Ho ba le seretse se tlaase sa HPMC:HPMC 400 se sebediswa haholoholo bakeng sa seretse se ikgomaretsang, empa hangata se kentswe kantle ho naha.
Lebaka: Viscosity e tlase, leha ho boloka metsi ho le tlase, empa ho leka-lekana ho hotle, 'me bongata ba seretse bo phahame.
Viscosity e mahareng le e tlase:hydroxypropyl methylcelluloseHPMC 20000-40000 e sebediswa haholoholo bakeng sa sekgomaretsi sa thaele, sesebediswa sa ho thibela ho petsoha, seretse se thibelang ho petsoha, seretse se kopanyang mocheso, jj.
Lebaka: ho sebetsa hantle, ho eketsa metsi hanyane, ho ba thata haholo ho kopanya seretse.
1. Morero o ka sehloohong oa hydroxypropyl methylcellulose (HPMC) ke ofe?
——A: HPMC e sebelisoa haholo thepa ea kaho, liphahlo, li-resin tsa maiketsetso, li-ceramic, meriana, lijo, masela, temo, litlolo, koae le liindasteri tse ling. HPMC e ka aroloa ka: sehlopha sa kaho, sehlopha sa lijo le sehlopha sa meriana ho latela morero. Hona joale, boholo ba lihlahisoa tsa lapeng ke sehlopha sa kaho. Sehlopha sa kaho, palo ea phofo ea putty e kholo haholo, hoo e ka bang 90% e sebelisetsoa phofo ea putty, 'me karolo e setseng e sebelisetsoa seretse sa samente le sekhomaretsi.
2. Ho na le mefuta e 'maloa ea hydroxypropyl methylcellulose (HPMC), 'me phapang ke efe tšebelisong ea eona?
——Karabo: HPMC e ka aroloa ka mofuta oa hang-hang le mofuta oa hot-melting. Lihlahisoa tsa hang-hang li hasana kapele metsing a batang 'me li nyamela ka metsing. Nakong ena, mokelikeli ha o na viscosity, hobane HPMC e hasana feela ka metsing 'me ha e na ho qhibiliha ha sebele. Kamora metsotso e ka bang 2, viscosity ea mokelikeli e ile ea eketseha butle-butle, ea etsa colloid e bonaletsang e nang le viscous. Lihlahisoa tse qhibilihang ka mocheso, ha li kopana le metsi a batang, li ka hasana kapele ka metsing a chesang, 'me tsa nyamela ka metsing a chesang. Ha mocheso o theohela mochesong o itseng (sehlahisoa sa k'hamphani ea rona ke likhato tse 65 tsa Celsius), viscosity e hlaha butle-butle ho fihlela e etsa colloid e bonaletsang e nang le viscous. Mofuta oa hot-melting o ka sebelisoa feela ka phofo ea putty le seretse. Ka sekhomaretsi sa metsi le pente, ketsahalo ea ho bokellana e tla etsahala 'me e ke ke ea sebelisoa. Mofuta oa hang-hang o na le mefuta e mengata ea ts'ebeliso. E ka sebelisoa ka phofo ea putty le seretse, hammoho le ka sekhomaretsi sa metsi le pente, ntle le lithibelo leha e le life.
3. Mekhoa ea ho qhaqha ha hydroxypropyl methylcellulose (HPMC) ke efe?
——Karabo: Mokhoa oa ho qhala metsi a chesang: Kaha HPMC ha e qhibilihe ka metsing a chesang, HPMC e ka qhalanngoa ka ho lekana ka metsing a chesang mohatong oa pele, ebe e qhibilihisoa ka potlako ha e pholile. Mekhoa e 'meli e tloaelehileng e hlalosoa ka tsela e latelang:
1) Kenya metsi a chesang a hlokahalang ka setshelong 'me u a futhumatse ho fihlela ho 70°C. Hydroxypropyl methylcellulose e ile ea eketsoa butle-butle ka ho hlohlelletsa butle, qalong HPMC e ile ea phaphamala holim'a metsi, 'me butle-butle ea etsa lerōle, le ileng la pholisoa ka ho hlohlelletsa.
