Ingemuva kanye Uhlolojikelele
I-Cellulose ether iyisisetshenziswa samakhemikhali e-polymer esihle esetshenziswa kabanzi eyenziwe nge-polymer cellulose yemvelo ngokwelashwa ngamakhemikhali. Ngemva kokukhiqizwa kwe-cellulose nitrate ne-cellulose acetate ekhulwini le-19, osokhemisi baye basungula uchungechunge lokuphuma kwe-cellulose kwama-cellulose ethers amaningi, futhi izinkambu ezintsha zokufaka isicelo ziye zatholwa ngokuqhubekayo, ezibandakanya imikhakha eminingi yezimboni. Imikhiqizo ye-cellulose ether efana ne-sodiumI-carboxymethyl cellulose (CMC), i-ethyl cellulose (EC), i-hydroxyethyl cellulose (HEC), i-hydroxypropyl cellulose (HPC), i-methyl hydroxyethyl cellulose (MHEC)futhii-methyl hydroxypropyl cellulose (MHPC)kanye namanye ama-cellulose ethers aziwa ngokuthi "i-industrial monosodium glutamate" futhi asetshenziswe kakhulu ekubholeni amafutha, ukwakhiwa, ukumboza, ukudla, imithi kanye namakhemikhali nsuku zonke.
I-Hydroxyethyl methyl cellulose (MHPC) iyimpushana emhlophe engenaphunga, enganambitheki, engenabuthi engancibilika emanzini abandayo ukuze yakhe isixazululo se-viscous esisobala. Inezici zokuqina, ukubopha, ukusabalalisa, i-emulsifying, ukwenza ifilimu, ukumisa okwesikhashana, i-adsorbing, i-gelling, i-surface esebenzayo, ukugcina umswakama nokuvikela i-colloid. Ngenxa yezindawo ezisebenzayo zesisombululo esinamanzi, singasetshenziswa njenge-ejenti yokuvikela ye-colloidal, i-emulsifier ne-dispersant. Isixazululo samanzi se-Hydroxyethyl methylcellulose sine-hydrophilicity enhle futhi iyi-ejenti esebenza kahle yokugcina amanzi. Ngenxa yokuthi i-hydroxyethyl methylcellulose iqukethe amaqembu e-hydroxyethyl, inekhono elihle lokunqanda isikhutha, ukuzinza okuhle kwe-viscosity kanye nokumelana nesikhutha ngesikhathi sokugcina isikhathi eside.
I-Hydroxyethyl methylcellulose (HEMC) ilungiswa ngokwethula izingxenye ze-ethylene oxide (MS 0.3~0.4) ku-methylcellulose (MC), futhi ukumelana nosawoti wayo kungcono kunama-polymers angashintshiwe. Izinga lokushisa le-gelation le-methylcellulose nalo liphakeme kunalelo le-MC.
Isakhiwo
Isici
Izici eziyinhloko ze-hydroxyethyl methylcellulose (HEMC) yilezi:
1. Ukuncibilika: Kuncibilika emanzini nakwezinye izincibilikisi eziphilayo. I-HEMC ingancibilika emanzini abandayo. Ukugxila kwayo okuphezulu kunqunywa kuphela yi-viscosity. I-Solubility iyahlukahluka ngokuya nge-viscosity. I-viscosity ephansi, i-solubility enkulu.
2. Ukumelana nosawoti: Imikhiqizo ye-HEMC i-non-ionic cellulose ethers futhi ayiwona ama-polyelectrolyte, ngakho-ke iqinile ngokuqhathaniswa nezixazululo ezinamanzi lapho usawoti wensimbi noma ama-electrolyte ephilayo ekhona, kodwa ukwengezwa ngokweqile kwama-electrolyte kungabangela i-gelation kanye nemvula.
3. Umsebenzi ongaphezulu: Ngenxa yomsebenzi osebenzayo ongaphezulu wesixazululo esinamanzi, singasetshenziswa njenge-colloidal protective agent, emulsifier kanye ne-dispersant.
