Kodi hydroxypropyl methylcellulose ndi chiyani?

1. Maonekedwe ndi kusungunuka

HPMC nthawi zambiri imakhala yoyera kapena yoyera, yopanda fungo, yopanda pake komanso yopanda poizoni. Ikhoza kusungunuka m'madzi ozizira ndi zosungunulira zina (monga zosungunulira zosakaniza monga ethanol / madzi ndi acetone / madzi), koma sizisungunuka mu ethanol yoyera, etha ndi chloroform. Chifukwa cha mawonekedwe ake osakhala a ionic, sichidzakumana ndi electrolytic reaction mumadzi amadzimadzi ndipo sichidzakhudzidwa kwambiri ndi pH mtengo.

2. Viscosity ndi rheology

HPMC amadzimadzi njira ali thickening wabwino ndi thixotropy. Mitundu yosiyanasiyana ya AnxinCel®HPMC ili ndi ma viscosity osiyanasiyana, ndipo kuchuluka kwake ndi 5 mpaka 100000 mPa·s (2% aqueous solution, 20°C). Yankho lake limasonyeza pseudoplasticity, ndiko kuti, kumeta ubweya wonyezimira, ndipo ndi yoyenera pazochitika zogwiritsira ntchito monga zokutira, slurries, zomatira, ndi zina zomwe zimafuna rheology yabwino.

3. Kutentha kwa gelation

Pamene HPMC ndi usavutike mtima mu madzi, ndi mandala njira amachepetsa ndi gel osakaniza aumbike pa kutentha. Pambuyo kuzirala, gel osakaniza adzabwerera ku njira yothetsera. Mitundu yosiyanasiyana ya HPMC imakhala ndi kutentha kwa gel osakaniza, nthawi zambiri pakati pa 50 ndi 75 ° C. Katunduyu ndi wofunikira kwambiri pakumanga matope ndi makapisozi amankhwala.

4. Zochita zapamtunda

Chifukwa mamolekyu a HPMC ali ndi magulu a hydrophilic ndi hydrophobic, amawonetsa zochitika zina zapamtunda ndipo amatha kuchita nawo ntchito yolimbikitsa, yobalalitsa komanso yokhazikika. Mwachitsanzo, mu zokutira ndi emulsions, HPMC akhoza kusintha bata la emulsion ndi kupewa sedimentation wa pigment particles.

5. Hygroscopicity

HPMC ili ndi hygroscopicity inayake ndipo imatha kuyamwa chinyezi m'malo a chinyezi. Chifukwa chake, m'mapulogalamu ena, chidwi chiyenera kulipidwa pakusindikiza kusindikiza kuti mupewe kuyamwa kwa chinyezi ndi kuphatikiza.

6. Katundu wopanga mafilimu

HPMC ikhoza kupanga filimu yolimba komanso yowonekera, yomwe imagwiritsidwa ntchito kwambiri muzakudya, mankhwala (monga zopangira zokutira) ndi zokutira. Mwachitsanzo, m'makampani opanga mankhwala, filimu ya HPMC ingagwiritsidwe ntchito ngati zokutira piritsi kuti zithandizire kukhazikika kwamankhwala ndikuwongolera kumasulidwa.

7. Biocompatibility ndi chitetezo

HPMC si poizoni ndi vuto lililonse, ndipo akhoza bwinobwino zimapukusidwa ndi thupi la munthu, choncho chimagwiritsidwa ntchito m'minda ya mankhwala ndi chakudya. Monga chithandizo chamankhwala, nthawi zambiri amagwiritsidwa ntchito popanga mapiritsi otulutsidwa mosalekeza, zipolopolo za kapisozi, ndi zina zambiri.

8. pH kukhazikika kwa yankho

HPMC imakhala yokhazikika mu pH ya 3 mpaka 11, ndipo siwonongeka mosavuta kapena imatenthedwa ndi asidi ndi alkali, kotero ingagwiritsidwe ntchito m'machitidwe osiyanasiyana a mankhwala, monga zipangizo zomangira, mankhwala a tsiku ndi tsiku ndi mankhwala opangira mankhwala.