IHydroxypropyl methylcellulose (HPMC)yipolymer eguquguqukayo esetyenziswa kumashishini afana namayeza, ulwakhiwo, izinto zokuthambisa, ukutya, kunye nokhathalelo lomntu. I-viscosity ye-HPMC idlala indima ebalulekileyo ekumiseleni ukufaneleka kwayo kwizicelo ezahlukeneyo. I-viscosity iphenjelelwa bubunzima bemolekyuli, iqondo lokuthatha indawo, kunye nokugxila. Ukuqonda amabakala afanelekileyo e-viscosity kubalulekile ekukhetheni i-HPMC efanelekileyo kwiimfuno ezithile zoshishino.
Umlinganiselo weViscosity
I-viscosity ye-AnxinCel®HPMC ngokuqhelekileyo ilinganiswa kwizisombululo ezinamanzi kusetyenziswa i-rotational or capillary viscometer. Iqondo lokushisa eliqhelekileyo lokuvavanya ngu-20 ° C, kwaye i-viscosity ibonakaliswe kwi-millipascal-seconds (mPa · s okanye cP, centipoise). Amabanga ahlukeneyo e-HPMC anee-viscosities ezahlukeneyo ngokuxhomekeke kwisicelo esicetywayo.
AmaBanga eViscosity kunye nezicelo zabo
Itheyibhile engezantsi ichaza amabakala e-viscosity aqhelekileyo e-HPMC kunye nezicelo ezihambelanayo:
| IBanga leViscosity (mPa·s) | Ugxininiso oluqhelekileyo (%) | Isicelo |
| 5 – 100 | 2 | I-eye drops, izongezo zokutya, ukumiswa |
| 100 - 400 | 2 | Iingubo zeetafile, izibophelelo, izincamathelisi |
| 400 - 1,500 | 2 | Izinto zokuthambisa, izithambiso, iinkqubo zokuhanjiswa kweziyobisi |
| 1,500 - 4,000 | 2 | Iiarhente zokutyebisa, iimveliso zokhathalelo lomntu |
| 4,000 - 15,000 | 2 | Ulwakhiwo (izinto zokuncamathelisa iithayile, iimveliso ezenziwe ngesamente) |
| 15,000 - 75,000 | 2 | Ukulungiswa kweziyobisi ezilawulwayo, iigrouts zokwakha |
| 75,000 - 200,000 | 2 | I-high-viscosity adhesives, ukuqiniswa kwesamente |
Izinto ezichaphazela iViscosity
Izinto ezininzi zinefuthe kwi-viscosity ye-HPMC:
Ubunzima beMolekyuli:Ubunzima bemolekyuli obuphezulu bukhokelela ekwandeni kwe-viscosity.
Isidanga soTshintsho:Umlinganiselo we-hydroxypropyl kunye namaqela e-methyl kuchaphazela ukunyibilika kunye ne-viscosity.
Ugxininiso lwesisombululo:Ukugxininiswa okuphezulu kubangela i-viscosity enkulu.
Ubushushu:I-Viscosity iyancipha ngokunyuka kobushushu.
Uvakalelo lwe-pH:Izisombululo ze-HPMC zizinzile ngaphakathi koluhlu lwe-pH lwe-3-11 kodwa lunokunciphisa ngaphandle kolu luhlu.
Ixabiso le-Shear:I-HPMC ibonisa iipropathi zokugeleza ezingezizo ezeNewtonian, okuthetha ukuba i-viscosity iyancipha phantsi koxinzelelo lokucheba.
Ukuqwalaselwa kwesicelo
Amachiza:I-HPMC isetyenziswa kwimixube yechiza ukukhululwa okulawulwayo kwaye njengesibophelelo kwiipilisi. Amanqanaba asezantsi e-viscosity (100–400 mPa·s) akhethwayo kwi-coatings, ngelixa amabanga aphezulu (15,000+ mPa·s) asetyenziselwa ukukhutshwa okuzinzileyo.
Ulwakhiwo:I-AnxinCel®HPMC isebenza njenge-arhente yokugcina amanzi kunye ne-adhesive kwiimveliso ezisekelwe kwisamente. Amanqanaba aphezulu e-viscosity (ngaphezu kwe-4,000 mPa·s) afanelekile ekuphuculeni ukusebenza kunye namandla okudibanisa.
Izithambiso kunye noNonophelo lomntu:Kwiishampu, izinto zokuthambisa, kunye neekhrimu, iHPMC isebenza njengento etyebisayo kunye nezinzisi. Amabanga aphakathi e-viscosity (400–1,500 mPa·s) abonelela ngolungelelwano olufanelekileyo phakathi kweempawu zokuthungwa kunye nokuhamba.
Ishishini lokutya:Njengesongezo sokutya (E464), i-HPMC iphucula ukuthungwa, ukuzinza, kunye nokugcinwa komswakama. Amabanga asezantsi e-viscosity (5-100 mPa·s) aqinisekisa ukusasazwa okufanelekileyo ngaphandle kokuqina okugqithisileyo.
Ukhetho lweHPMCibakala le-viscosity lixhomekeke kwisicelo esicetywayo, kunye namabanga asezantsi e-viscosity afanelekileyo kwizisombululo ezifuna ukutyeba okuncinci kunye namabakala aphezulu e-viscosity asetyenziswa ekuqulunqweni okudinga i-adhesive eqinile kunye neempawu zokuzinzisa. Ulawulo olufanelekileyo lwe-viscosity luqinisekisa ukusebenza okusebenzayo kumachiza, ukwakhiwa, ukutya, kunye namashishini okuthambisa. Ukuqonda izinto eziphembelela i-viscosity kunceda ekuphuculeni ukusetyenziswa kwe-HPMC kwizicelo ezahlukeneyo zoshishino.
Ixesha lokuposa: Feb-11-2025