Iphunga le-hydroxypropyl methylcellulose lithinta kanjani ikhwalithi?

Yimiphi imiphumela yobukhulu bephunga ku-hydroxypropyl methylcellulose:

Ukwenziwa kwei-hydroxypropyl methylcellulose: Phatha i-cellulose yekotini ecolisisiwe nge-lye ku-35-40°C isigamu sehora, cindezela, uchoboze i-cellulose, bese ukhula kahle ku-35°C, ukuze izinga elimaphakathi le-polymerization ye-alkali etholiwe libe ngaphakathi kwebanga elidingekayo lemicu ngaphakathi. Faka i-alkali fiber eketheni ye-etherification, engeza i-propylene oxide ne-methyl chloride ngokulandelana, bese u-etherify ku-50-80°C amahora ama-5, ingcindezi ephezulu ingaba ngu-1.8MPa. Bese wengeza inani elifanele le-hydrochloric acid ne-oxalic acid emanzini ashisayo ku-90°C ukuze ugeze izinto ukuze wandise ivolumu. Khipha amanzi ku-centrifuge. Geza ngamanzi kuze kube yilapho kungathathi hlangothi. Uma okuqukethwe komswakama kwezinto kungaphansi kuka-60%, komise ngomfudlana womoya oshisayo ku-130°C kuze kube yilapho okuqukethwe komswakama kungaphansi kuka-5%.

I-HPMC ekhiqizwa ngendlela ye-solvent isebenzisa i-toluene ne-isopropanol njenge-solvents. Uma ukuwasha kungalungile, kuzosala iphunga elincane. Njengamanje, ikhwalithi ye-hydroxypropyl methylcellulose yasekhaya i-HPMC iyahlukahluka kakhulu, futhi intengo iyahlukahluka kakhulu, okwenza kube nzima kumakhasimende ukwenza ukukhetha okufanele. Lena inkinga yenqubo yokuwasha, ayithinti ukusetshenziswa futhi ayikho inkinga, i-HPMC emsulwa akufanele inuke i-ammonia, isitashi notshwala;I-HPMCivame ukuhogela zonke izinhlobo zamaphunga, noma ngabe ayinambitheki, izozwakala inzima. Kodwa-ke, i-hydroxypropyl methylcellulose ekhiqizwa abakhiqizi abaningi inephunga elinamandla kakhulu kanye nephunga elimnandi. Ikhwalithi ayilingani neze.

I-Hypromellose itholakala ngokufaka ukotini ocoliwe ngoketshezi olungavamile ukuze kutholakale i-alkaline cellulose, bese kungezwa i-solvent, i-etherification agent, i-toluene, kanye ne-isopropanol ukuze kuphendulwe i-etherification, kuncishiswe ukuwasha, komiswe, kuchotshozwe, njll. ukuze kutholakale imikhiqizo eqediwe. Nokho, kuzoba nephunga, ukuze abasebenzisi bakwazi ukulisebenzisa ngokuzethemba.