Ziziphi izinto ezisekwe kwi-HPMC?

I-HPMC, okanye i-hydroxypropyl methylcellulose, i-polymer eguquguqukayo ephuma kwi-cellulose, into yendalo efumaneka kwiindonga zeseli zezityalo. Izinto ezisekelwe kwi-HPMC zifumene ingqwalasela ebalulekileyo kuwo wonke amashishini ahlukeneyo ngenxa yeepropati zabo ezizodwa kunye noluhlu olubanzi lwezicelo.

Intshayelelo nge-HPMC:

IHydroxypropyl methylcellulose (HPMC) yi-semi-synthetic, i-polymer enyibilikayo emanzini ephuma kwi-cellulose. Ngokuqhelekileyo isetyenziswa njenge-thickener, i-binder, i-emulsifier, kunye ne-ejenti yokwenza ifilimu kumashishini ahlukeneyo, kubandakanywa amayeza, ukutya, ukwakhiwa, izimonyo, kunye neemveliso zokhathalelo lomntu.

Iimpawu zeMathiriyeli esekwe kwi-HPMC:

Ukunyibilika kwamanzi: I-HPMC ibonisa ukunyibilika okugqwesileyo kwamanzi, iyenza ilungele ukusetyenziswa kwizisombululo ezinamanzi kunye nemixube.

Ulawulo lwe-Viscosity: Isebenza njenge-agent esebenzayo yokuqina, ivumela ulawulo oluchanekileyo phezu kwe-viscosity yezisombululo kunye nokuqulunqwa.

IiPropati zokuSebenza ifilimu: I-HPMC inokwenza iifilimu ezicacileyo, eziguquguqukayo xa zomisiwe, ziyenza ibe luncedo kwiingubo, iifilimu, kunye neenkqubo zokuhanjiswa kweziyobisi ezilawulwayo.

Ukuzinza: Izinto ezisekelwe kwi-HPMC zinika uzinzo olulungileyo kuluhlu olubanzi lwe-pH kunye neemeko zobushushu.

I-Biodegradability: Ithathwe kwi-cellulose, i-HPMC i-biodegradable, iyenza ukuba ihambelane nokusingqongileyo xa kuthelekiswa neepolima zokwenziwa.

3.Izicelo zeziXhobo ezisekelwe kwi-HPMC:

(1) Amachiza:

Ukuqulunqwa kweThebhulethi: I-HPMC isetyenziswa ngokubanzi njenge-binder kunye ne-disintegrant kwi-tablet formulations, inikezela ukukhululwa okulawulwayo kunye nokuphuculwa kokuchithwa kweziyobisi.

Ulwakhiwo lwemixholo: Isetyenziswa kwizithambiso, iikhrimu, kunye neejeli njengesilungisi se-viscosity kunye ne-emulsifier.

Iinkqubo eziLawulwayo zokuKhululwa: Iimatriki ezisekelwe kwi-HPMC ziqeshwe kwiinkqubo zokukhutshwa okuzinzileyo kunye nezijoliswe kuzo zokuhanjiswa kweziyobisi.

(2) Ushishino lokutya:

Iarhente yokutyebisa: I-HPMC isetyenziselwa ukujiya kunye nokuzinzisa iimveliso zokutya ezinje ngeesosi, isuphu, kunye nezimuncumuncu.

Ukutshintshwa kwaManqatha: Ingasetyenziselwa ukutshintshwa kwamafutha kwiimveliso zokutya ezinamafutha aphantsi okanye ezingenamafutha ukuphucula ukuthungwa kunye nomlomo.

(3) Ulwakhiwo:

Udaka kunye neePlasta: I-HPMC iphucula ukusebenza, ukunamathela, kunye nokugcinwa kwamanzi kwiidaka ezisekelwe kwi-samente kunye ne-plasters.

I-Tile Adhesives: Iphucula amandla okudibanisa kunye nexesha elivulekileyo lokunamathelisa i-tile, ukuphucula ukusebenza kwabo.

(4) Izinto zokuthambisa kunye noKhathalelo loBuqu:

Iimveliso zoKhathalelo lweNwele: I-HPMC idityaniswe kwiishampu, izilungiseleli, kunye neemveliso zesitayile ngenxa yokutyeba kunye neempawu zokwenza ifilim.

Ukuqulunqwa koLondolozo lweLusu: Isetyenziswe kwi-lotions, i-creams, kunye ne-sunscreens njenge-stabilizer kunye ne-emulsifier.

Iindlela zokuHlanganisa ze-HPMC:

I-HPMC idityaniswe ngoluhlu lweekhemikhali zokuguqulwa kweselulosi. Inkqubo ibandakanya i-etherification ye-cellulose kunye nepropylene oxide kunye ne-methyl chloride ukwazisa i-hydroxypropyl kunye namaqela e-methyl, ngokulandelanayo. Iqondo lokutshintshwa (DS) lwe-hydroxypropyl kunye namaqela e-methyl anokulawulwa ukulungisa iimpawu ze-HPMC kwizicelo ezithile.

(5) Uphuculo lwakutsha nje kunye neeNdlela zoPhando:

I-Nanocomposites: Abaphandi baphonononga ukufakwa kwe-nanoparticles kwiimatriki ze-HPMC ukunyusa iipropathi zoomatshini, umthamo wokulayisha iziyobisi, kunye nokuziphatha okulawulwayo kokukhululwa.

Ushicilelo lwe-3D: Ii-hydrogels ezisekelwe kwi-HPMC ziphandwa ukuze zisetyenziswe kwi-3D bioprinting ye-tissue scaffolds kunye neenkqubo zokuhanjiswa kweziyobisi ngenxa ye-biocompatibility yazo kunye neepropati ezithintekayo.

Izinto eziSmart Material: Izinto ezisekelwe kwi-HPMC zenziwa ukuba ziphendule kwi-stimuli yangaphandle efana ne-pH, ubushushu, kunye nokukhanya, okwenza kube lula ukuphuhliswa kweenkqubo zokuhanjiswa kweziyobisi kunye nezinzwa.

I-Bioinks: Ii-bioinks ezisekelwe kwi-HPMC zifumana ingqwalasela ngenxa yokukwazi kwazo kwizicelo ze-bioprinting, ezivumela ukuveliswa kwezinto eziyinkimbinkimbi zokwakha kunye nokusebenza kweeseli eziphezulu kunye nokulawulwa kwendawo.

Izixhobo ezisekwe kwi-HPMC zibonelela ngentaphane yeenzuzo kuwo wonke amashishini ahlukeneyo, kubandakanya amayeza, ukutya, ulwakhiwo, kunye nezinto zokuthambisa. Ngokuhlanganiswa kwabo okuyingqayizivele kweempawu, kubandakanywa ukunyibilika kwamanzi, ukulawulwa kwe-viscosity, kunye ne-biodegradability, izinto ezisekelwe kwi-HPMC ziyaqhubeka nokuqhuba izinto ezintsha kwisayensi yezinto eziphathekayo, okwenza kube lula ukuphuhliswa kweenkqubo zokuhanjiswa kweziyobisi eziphambili, ukutya okusebenzayo, izinto zokwakha ezizinzileyo, kunye nezicubu ze-bioprinted. Njengoko uphando kulo mmandla luqhubela phambili, sinokulindela impumelelo eyongezelelekileyo kunye nokusetyenziswa kwenoveli yemathiriyeli esekwe kwi-HPMC kungekudala.