Hydroxypropyl methylcellulose (HPMC)he mea hoʻohana maʻamau i ka cellulose derivative me kahi ākea o nā noi, ʻoi aku ma nā ʻano o nā lāʻau lapaʻau, nā mea hoʻonaninani, nā meaʻai, a me nā mea kūkulu hale. ʻAʻole ia he mea hoʻoheheʻe, akā he polymer hiki ke hoʻoheheʻe i ka wai a hana i kahi hopena colloidal akaka. ʻO ka solubility o AnxinCel®HPMC e pili ana i ka helu a me ke kūlana o ka methyl a me ka hydroxypropyl substituents i loko o kona ʻano mole.
1. Nā waiwai kumu o ka hydroxypropyl methylcellulose
Loaʻa ka Hydroxypropyl methylcellulose e ka methylation a me ka hydroxypropylation o cellulose. ʻO ka cellulose ponoʻī he polysaccharide kūlohelohe kiʻekiʻe i loaʻa i loko o nā paia o nā mea kanu. ʻO ka hoʻolālā kemika o HPMC ka nui o nā ʻāpana glucose, ʻo ia nā molekole kaulahao lōʻihi i hoʻopili ʻia e nā paʻa β-1,4 glycosidic. I loko o kēia ʻano molekala, ua hoʻololi ʻia kekahi mau pūʻulu hydroxyl e ka methyl (-OCH₃) a me ka hydroxypropyl (-C₃H₇OH), e hāʻawi ana i ka solubility maikaʻi a me nā waiwai kino a me nā mea kemika.
Hoʻopili ʻia ka solubility o HPMC e ka molecular structure a loaʻa i nā ʻano penei:
Hiki ke hoʻoheheʻe wai: Hiki i ka HPMC ke hana i kahi hopena viscous i ka wai a hemo koke. Ua pili loa kona solubility i ka mahana o ka wai a me ke kaumaha mole o HPMC.
ʻO ka viscosity kiʻekiʻe: Ma kahi hoʻopaʻapaʻa, hōʻike ka hopena o HPMC i kahi viscosity kiʻekiʻe, ʻoi aku ka nui o ke kaumaha molekala kiʻekiʻe a me ke kiʻekiʻe.
ʻO ke kūpaʻa wela: He kūpaʻa maikaʻi ka HPMC ma kekahi ʻano o nā mahana a ʻaʻole maʻalahi ka decompose, no laila aia kekahi mau pono i ke kaʻina hana wela.
2. Ka hikiwawe o HPMC
ʻO ka HPMC he mea hiki ke hoʻoheheʻe ʻia i ka wai, akā ʻaʻole ia e hoʻoheheʻe ʻia e nā mea hoʻoheheʻe a pau. ʻO kāna hana hoʻoheheʻe ʻana e pili ana i ka polarity o ka mea hoʻoheheʻe a me ka pilina ma waena o nā molekole solvent a me nā molekala HPMC.
Wai: Hiki ke hoʻoheheʻe ʻia ka HPMC i ka wai. ʻO ka wai kāna mea hoʻoheheʻe maʻamau, a i ka wā o ka hoʻoheheʻe ʻana, e hana nā molekala AnxinCel®HPMC i nā paʻa hydrogen me nā molekole wai e hoʻokō ai i ka hemo. Hoʻopili ʻia ke kiʻekiʻe o ka hoʻoheheʻe ʻia e nā mea e like me ke kaumaha molekala o HPMC, ke degere o ka methylation a me ka hydroxypropylation, ka mahana, a me ka waiwai pH o ka wai. ʻO ka maʻamau, ʻoi aku ka maikaʻi o ka solubility o HPMC ma kahi ʻano pH kūʻokoʻa.
