Phapang pakeng tsa hydroxypropyl starch le Hydroxypropyl methyl cellulose

Hydroxypropyl starch le hydroxypropyl methyl cellulose (HPMC) ka bobeli ke li-polysaccharide tse fetotsoeng tse sebelisoang liindastering tse fapaneng, ho kenyeletsoa lijo, meriana, litlolo le kaho. Leha li tšoana ka tsela e itseng, li na le liphapang tse fapaneng mabapi le sebopeho sa lik'hemik'hale, thepa le ts'ebeliso. Mona ke liphapang tse kholo lipakeng tsa hydroxypropyl starch le HPMC:

Sebopeho sa Lik'hemik'hale:

1. Setache sa Hydroxypropyl:
   • Hydroxypropyl starch ke starch e fetotsoeng e fumanoang ka ho hlahisa lihlopha tsa hydroxypropyl ho molek'hule ea starch.
   • Setache ke polysaccharide e entsoeng ka diyuniti tsa glucose tse hokahantsweng hammoho ke dibonto tsa glycosidic. Hydroxypropylation e kenyelletsa ho nkela dihlopha tsa hydroxyl (-OH) sebakeng sa molek'hule ya starch ka dihlopha tsa hydroxypropyl (-CH2CHOHCH3).
2. Hydroxypropyl Methyl Cellulose (HPMC):
   • HPMC ke ether e fetotsoeng ea cellulose e fumanoang ka ho hlahisa lihlopha tsa hydroxypropyl le methyl ka har'a molek'hule ea cellulose.
   • Cellulose ke polysaccharide e entsoeng ka diyuniti tsa glucose tse hokahantsweng hammoho ke dibonto tsa glycosidic tsa β(1→4). Hydroxypropylation e hlahisa dihlopha tsa hydroxypropyl (-CH2CHOHCH3), ha methylation e hlahisa dihlopha tsa methyl (-CH3) mokokotlong wa cellulose.

Thepa:

1. Ho qhibiliha ha metsi:
   • Hangata starch ea Hydroxypropyl e qhibiliha metsing a chesang empa e ka 'na ea bontša ho qhibiliha ho fokolang metsing a batang.
   • HPMC e qhibiliha metsing a batang le a chesang, e etsa ditharollo tse hlakileng, tse tiileng. Ho qhibiliha ha HPMC ho itshetlehile ka tekanyo ya phetolo (DS) le boima ba dimolek'hule ba polymer.
2. Ho tsikinyeha:
   • Setache sa Hydroxypropyl se ka 'na sa bontša litšobotsi tse ntlafatsang viscosity, empa viscosity ea sona ka kakaretso e tlase ha e bapisoa le HPMC.
   • HPMC e tsebahala ka thepa ea eona e ntle ea ho tenya le ho fetola viscosity. Viscosity ea litharollo tsa HPMC e ka fetoloa ka ho fetola mahloriso a polymer, DS, le boima ba limolek'hule.

Likopo:

1. Lijo le Meriana:
   • Setache sa Hydroxypropyl se atisa ho sebelisoa e le setenya, se tiisang, le se etsang hore ho be le jelling lihlahisoa tsa lijo tse kang sopho, lisoso le lijo tse tsoekere. E ka boela ea sebelisoa mefuteng ea meriana.
   • HPMC e sebelisoa haholo lijong, meriana le litlolong e le sethibela-mafu, se kopanyang, se tiisang mocheso, se etsang filimi, le se etsang hore letlalo le lokolloe ka taolo. Hangata e fumanoa lihlahisoa tse kang matlapa, litlolo, litlolo le lintho tsa tlhokomelo ea botho.
2. Kaho le Thepa ea Kaho:
   • HPMC e sebelisoa haholo indastering ea kaho e le tlatsetso lihlahisoa tse thehiloeng samenteng tse kang likhomaretsi tsa thaele, li-mortar, li-render le li-plaster. E fana ka ho boloka metsi, ho sebetsa habonolo, ho khomarela le ts'ebetso e ntlafetseng lits'ebetsong tsena.

Qetello:

Leha starch ea hydroxypropyl le HPMC ka bobeli e le li-polysaccharide tse fetotsoeng tse nang le mesebetsi e tšoanang, li na le libopeho tse fapaneng tsa lik'hemik'hale, thepa le lits'ebetso. Hydroxypropyl starch e sebelisoa haholo-holo lijong le lits'ebetsong tsa meriana, ha HPMC e sebelisoa haholo lijong, meriana, litlolong le thepa ea kaho. Khetho pakeng tsa starch ea hydroxypropyl le HPMC e itšetlehile ka litlhoko tse khethehileng tsa ts'ebeliso e reriloeng.