Iimpawu zetekhnoloji yobushushu obuphezulu be-hydroxypropyl methylcellulose

IHydroxypropyl methylcellulose (HPMC)yinto ebalulekileyo yeekhemikhali, esetyenziswa ngokubanzi kwizinto zokwakha, amayeza, ukutya kunye nezinye iindawo. Ngokukodwa kushishino lokwakha, i-HPMC isetyenziswa ngokubanzi ngenxa yokusebenza kwayo kakuhle. Itekhnoloji yobushushu obuphezulu idlala indima ebalulekileyo kwimveliso kunye nokusetyenziswa kweHPMC.

1. Indima yobuchwepheshe bokushisa okuphezulu kwi-HPMC

ukuveliswa kweHydroxypropyl methylcellulose ifunyenwe ngoluhlu lweekhemikhali eziphendulayo ezifana ne-alkalization kunye ne-etherification ye-cellulose yendalo. Itekhnoloji yobushushu obuphezulu isetyenziswa ikakhulu kwizigaba zokunyibilika, ukomisa kunye nokubumba inkqubo yokusabela. Unyango oluphezulu lweqondo lokushisa alukwazi nje ukukhawuleza izinga lokuphendula, kodwa nokuphucula ubunyulu kunye nokuzinza kwemveliso.

Ukuphucula ukusebenza kakuhle

Ngaphantsi kweemeko eziphezulu zeqondo lokushisa, izinga lokuphendula le-cellulose kunye ne-sodium hydroxide likhawuleza, elikhuthaza ukuphendulwa kwe-hydroxypropyl kunye ne-methyl substitution ngaphakathi kwee-molecule ze-cellulose, ngaloo ndlela kuphuculwe i-degree of substitution (DS) kunye nokufana kwe-HPMC.

Susa ukungcola

Indawo yokushisa ephezulu inokususa ngokufanelekileyo iimveliso eziveliswe ngexesha lokuphendula, njengesisombululo se-alkali esingaphendulwanga kunye ne-solvent, kunye nokuphucula ukucoceka kwe-HPMC.

Ukuphuculwa kokumisa kakuhle

Ngexesha lenkqubo yokomisa ubushushu obuphezulu, ukufuma kweHPMC kuphuma umphunga ngokukhawuleza, kunqande imveliso kwi-agglomerating okanye i-denaturing kumaqondo obushushu aphantsi, kunye nokuphucula uzinzo kunye nokusebenza kokugcinwa kwemveliso.

2. Impembelelo yeteknoloji yobushushu obuphezulu ekusebenzeni kwe-HPMC

Itekhnoloji yobushushu obuphezulu ayichaphazeli nje kuphela ubume bomzimba we-HPMC, kodwa inefuthe elinzulu kwiimpawu zayo zekhemikhali kunye neziphumo zesicelo.

Uhlengahlengiso lwe-Viscosity

Inkqubo yobushushu obuphezulu inokulawula ngokufanelekileyo ukuhanjiswa kobunzima bemolekyuli ye-HPMC, ngaloo ndlela ilungisa i-viscosity yayo. Amaqondo obushushu aphezulu anceda ukunciphisa amathuba okuqhekeka kwetsheyina lemolekyuli, okwenza i-viscosity ye-HPMC kwisisombululo esinamanzi sizinze ngakumbi.

Ukomelezwa kokumelana nobushushu

Uzinzo olushushu lwe-HPMC luphuculwe kakhulu ngonyango lobushushu obuphezulu. Ekwakhiweni kodaka kunye ne-adhesives ye-tile, i-HPMC isenokugcina ukubambelela okulungileyo kunye neempawu ezichasayo phantsi kweemeko eziphezulu zokushisa.

Ukunyibilika okuphuculweyo

Ngexesha lenkqubo yokomisa ubushushu obuphezulu, i-microstructure ye-HPMC iphuculwe, iyenza inyibilike ngakumbi emanzini abandayo. Ngokukodwa kwiindawo zokwakha eziphantsi kweqondo lokushisa, i-HPMC inokuchithwa ngokukhawuleza kwaye yenze isisombululo esifanayo se-colloidal.

3. Ukusetyenziswa okuthe ngqo kwethekhnoloji yobushushu obuphezulu kwinkqubo yokuvelisa iHPMC

Inqanaba lokusabela kwe-Etherification

Ngokwenza ukusabela kwe-etherification kubushushu obuphezulu be-80-100 ° C, ukusabela endaweni ye-hydroxypropyl kunye namaqela e-methyl kunokukhawuleziswa, ukuze i-HPMC ibe neqondo eliphezulu lokuthatha indawo kunye nokuzinza okungcono.

Inqanaba lokumisa kunye nokutyumza

Itekhnoloji yokumisa umoya oshushu ngaphezu kwe-120 ° C ayikwazi ukususa kuphela umswakama, kodwa iphinde ithintele i-HPMC powder kwi-agglomerating ngexesha lokumisa. Emva koko, itekhnoloji yokutyumza ubushushu obuphezulu isetyenziselwa ukwenza amasuntswana e-HPMC empuphu athambileyo kwaye afane, kwaye ukusasazeka kwemveliso kuphuculwe.

Ubushushu obuphezulu bokunyanga unyango

Xa i-HPMC isetyenziselwa izinto zokwakha okanye iingubo, unyango lokunyanga ubushushu obuphezulu lunokuphucula ukuxhathisa ukuqhekeka, ukuxhathisa i-sag kunye nokusebenza kokugcinwa kwamanzi, ukuqinisekisa isiphumo esihle sokwakha kwiimeko ezinzima.

4. Izinto ezilungileyo zeteknoloji yobushushu obuphezulu kwiinkalo zesicelo se-HPMC

Izinto zokwakha

Ngaphantsi kwemekobume yobushushu obuphezulu, i-HPMC ibonisa ukutyeba okugqwesileyo kunye nokugcinwa kwamanzi kwidaka kunye ne-putty powder, ukuthintela udaka ekuphelelweni kwamanzi ngokukhawuleza kunye nokuqhekeka.

Ishishini lokupeyinta

I-HPMC edityaniswe bubushushu obuphezulu inomgangatho olungileyo kunye neziphumo ezichasayo kwipeyinti yelatex, ephucula ukuncamathela kunye nokunxiba ukuxhathisa kwengubo.

Ishishini lamachiza

Itekhnoloji yobushushu obuphezulu inokuphucula ukufana kwe-HPMC ekugqumeni kweziyobisi kunye nokuqinisekisa ukuzinza kwesiphumo sokukhululwa kwechiza.

Ukusetyenziswa kobuchwepheshe bobushushu obuphezulu beihydroxypropyl methylcelluloseayiphuculi nje ukusebenza kakuhle kwemveliso, kodwa ikwaphucula ukusebenza kwemveliso. Ngokusebenzisa inkqubo yobushushu obuphezulu, i-viscosity, i-solubility kunye nokuzinza kwe-thermal ye-HPMC iye yaphuculwa kakhulu, okwenza ukuba ibe nethemba elibanzi lesicelo kwiinkalo zokwakha, iingubo kunye neyeza. Kwixesha elizayo, kunye nokuveliswa okuqhubekayo kobuchwepheshe obuphezulu bokushisa, ukusebenza kwe-HPMC kuya kuphuculwa ngakumbi, kwenza igalelo elikhulu ekuphuhliseni izinto eziluhlaza kunye nokusingqongileyo.