ʻO nā mea hoʻoheheʻe kino: ʻaneʻane hiki ʻole ke hoʻoheheʻe ʻia ka HPMC i ka hapa nui o nā mea hoʻoheheʻe kūlohelohe, e like me nā waiʻona, nā eter, a me nā hydrocarbons. ʻO kēia no ka mea, aia nā pūʻulu hydrophilic hydroxyl a me nā hui lipophilic methyl a me nā pūʻulu hydroxypropyl. ʻOiai he pili ikaika kona i ka wai, ʻaʻohe kūpono me ka hapa nui o nā mea hoʻoheheʻe organik.
Hoʻoheheʻe wai wela: I ka wai mahana (maʻa mau 40 ° C a 70 ° C), hoʻoheheʻe koke ʻia ka HPMC a hōʻike ka hopena i hoʻoheheʻe ʻia i kahi viscosity kiʻekiʻe. Ke piʻi aʻe ka mahana, e piʻi ka dissolution rate a me ka solubility, akā i nā mahana kiʻekiʻe loa, hiki ke hoʻopili ʻia ka viscosity o ka hopena.
3. Noi o HPMC
Ma muli o kona hoʻoheheʻe wai maikaʻi, haʻahaʻa haʻahaʻa, a me ka viscosity hiki ke hoʻololi ʻia, hoʻohana nui ʻia ka HPMC i nā ʻoihana like ʻole.
ʻoihana lāʻau lapaʻau: Ma ka ʻoihana lāʻau lapaʻau, hoʻohana nui ʻia ka HPMC i ka hoʻomākaukau hoʻokuʻu mau ʻana o nā lāʻau lapaʻau, ka hoʻoheheʻe papa, nā gels, a me nā mea lawe lāʻau. Hiki iā ia ke kōkua i nā lāʻau lapaʻau e hoʻoheheʻe paʻa i ka wai a hoʻoponopono i ka wikiwiki o ka hoʻokuʻu ʻana i ka lāʻau.
ʻOihana meaʻai: HPMC, ma ke ʻano he mea hoʻohui meaʻai, hoʻohana mau ʻia no ka emulsification, mānoanoa, a me ka moisturizing. I loko o nā mea i kālua ʻia, hiki iā ia ke hoʻomaikaʻi i ka ductility a me ka paʻa o ka palaoa. Hoʻohana mau ʻia ʻo HPMC i ka hauʻulu, nā mea inu a me nā meaʻai haʻahaʻa momona.
ʻOihana hana: I ka ʻoihana kūkulu, hoʻohana pinepine ʻia ʻo HPMC ma ke ʻano he mānoanoa no ke kūkulu ʻana i ka pahū, hiki ke hoʻomaikaʻi i ka hana hana, ka paʻa ʻana o ka wai a me ka ikaika paʻa o ka mortar.
Mea Hoʻomaʻamaʻa: Ma nā mea hoʻonaninani, hoʻohana nui ʻia ʻo AnxinCel®HPMC ma ke ʻano he mānoanoa, ka mea hoʻopaneʻe a me ka stabilizer, a hoʻohana nui ʻia i nā huahana e like me nā ʻili maka, nā shampoos, a me nā gel wai.
HPMChe mea hoʻoheheʻe ʻia i ka wai a me ka viscous cellulose derivative i hiki ke hana i kahi hopena colloidal akaka i loko o ka wai. ʻAʻole ia he mea hoʻoheheʻe, akā he hui molekala kiʻekiʻe e hiki ke hoʻoheheʻe i ka wai. Hōʻike nui ʻia kona solubility i ka solubility maikaʻi i ka wai, akā ʻaʻole hiki ke hoʻoheheʻe ʻia i ka hapa nui o nā mea hoʻoheheʻe organik. Hoʻohana nui ʻia kēia mau hiʻohiʻona o ka HPMC i nā ʻoihana he nui, me nā lāʻau lapaʻau, nā meaʻai, ke kūkulu ʻana, a me nā mea hoʻonaninani.
Ka manawa hoʻouna: Feb-17-2025