4. Ijeli elishisayo: Uma isixazululo samanzi semikhiqizo ye-HEMC sishiswa ekushiseni okuthile, siba yi-opaque, ama-gel, kanye ne-precipitates, kodwa uma sipholile ngokuqhubekayo, sibuyela esimweni sokuqala sesisombululo, futhi izinga lokushisa lapho le gel kanye nemvula kwenzeka khona ngokuyinhloko Ngokusekelwe kubo ama-lubricant, ama-suspending aid, ama-emuls protective, njll.
5. Ukungabi namandla kwe-Metabolic kanye nephunga eliphansi kanye nephunga elimnandi: I-HEMC isetshenziswa kakhulu ekudleni nasemithini ngoba ngeke igaywe futhi inephunga eliphansi kanye nephunga elimnandi.
6. Ukumelana nesikhutha: I-HEMC inokumelana kahle nesikhutha kanye nokuzinza okuhle kwe-viscosity ngesikhathi sokugcina isikhathi eside.
7. Ukuzinza kwe-PH: I-viscosity yesisombululo esinamanzi semikhiqizo ye-HEMC ayithinteki neze i-asidi noma i-alkali, futhi inani le-pH lizinzile ngokuqhathaniswa phakathi kwebanga elingu-3.0 ukuya ku-11.0.
Isicelo
IHydroxyethyl methylcellulose ingasetshenziswa njenge-ejenti evikelayo ye-colloidal, i-emulsifier kanye ne-dispersant ngenxa yomsebenzi wayo osebenza phezulu kusisombululo esinamanzi. Izibonelo zokusetshenziswa kwayo zimi kanje:
1. Umphumela we-hydroxyethyl methylcellulose ekusebenzeni kukasimende. IHydroxyethyl methylcellulose iyimpushana emhlophe engenaphunga, enganambitheki, engenabuthi engancibilika emanzini abandayo ukuze yakhe isixazululo se-viscous esisobala. Inezici zokuqina, ukubopha, ukusabalalisa, i-emulsifying, ukwenza ifilimu, ukumisa okwesikhashana, i-adsorbing, i-gelling, i-surface esebenzayo, ukugcina umswakama nokuvikela i-colloid. Njengoba isixazululo esinamanzi sinomsebenzi osebenzayo, singasetshenziswa njenge-ejenti yokuvikela ye-colloidal, i-emulsifier ne-dispersant. Isixazululo samanzi se-Hydroxyethyl methylcellulose sine-hydrophilicity enhle futhi iyi-ejenti esebenza kahle yokugcina amanzi.
2. Upende wokusiza oguquguqukayo kakhulu ulungiswa, owenziwe ngezinto zokusetshenziswa ezilandelayo ezingxenyeni ngesisindo: 150-200 g wamanzi angcolile; 60-70 g ye-emulsion ehlanzekile ye-acrylic; 550-650 g we-calcium enzima; 70-90 g we-talcum powder; Isisekelo se-cellulose isisombululo se-aqueous 30-40g; isixazululo samanzi se-lignocellulose 10-20g; ifilimu-forming aid 4-6g; i-antiseptic ne-fungicide 1.5-2.5g; i-disperant 1.8-2.2g; i-ejenti yokumanzisa 1.8-2.2g; 3.5-4.5g; i-ethylene glycol 9-11g; Isixazululo samanzi se-hydroxyethyl methylcellulose senziwa ngokuncibilikisa i-2-4% ye-hydroxyethyl methylcellulose emanzini; Isixazululo samanzi se-lignocellulose senziwe nge-1-3 % I-Lignocellulose yenziwa ngokuncibilika emanzini.
