Hydroxypropyl Methylcellulose (HPMC) ni iki?

Hydroxypropyl Methylcellulose (HPMC)ni eteri ya cellulose idafite ionic ikozwe mu bikoresho bya polymer karemano - ipamba itunganyijwe cyangwa ifu y'ibiti binyuze mu gutunganya alkali hamwe n'uburyo butandukanye bwo guhindura imikorere y'imiti. HPMC ifite ubushobozi bwo gushonga neza, ihora ihindagurika mu bushyuhe kandi ikora filime. Ni ibikoresho by'ingenzi bya shimi bifite akamaro kanini. Ikoreshwa cyane mu bwubatsi, mu buvuzi, mu biribwa, mu mavuta yo kwisiga n'ahandi.

1. Imiterere y'ibinyabutabire n'imiterere y'ibanze

Igice cy'ingenzi cya HPMC ni uko amwe mu matsinda ya hydroxyl muri molekile ya selulosi asimburwa na methyl (–CH₃) na hydroxypropyl (–CH₂CHOHCH₃), bityo bigahinduka eteri ya selulosi yahinduwe. Bitewe n'uko amatsinda ya hydrophilic na hydrophobic aba mu miterere yayo ya molekile, ifite imikorere myiza cyane ku buso no gukora filime.

HPMC ni ifu cyangwa granule y'umweru cyangwa idasembuye, nta mpumuro cyangwa uburyohe, kandi ishobora gushonga mu mazi akonje kugira ngo ikore umuti wa colloidal ubonerana cyangwa ufite umwuka mubi gato. Ntishongera mu mazi ashyushye, ethanol, chloroform na ether, ariko ishongera mu bintu bimwe na bimwe bivanze (nk'imiti ya methanol/amazi, ethanol/amazi).

Imiterere ifatika ya HPMC irimo

Ubucucike bugaragara: hafi 0.3 ~ 0.5 g / cm³;

pH ihamye: pH y'umuti w'amazi ihamye hagati ya 3 ~ 11;

Gushyushya: Umuti wa HPMC ufite ubushobozi bwo gushyushya. Iyo ushyushye ku bushyuhe runaka, uhinduka mu cyiciro ukamera nk'umuti wa gel, hanyuma ugasubira mu mimerere y'umuti nyuma yo gukonja;

Imikorere yo hejuru: Ifite ubushobozi bwiza bwo gukurura amazi, gukwirakwiza amazi mu kirere no kuyabika neza;

Kubora: Kubera ko bikomoka ku bimera kandi ntibigira uburozi, ni byiza ku bidukikije kandi birabora.

2. Uburyo bwo gukora

Ubusanzwe HPMC ikorwa muri selulose karemano binyuze mu nzira zikurikira:

Uburyo bwo gukora alkaline: Shyira ipamba ryatunganyijwe cyangwa igiti mu gihe cy'ubushyuhe bwa alkaline kugira ngo uce umunyururu wa molekile wa cellulose kandi wongere imikorere y'uburyo bwo gukora;

Uburyo bwo gukwirakwiza etherization: Guhuza na methyl chloride na propylene oxide mu gihe cy'ubushyuhe n'umuvuduko bikwiye kugira ngo byinjizemo amatsinda ya methyl na hydroxypropyl;

Gukuraho ibintu bidafite aho bibogamiye, gukaraba no kumisha: Kuraho ibintu byakuweho n'ibindi bintu bitarakozweho, hanyuma ubime mu bicuruzwa byarangiye;

Gusya no gupima: Shyira umusaruro wumye mu ngano ikenewe hanyuma ushyiremo umusaruro warangiye.

3. Ahantu hakuru hakoreshwa

3.1. Inganda z'ubwubatsi

HPMC ikoreshwa cyane mu nganda z'ubwubatsi, ikoreshwa cyane cyane mu byuma byumye bivanze, kole z'amatafari, ibikoresho bya gypsum, ibintu bishyushya ubushyuhe, hasi higenga n'ibindi bikoresho, ifite imirimo ikurikira:

Amazi menshi abikwa kugira ngo hirindwe ko mortironi itakaza amazi imburagihe;

Kongera ubushobozi bwo gufatana no kunoza imikorere y'ubwubatsi;

Kunoza imikorere y'ubwubatsi no kurwanya kugwa;

Genzura igihe cyo gushyiraho no gutemba kw'isima.

