang ka metsing le o nang le viscous haholo o ka etsang tharollo e hlakileng ea colloidal metsing. Ha se mokelikeli, empa ke motsoako o phahameng oa limolek'hule o ka qhibilihang ka metsing. Ho qhibiliha ha eona ho bonahala haholo ka ho qhibiliha ha metsi ka metsing, empa ha ho qhibilihe ka har'a metsoako e mengata ea manyolo. Litšobotsi tsena tsa HPMC li etsa hore e sebelisoe haholo liindastering tse ngata, ho kenyeletsoa meriana, lijo, kaho le litlolo.
Nako ea poso: Feb-17-2025