Hydroxypropyl methylcellulose (HPMC)ndi chochokera ku cellulose chomwe chimagwiritsidwa ntchito mosiyanasiyana, makamaka pankhani yazamankhwala, zodzola, chakudya, ndi zomangira. Sizosungunulira, koma polima osungunuka m'madzi omwe amatha kusungunuka m'madzi ndikupanga njira yowonekera ya colloidal. Kusungunuka kwa AnxinCel®HPMC kumadalira chiwerengero ndi malo a methyl ndi hydroxypropyl m'malo mwa maselo ake.
1. Zinthu zoyambira za hydroxypropyl methylcellulose
Hydroxypropyl methylcellulose imapezeka ndi methylation ndi hydroxypropylation ya cellulose. Ma cellulose pawokha ndi polysaccharide yachilengedwe yapamwamba kwambiri yomwe imapezeka m'makoma a cell cell. Kapangidwe kakemidwe ka HPMC kumapangidwa makamaka ndi mayunitsi a shuga, omwe ndi mamolekyu atalitali olumikizidwa ndi β-1,4 glycosidic bond. M'maselo a maselowa, magulu ena a hydroxyl amasinthidwa ndi methyl (-OCH₃) ndi hydroxypropyl (-C₃H₇OH), kuwapatsa kusungunuka kwabwino ndi zinthu zina zakuthupi ndi mankhwala.
Kusungunuka kwa HPMC kumakhudzidwa ndi kapangidwe ka maselo ndipo nthawi zambiri kumakhala ndi izi:
Kusungunuka kwamadzi: HPMC imatha kupanga yankho la viscous m'madzi ndikusungunuka mwachangu. Kusungunuka kwake kumagwirizana kwambiri ndi kutentha kwa madzi ndi kulemera kwa maselo a HPMC.
Kukhuthala kwakukulu: Pazigawo zina, yankho la HPMC limasonyeza kukhuthala kwapamwamba, makamaka pa kulemera kwakukulu kwa maselo ndi ndende yaikulu.
Kukhazikika kwamafuta: HPMC ili ndi kukhazikika kwabwino pamitundu ina ya kutentha ndipo sikophweka kuwola, kotero ili ndi zabwino zina munjira yopangira matenthedwe.
2. Kusungunuka kwa HPMC
HPMC ndi madzi sungunuka mankhwala, koma si kusungunuka ndi zosungunulira zonse. Kusungunuka kwake kumakhudzana ndi polarity ya zosungunulira komanso kuyanjana pakati pa mamolekyu osungunulira ndi mamolekyu a HPMC.
Madzi: HPMC ikhoza kusungunuka m'madzi. Madzi ndiye chosungunulira chake chofala kwambiri, ndipo pakutha, mamolekyu a AnxinCel®HPMC amapanga zomangira za haidrojeni ndi mamolekyu amadzi kuti akwaniritse kusungunuka. Kuchuluka kwa kusungunuka kumakhudzidwa ndi zinthu monga kulemera kwa maselo a HPMC, digiri ya methylation ndi hydroxypropylation, kutentha, ndi pH mtengo wa madzi. Nthawi zambiri, kusungunuka kwa HPMC ndikwabwino kwambiri m'malo osalowerera pH.
Organic solvents: HPMC ndi pafupifupi osasungunuka mu zosungunulira zambiri organic, monga alcohols, etha, ndi hydrocarbons. Izi ndichifukwa choti ma cell ake amakhala ndi magulu a hydrophilic hydroxyl ndi magulu a lipophilic methyl ndi hydroxypropyl. Ngakhale ili ndi mgwirizano wamphamvu wamadzi, imagwirizana bwino ndi zosungunulira zambiri za organic.
Kusungunuka kwamadzi otentha: M'madzi ofunda (nthawi zambiri 40 ° C mpaka 70 ° C), HPMC imasungunuka mwamsanga ndipo yankho losungunuka limasonyeza kukhuthala kwakukulu. Pamene kutentha kumawonjezeka, kuchuluka kwa kusungunuka ndi kusungunuka kudzawonjezeka, koma pa kutentha kwakukulu, kukhuthala kwa yankho kungakhudzidwe.
3. Kugwiritsa ntchito HPMC
Chifukwa cha kusungunuka kwake kwamadzi bwino, kawopsedwe kakang'ono, ndi kukhuthala kosinthika, HPMC imagwiritsidwa ntchito kwambiri m'mafakitale osiyanasiyana.
Makampani opanga mankhwala: M'makampani opanga mankhwala, HPMC imagwiritsidwa ntchito kwambiri pokonzekera kumasulidwa kosalekeza kwa mankhwala, kuumba mapiritsi, ma gels, ndi onyamula mankhwala. Zitha kuthandiza mankhwala kuti asungunuke m'madzi ndikuwongolera kuchuluka kwa mankhwalawo.
Makampani azakudya: HPMC, monga chowonjezera chazakudya, imagwiritsidwa ntchito ngati emulsification, thickening, ndi moisturizing. Muzowotcha, zimatha kusintha ductility ndi kukhazikika kwa mtanda. HPMC imagwiritsidwanso ntchito kwambiri mu ayisikilimu, zakumwa ndi zakudya zopanda mafuta.
Makampani omanga: M'makampani omanga, HPMC nthawi zambiri imagwiritsidwa ntchito ngati matope opangira matope, omwe amatha kupititsa patsogolo ntchito yomanga, kusunga madzi komanso kulimba kwamatope.
Zodzoladzola: Mu zodzoladzola, AnxinCel®HPMC amagwiritsidwa ntchito makamaka ngati thickener, suspending wothandizira ndi stabilizer, ndipo chimagwiritsidwa ntchito mankhwala monga zonona nkhope, shampu, ndi gel osakaniza shawa.
Mtengo wa HPMCndi madzi osungunuka komanso osakanikirana kwambiri a cellulose omwe amatha kupanga njira yowonekera ya colloidal m'madzi. Si zosungunulira, koma mkulu maselo pawiri kuti akhoza kupasuka m'madzi. Kusungunuka kwake kumawonetseredwa bwino kusungunuka m'madzi, koma osasungunuka muzitsulo zambiri za organic. Makhalidwe awa a HPMC kupanga chimagwiritsidwa ntchito m'mafakitale ambiri, kuphatikizapo mankhwala, chakudya, zomangamanga, ndi zodzoladzola.
Nthawi yotumiza: Feb-17-2025