2), eketsa 1/3 kapa 2/3 ea metsi a hlokahalang ka setshelong, 'me u a futhumatse ho fihlela ho 70 ° C, ho latela mokhoa oa 1), hasanya HPMC, lokisa slurry ea metsi a chesang; ebe u eketsa metsi a batang a setseng metsing a chesang.
Mokhoa oa ho kopanya phofo: Kopanya phofo ea HPMC le lintho tse ling tse ngata tse nang le phofo, kopanya hantle ka mochini o kopanyang, ebe u eketsa metsi ho qhibiliha, ebe HPMC e ka qhibiliha ka nako ena ntle le ho kopana, hobane ho na le HPMC e nyane feela sekhutlong se seng le se seng se senyenyane. Phofo e tla qhibiliha hang ha e kopana le metsi. ——Mokhoa ona o sebelisoa ke bahlahisi ba phofo ea putty le seretse. [Hydroxypropyl methylcellulose (HPMC) e sebelisoa e le setei se teteaneng le se bolokang metsi ka har'a seretse sa phofo ea putty.]
4. U ka ahlola boleng ba hydroxypropyl methylcellulose (HPMC) joang ka bonolo le ka tlhaho?
——Karabo: (1) Bosweu: Le hoja bosweu bo ke ke ba tseba hore na HPMC e bonolo ho e sebedisa, mme haeba ho eketswa sesebediswa se kgantshang nakong ya tlhahiso, se tla ama boleng ba yona. Leha ho le jwalo, boholo ba dihlahiswa tse ntle di na le bosweu bo botle. (2) Botle: Botle ba HPMC ka kakaretso ke letlowa la 80 le letlowa la 100, mme letlowa la 120 le le tlase. Bongata ba HPMC e hlahiswang Hebei ke letlowa la 80. Ha botle bo le bonyenyane, bo molemo. (3) Phetisetso: Kenya hydroxypropyl methylcellulose (HPMC) ka metsing ho etsa colloid e bonaletsang, mme o hlahlobe phetisetso ya yona. Ha phetisetso e phahame, e molemo, e leng se bontshang hore ho na le dintho tse sa qhibiliheng ho yona. Ho kenella ha reactor e otlolohileng ka kakaretso ho molemo, mme reactor e otlolohileng e mpe le ho feta, empa ho ke ke ha thwe boleng ba reactor e otlolohileng bo betere ho feta ba reactor e otlolohileng, mme ho na le mabaka a mangata a etsang qeto ya boleng ba sehlahiswa. (4) Matla a kgoheli a itseng: ha matla a kgoheli a itseng a le maholo, boima bo boima bo betere. Matla a khoheli a itseng a maholo, ka kakaretso hobane dikahare tsa hydroxypropyl ho yona di phahame, mme dikahare tsa hydroxypropyl di phahame, ho boloka metsi ho betere.
5. Bongata ba hydroxypropyl methylcellulose (HPMC) ka har'a phofo ea putty?
——Karabo: Bongata ba HPMC bo sebediswang ditshebedisong tse sebetsang bo fapana ho latela boemo ba lehodimo, mocheso, boleng ba khalsiamo ya molora wa lehae, foromo ya phofo ya putty le "boleng bo hlokoang ke bareki". Ka kakaretso, e pakeng tsa 4 kg le 5 kg. Mohlala, boholo ba phofo ya putty Beijing ke 5 kg; boholo ba phofo ya putty Guizhou ke 5 kg hlabula le 4.5 kg mariha;
6. Ke bokae bo nepahetseng ba hydroxypropyl methylcellulose (HPMC)?
——Karabo: Phofo ea putty ka kakaretso ke yuan tse 100,000, 'me seretse se batla ho feta, 'me ho bonolo ho se sebelisa ka yuan tse 150,000. Ho feta moo, karolo ea bohlokoa ka ho fetisisa ea HPMC ke ho boloka metsi, e lateloa ke ho teteana. Phofong ea putty, ha feela ho boloka metsi ho le molemo 'me viscosity e le tlase (70,000-80,000), hoa khoneha hape. Ehlile, viscosity e phahame, 'me ho boloka metsi ho molemo. Ha viscosity e feta 100,000, phello ea viscosity ho boloka metsi ha e ngata.
