Sehlahisoa sena ke 2-hydroxypropyl ether methyl cellulose, e leng sehlahisoa sa semi-synthetic. E ka hlahisoa ka mekhoa e 'meli: (1) Ka mor'a ho phekola lithara tsa k'hothone kapa likhoele tsa makhasi a lehong ka soda ea caustic, li kopantsoe le chloromethane le epoxy Propane reacts, e hloekisitsoeng le ho siloa ho e fumana; (2) Sebelisa grade e loketseng ea methyl cellulose ho phekola ka sodium hydroxide, ho itšoara ka propylene oxide tlas'a mocheso o phahameng le khatello e phahameng ho ea boemong bo loketseng, le ho e hloekisa. Boima ba molek'hule bo tloha ho 10,000 ho isa ho 1,500,000.
★ Khopolo e hloekileng ea tlhaho, e matlafatsa tšilo ea lijo le ho monya.
★ Metsi a tlaase, 5% -8%. Matla a ho monya mongobo, ha ho bonolo ho kopanya lintho tse ka hare, 'me khetla ea capsule ha e bonolo ho holofala, e fetoha brittle le ho thatafala.
★ Ha ho kotsi ea karabelo ea li-cross-link, ha ho tšebelisano, botsitso bo phahameng, kaha hydroxypropyl methylcellulose ke derivative ea cellulose, ha ho na kotsi ea ho kopana ha lintho tsa protheine ka gelatin.
★ Litlhoko tse tlase bakeng sa maemo a polokelo:
E batla e se brittle tikolohong ea mongobo o tlase, e na le botsitso bo botle mochesong o phahameng, 'me capsule ha e senyehe.
★ Maemo a tšoanang le tšebelisano e ntle:
E sebetsa ho litekanyetso tsa naha tsa pharmacopoeia, sebopeho, boholo, ponahalo le mokhoa oa ho tlatsa li lekana le li-capsules tse sekoti tsa gelatin, 'me ha ho hlokahale ho nkela lisebelisoa le likarolo sebaka.
★ Mohloli o seng oa liphoofolo, ha ho kotsi e ka bang teng ea ho hōla ha hormone kapa lithethefatsi tse setseng 'meleng oa phoofolo.
Hydroxypropyl methylcelluloseli-capsules tse se nang letho li fapane le li-capsules tse tloaelehileng tsa gelatin. Ke hydroxypropyl methylcellulose (HPMC) e entsoeng ka makhasi a lehong. Ntle le melemo ea mohopolo o hloekileng oa tlhaho, hydroxypropyl methylcellulose capsules e se nang letho hape E ka ntlafatsa ho monya le ho sila ha liprotheine, mafura le lik'habohaedreite, 'me e na le melemo ea tekheniki le litšoaneleho tseo li-capsules tse tloaelehileng tsa gelatin hollow li se nang tsona. Ka ntlafatso e tsoelang pele ea ho itlhokomela ha batho, nts'etsopele ea ho ja meroho, ho felisoa ha lefu la bohlanya ba likhomo, lefu la tlhako le molomo holim'a bophelo bo botle ba batho, le tšusumetso ea bolumeli le lintlha tse ling, lihlahisoa tse hloekileng tsa tlhaho le tsa limela li tla fetoha tataiso bakeng sa nts'etsopele ea indasteri ea capsule. .
Nako ea poso: Apr-28-2024