Ukulungiselela
Indlela yokulungiselela i-hydroxyethyl methyl cellulose, indlela ukuthi ukotini ocolisisiwe usetshenziswa njengempahla eluhlaza, futhi i-ethylene oxide isetshenziswa njenge-etherification agent ukuze kulungiswe i-hydroxyethyl methyl cellulose. Izingxenye zesisindo zezinto zokusetshenziswa zokulungiselela i-hydroxyethyl methylcellulose zimi kanje: izingxenye ezingama-700-800 ze-toluene ne-isopropanol ingxube njenge-solvent, izingxenye ezingama-30-40 zamanzi, izingxenye ezingama-70-80 ze-sodium hydroxide, izingxenye ezingama-80-85 zikakotini ocwengekile, indandatho izingxenye ezingama-20-28 ze-oxy methyl-90, i-methyl chloride e90, 16-19 izingxenye ze-glacial acetic acid; izinyathelo eziqondile yilezi:
Isinyathelo sokuqala, ku-kettle yokusabela, engeza ingxube ye-toluene ne-isopropanol, amanzi, ne-sodium hydroxide, ukushisa kufika ku-60-80 ° C, hlala ufudumele imizuzu engu-20-40;
Isinyathelo sesibili, i-alkalization: pholisa izinto ezingenhla ku-30-50 ° C, engeza ukotini ocolisisiwe, fafaza i-toluene ne-isopropanol ingxube ye-solvent, vacuumize ku-0.006Mpa, ugcwalise i-nitrogen esikhundleni se-3, futhi wenze ngemva kokushintshwa kwe-Alkalinization, izimo ze-alkalization yilezi: isikhathi se-alkalization singamahora angu-2, kuya ku-50 ° C ° C;
Isinyathelo sesithathu, i-etherification: ngemva kokuqedwa kwe-alkalization, i-reactor ikhishwa ku-0.05-0.07MPa, futhi i-ethylene oxide ne-methyl chloride yengezwe imizuzu engu-30-50; isigaba sokuqala se-etherification: 40-60 ° C, 1.0-2.0 Amahora, ingcindezi ilawulwa phakathi kuka-0.15 no-0.3Mpa; isigaba sesibili se-etherification: 60～90℃, 2.0～2.5 amahora, ingcindezi ilawulwa phakathi kuka-0.4 no-0.8Mpa;
Isinyathelo sesine, ukungathathi hlangothi: engeza i-acetic acid elinganisiwe kusengaphambili ku-kettle yemvula, cindezela ku-etherified material for neutralization, uphakamise izinga lokushisa libe ngu-75-80 ° C ukuze uthole imvula, izinga lokushisa likhuphukela ku-102 ° C, futhi inani le-pH litholwa ukuthi liyi-6 Ngehora lesi-8, ukuchithwa kuqediwe; ithangi le-desolventization ligcwele amanzi kampompi aphathwe idivayisi ye-osmosis e-90 ° C kuya ku-100 ° C;
Isinyathelo sesihlanu, ukugeza kwe-centrifugal: into esiteji sesine i-centrifuged ngokusebenzisa i-screw centrifuge enezingqimba, futhi impahla ehlukanisiwe idluliselwa ku-tank yokugeza egcwele amanzi ashisayo kusengaphambili ukuze kugezwe impahla;
Isinyathelo sesithupha, ukomiswa kwe-centrifugal: izinto eziwashiwe zidluliselwa esomisini nge-screw centrifuge enezingqimba, futhi izinto zomisiwe zomiswe ku-150-170 ° C, futhi izinto ezomile ziyachotshozwa futhi zihlanganiswe.
Uma kuqhathaniswa nobuchwepheshe obukhona bokukhiqiza i-cellulose ether, ukusungulwa kwamanje kusebenzisa i-ethylene oxide njenge-etherification agent ukuze kulungiswe i-hydroxyethyl methyl cellulose, enokumelana okuhle nokukhunta ngenxa yokuqukatha amaqembu e-hydroxyethyl. Inokuqina okuhle kwe-viscosity kanye nokumelana nesikhutha ngesikhathi sokugcina isikhathi eside. Ingasetshenziswa esikhundleni sama-cellulose ethers.
Isikhathi sokuthumela: Apr-25-2024