7. Lipontšo tse ka sehloohong tsa tekheniki tsa hydroxypropyl methylcellulose (HPMC) ke life?
——Karabo: Bongata ba Hydroxypropyl le viscosity, basebelisi ba bangata ba tsotella matšoao ana a mabeli. Ha hydroxypropyl e le ngata, ho boloka metsi ho ba betere. Viscosity e phahameng, ho boloka metsi, ho ba betere (ho fapana le ho ba ho feletseng), le viscosity e phahameng, tšebeliso e betere ka har'a seretse sa samente.
8. Lisebelisoa tse ka sehloohong tsa hydroxypropyl methylcellulose (HPMC) ke life?
—— A: Lisebelisoa tse ka sehloohong tse tala tsa hydroxypropyl methylcellulose (HPMC): k'hothone e hloekisitsoeng, methyl chloride, propylene oxide, lisebelisoa tse ling tse tala li kenyelletsa alkali e flake, asiti, toluene, isopropanol, jj.
9. Karolo e ka sehloohong ea HPMC ts'ebelisong ea phofo ea putty ke efe, hona na ho na le k'hemistri efe kapa efe?
——Karabo: HPMC e na le mesebetsi e meraro ea ho teteana, ho boloka metsi le ho haha ka har'a phofo ea putty. Ho teteana: Cellulose e ka teteana ho emisa, ho boloka tharollo e tšoana le e tsitsitseng, le ho hanela ho thekesela. Ho boloka metsi: Etsa hore phofo ea putty e ome butle, 'me e thuse karabelo ea calcium ea molora tlas'a ts'ebetso ea metsi. Kaho: Cellulose e na le phello ea ho tlotsa, e ka etsang hore phofo ea putty e sebetse hantle. HPMC ha e kenelle karabelong efe kapa efe ea lik'hemik'hale 'me e bapala karolo e thusang feela. Ho eketsa metsi phofong ea putty le ho e beha leboteng ke karabelo ea lik'hemik'hale. Ka lebaka la ho thehoa ha lintho tse ncha, tlosa phofo ea putty leboteng leboteng, u e sila hore e be phofo, 'me u e sebelise hape. E ke ke ea sebetsa, hobane lintho tse ncha (calcium carbonate) li se li entsoe. ) holimo. Likarolo tse ka sehloohong tsa phofo ea khalsiamo ea molora ke: motsoako oa Ca(OH)2, CaO le CaCO3 e nyane, CaO+H2O=Ca(OH)2 —Ca(OH)2+CO2=CaCO3↓+H2O Khalsiamo ea molora metsing le moeeng Tlas'a ketso ea CO2, calcium carbonate ea hlahisoa, ha HPMC e boloka metsi feela 'me e thusa karabelo e betere ea khalsiamo ea molora, 'me ha e kenelle karabelong efe kapa efe ka boeona.
10. HPMC ke ether ya cellulose e seng ya ionic, jwale e seng ya ionic ke eng?
- Karabo: Ka mantsoe a tloaelehileng, li-non-ion ke lintho tse sa ioning ka metsing. Ionization e bolela mokhoa oo ka oona electrolyte e aroloang ho ba li-ion tse tsamaeang ka bolokolohi ka har'a solvent e itseng (joalo ka metsi, joala). Mohlala, sodium chloride (NaCl), letsoai le jeoang letsatsi le letsatsi, lea qhibiliha ka metsing 'me lea ioning ho hlahisa li-ion tsa sodium tse tsamaeang ka bolokolohi (Na+) tse nang le positive charge le li-ion tsa chloride (Cl) tse nang le negative charge. Ke hore, ha HPMC e kenngoa ka metsing, ha e arohane le li-ion tse nang le charge, empa e teng ka mokhoa oa limolek'hule.
Nako ea poso: Mphalane-17-2022