Ingabe i-hypromellose ne-HPMC ziyefana

I-Hypromellose ne-HPMC (i-hydroxypropyl methylcellulose) ziyinhlanganisela efanayo, naphezu kokwaziwa ngamagama ahlukene. Womabili la magama asetshenziswa ngokushintshana ukuze abhekisele kwinhlanganisela yamakhemikhali ethola ukusetshenziswa okubanzi ezimbonini ezihlukahlukene, okuhlanganisa ezemithi, ukudla, izimonyo, nezokwakha.

Isakhiwo Sekhemikhali:

I-Hypromellose: Lena i-semi-synthetic, inert, i-viscoelastic polymer etholakala ku-cellulose. Yakhiwe ngamakhemikhali nge-cellulose eshintshwe ngamaqembu e-hydroxypropyl namaqembu e-methyl. Lezi zinguquko zithuthukisa ukunyibilika kwayo, i-viscosity, nezinye izici ezifiselekayo zezinhlelo zokusebenza ezahlukahlukene.

I-HPMC (Hydroxypropyl Methylcellulose): Le yinhlanganisela efanayo ne-hypromellose. I-HPMC isifinyezo esisetshenziselwa ukubhekisela kule nhlanganisela, emele isakhiwo sayo samakhemikhali esihlanganisa amaqembu e-hydroxypropyl kanye ne-methyl cellulose.

Izakhiwo:

Ukunyibilika: Kokubili i-hypromellose kanye ne-HPMC kuncibilika emanzini nasezincibilikisini eziphilayo, kuye ngezinga lokushintshwa kanye nesisindo samangqamuzana se-polymer.

I-Viscosity: Lawa ma-polymer akhombisa izinhlobonhlobo zama-viscosity kuye ngesisindo samangqamuzana awo kanye nezinga lokushintshwa. Zingasetshenziswa ukulawula i-viscosity yezixazululo futhi zithuthukise ukuzinza kokwakhiwa kwezinhlelo zokusebenza ezihlukahlukene.

Ukwakhiwa Kwefilimu: I-Hypromellose/HPMC ingakha amafilimu lapho esakazwa esixazululweni, okuwenza abe yigugu ezinhlelweni zokumbozwa kwemithi, lapho anganikeza khona izakhiwo zokukhululwa okulawulwayo noma avikele izithako ezisebenzayo ezicini zemvelo.

I-ejenti ejiyayo: Kokubili i-hypromellose ne-HPMC zivame ukusetshenziswa njengama-ejenti okuqina emikhiqizweni eyahlukene, okuhlanganisa ukudla, izimonyo, nemithi. Banikeza ukuthungwa okubushelelezi futhi bathuthukise ukuzinza kwama-emulsions nokumiswa.

Izicelo:

Ezemithi: Embonini yezemithi, i-hypromellose/HPMC isetshenziswa kabanzi njenge-excipient kumafomu womthamo oqinile womlomo njengamaphilisi, amaphilisi, nama-granules. Inikeza imisebenzi ehlukahlukene efana ne-binder, i-disintegrant, ne-ejenti yokukhishwa okulawulwayo.

Imboni Yokudla: I-Hypromellose/HPMC isetshenziswa embonini yokudla njenge-thickener, emulsifier, kanye ne-stabilizer emikhiqizweni efana namasoso, okokugqoka, nezinto zokubhaka. Ingathuthukisa ukuthungwa, i-viscosity, kanye nempilo yeshalofu yemikhiqizo yokudla.

Izimonyo: Ezimonyoni, i-hypromellose/HPMC isetshenziswa ekwenziweni kokhilimu, izinto zokuthambisa, namajeli ukuze kuhlinzekwe isilawuli se-viscosity, i-emulsification, kanye nezakhiwo zokugcina umswakama.

Ukwakhiwa: Ezintweni zokwakha, i-hypromellose/HPMC isetshenziswa njenge-ejenti yokuqina kanye nokugcina amanzi emikhiqizweni esekwe usimende njengezinamatheliso zamathayili, ama-mortars, nama-renders.

I-hypromellose ne-HPMC zibhekisela esakhiweni esifanayo—okuphuma kokunye kwe-cellulose okushintshwe ngamaqembu e-hydroxypropyl kanye ne-methyl. Babonisa izakhiwo ezifanayo futhi bathola izinhlelo zokusebenza ezinhlobonhlobo kuzo zonke izimboni ezihlanganisa ezemithi, ukudla, izimonyo, nezokwakha. Ukuguquguquka kwalawa magama kwesinye isikhathi kungaholela ekudidekeni, kepha amele i-polymer eguquguqukayo efanayo esetshenziswa ngezindlela ezahlukahlukene.