3.2. Inganda zikora imiti

HPMC ikoreshwa nk'agapira k'ibinini, kole y'ibinini, ibikoresho birekura vuba, emulsifier, nibindi mu gukora imiti. Ni ikintu gisanzwe gikoreshwa mu miti gifite ibi bikurikira:

Ntirihumanya, ntiritera umujinya, kandi rishobora gufatwa mu kanwa;

Imiterere myiza yo gukora filime, ishobora gukoreshwa mu kugenzura igipimo cyo kurekura imiti;

Ishobora gukoreshwa nk'ibikoresho fatizo bya capsules z'ibikomoka ku bimera kugira ngo isimbuze gelatin;

Imiterere ya Thermogel ikwiriye mu kurekura imiti igabanya ubushyuhe mu buryo bugenzurwa.

3.3. Inganda z'ibiribwa

Mu gutunganya ibiribwa, HPMC ikoreshwa cyane cyane nk'imvange, ikungahaye ku gukurura, itera imbaraga, ifata neza, n'ibindi. Urugero:

Nk'ikintu gifata amazi kandi kigateza imbere ibiryo bitetse;

Kunoza uburyohe n'imikorere y'ibinyobwa mu binyobwa;

Nk'ikintu gikomeza amazi no kunoza ingirabuzima fatizo mu nyama;

Ikoreshwa mu gusimbuza amavuta n'ibinure mu biribwa bifite ibinure bike kugira ngo habeho uburyohe.

3.4. Ibikoresho byo kwisiga n'ibikomoka ku binyabutabire bya buri munsi

HPMC ikoreshwa cyane mu bikoresho byo kwita ku ruhu, shampoo, amenyo yo koza uruhu, amavuta yo gusukura isura, nibindi, kandi ikora imirimo ikurikira:

Sisitemu zo gukurura no gushimangira emulsion;

Kunoza uburyo ibicuruzwa bikwirakwira no kunoza uburyo biryoha;

Gukora firime no gutanga ingaruka nziza zo kumesa;

Ishobora gukoreshwa mu gutegura jeli zibonerana cyangwa emulsions.

3.5. Izindi nganda

Inganda zikora irangi: zikoreshwa nk'imashini igabanya ubushyuhe n'isukari mu irangi rishingiye ku mazi;

Ubuhinzi: bukoreshwa nk'umuti ugabanya ubukana bw'imiti yica udukoko n'ifumbire mvaruganda;

Inganda zicapa: zikoreshwa nk'ubudodo n'ubukorikori mu gucapa wino;

Ibikoresho bya ceramic n'ibikoresho by'ubwubatsi: bikoreshwa nk'ubukorikori n'ibumba mu gihe cyo gushushanya.

4. Umutekano no kurengera ibidukikije

HPMC ikomoka ku bimera karemano kandi ifite ubushobozi bwo guhuza neza n'ibinyabuzima kandi irabora. Ntabwo ari uburozi kandi nta ngaruka igira ku mubiri w'umuntu iyo ikoreshejwe mu rugero rukwiye, kandi yujuje ibisabwa ku biryo n'imiti. Ntiyanduza ibidukikije, ishobora kwangirika mu bihe bisanzwe, kandi ntabwo izateza ibibazo ku bidukikije.

Hydroxypropyl methylcellulose (HPMC), nk'umusemburo wa cellulose ufite imikorere myiza kandi ukoreshwa mu buryo bwagutse, ni inyongeramusaruro y'ingenzi mu nganda za none. Kubera imiterere yayo myiza y'umubiri n'imiti, umutekano no kurengera ibidukikije, HPMC ikomeje kugira uruhare runini mu nzego nyinshi. Bitewe n'iterambere ry'ubutabire bw'ibidukikije n'ibitekerezo by'iterambere rirambye,agace k'ikoreshwa rya HPMC kazakomeza kwaguka, kandi amahirwe yo gutera imbere kwayo ni manini.