I-HPMC kunye ne-PEG zisetyenziselwa ntoni?

IHydroxypropyl methylcellulose (HPMC) kunye nepolyethylene glycol (PEG) zikhompawundi ezimbini eziguquguqukayo ezinezicelo ezahlukeneyo kumashishini ahlukeneyo.

IHydroxypropyl Methylcellulose (HPMC):

Amachiza: I-HPMC isetyenziswa ngokubanzi kuqulunqo lwamayeza njenge-thickener, binder, ifilimu yangaphambili, kunye ne-arhente yokukhululwa okuqhubekayo kwiingubo zethebhulethi kunye neematriki ezikhutshwayo ezilawulwayo.

Ukuhanjiswa kweziyobisi ngomlomo: Isebenza njenge-viscosity modifier kwiifom zedosi yolwelo ezifana ne-syrups, ukumiswa, kunye ne-emulsions, ukuphucula ukuzinza kunye nokuvumba.

I-Ophthalmic Formulations: Kwi-eye drops kunye nezisombululo ze-ophthalmic, i-HPMC isebenza njenge-lubricant kunye ne-viscosity-enhancing agent, yandisa ixesha lokuqhagamshelana neyeza kunye ne-ocular surface.

Amalungiselelo omxholo: I-HPMC iqeshwe kwiikhrimu, iigels, kunye ne-ointments njenge-ejenti yokuqina, inika ukuhambelana okufunwayo kunye nokwandisa ukusasazeka kokwakheka.

Ukunxitywa kwamanxeba: Isetyenziswa kwizinxibo zamanxeba esekwe kwi-hydrogel ngenxa yeempawu zayo zokugcina ukufuma, ukwenza lula ukuphiliswa kwenxeba kunye nokukhuthaza imekobume yenxeba efumileyo.

Umzi-mveliso wokwakha: I-HPMC yongezwa kwiidaka ezisekwe kwisamente, iiplasta, kunye nokuncamatheliswa kweethayile ukuphucula ukusebenza, ukugcinwa kwamanzi, kunye neempawu zokuncamathelisa.

Ishishini lokuTya: Kwimveliso yokutya, i-HPMC isebenza njenge-thickener, i-stabilizer, kunye ne-emulsifier, iphucula ukuthungwa, ubomi beshelufu, kunye ne-mouthfeel. Ngokuqhelekileyo ifumaneka kwiimveliso zokubhaka, ezinye iindlela zobisi, iisosi, kunye nokunxiba.

Iimveliso zoNonophelo loBuqu: I-HPMC idityaniswe kwizinto zokuthambisa kunye nezinto zokhathalelo lomntu ezifana nezithambiso, iikhrimu, kunye neemveliso zokhathalelo lweenwele njenge-arhente yokuqina kunye nokumisa, ukuphucula ukuhambelana kwemveliso kunye nokuzinza.

Iipeyinti kunye neeNgqungquthela: I-HPMC isetyenziselwa iipeyinti ezisekelwe emanzini kunye neengubo zokulawula i-viscosity, ukuthintela ukugoba, kunye nokuphucula ukunamathela kwi-substrates.

Polyethylene Glycol (PEG):

I-Pharmaceuticals: I-PEG isetyenziswe ngokubanzi kwimiqulu ye-pharmaceutical formulations njenge-ejenti yokunyibilikisa, ngokukodwa kumachiza angenawo amanzi, kwaye njengesiseko seenkqubo ezahlukeneyo zokuhanjiswa kweziyobisi ezifana ne-liposomes kunye ne-microspheres.

IiLaxatives: I-PEG-based laxatives isetyenziselwa ukunyanga ukuqhina ngenxa yesenzo sazo se-osmotic, ukutsala amanzi emathunjini kunye nokuthambisa ilindle.

Izithambiso: I-PEG isetyenziswa kwimixube yezithambiso ezifana neekhrimu, izinto zokuthambisa, kunye neshampoo njenge-emulsifier, i-humectant, kunye ne-solvent, iphucula uzinzo kunye nokuvakala kwemveliso.

Izithambisi zobuqu: Izithambisi ezisekwe kwi-PEG zisetyenziswa kwiimveliso zokhathalelo lomntu kunye nezithambisi zesondo ngenxa yokuguda kwazo, ukungancamatheli kunye nokunyibilika kwamanzi.

I-Polymer Chemistry: I-PEG iqeshwe njenge-precursor kwi-synthesis yeepolymers ezahlukeneyo kunye ne-copolymers, igalelo kwisakhiwo kunye neempawu zabo.

Iimpendulo zeMichiza: I-PEG isebenza njengendawo yokusabela okanye i-solvent kwi-organic synthesis kunye ne-chemical reactions, ngakumbi kwiimpendulo ezibandakanya iikhompawundi ezingevayo ngamanzi.

Ishishini lelaphu: I-PEG isetyenziswa ekusetyenzweni kwelaphu njengesithambiso kunye ne-arhente yokugqiba, iphucula ukuvakala kwelaphu, ukuqina, kunye neempawu zokudaya.

Ishishini lokutya: I-PEG isetyenziswa njenge-humectant, i-stabilizer, kunye ne-thickener kwiimveliso zokutya ezifana nempahla ebhakiweyo, i-confectionery, kunye nezinto zobisi, ukuphucula ukuthungwa kunye nokuphila kweshelufu.

Izicelo ze-Biomedical: I-PEGylation, inkqubo yokunamathisela i-PEG ikhonkco kwi-biomolecules, iqeshwe ukuguqula i-pharmacokinetics kunye ne-biodistribution yeeprotheni zonyango kunye ne-nanoparticles, ukwandisa ixesha labo lokujikeleza kunye nokunciphisa i-immunogenicity.

I-HPMC kunye ne-PEG zifumana usetyenziso oluxhaphakileyo kuwo wonke amayeza, ukutya, izinto zokuthambisa, ulwakhiwo, kunye namanye amashishini ahlukeneyo, ngenxa yeepropathi zazo eziguquguqukayo kunye nokusebenza kwazo.