HPMC, kapa hydroxypropyl methylcellulose, ke polima e feto-fetohang e nkiloeng ho cellulose, ntho ea tlhaho e fumanehang maboteng a lisele tsa limela. Lisebelisoa tse thehiloeng ho HPMC li fumane tlhokomelo e kholo liindastering tse fapaneng ka lebaka la thepa ea tsona e ikhethang le mefuta e mengata ea lits'ebetso.
Selelekela ho HPMC:
Hydroxypropyl methylcellulose (HPMC) ke semi-synthetic, polymer e qhibilihang ka metsing e nkiloeng ho selulose. Hangata e sebelisoa e le setei, se tlamang, sa emulsifier, le moemeli oa ho etsa lifilimi liindastering tse fapaneng, ho kenyeletsa le meriana, lijo, kaho, litlolo, le lihlahisoa tsa tlhokomelo ea botho.
Litšobotsi tsa Lisebelisoa tse thehiloeng ho HPMC:
Ho qhibiliha ha Metsi: HPMC e bonts'a ho qhibiliha ha metsi ka mokhoa o babatsehang, ho etsa hore e be e loketseng ho sebelisoa litharollong tsa metsi le metsoako.
Taolo ea Viscosity: E sebetsa e le sesebelisoa se matla sa botenya, se lumellang taolo e nepahetseng holim'a viscosity ea tharollo le libopeho.
Thepa ea ho Etsa Lifilimi: HPMC e ka etsa lifilimi tse hlakileng, tse tenyetsehang ha li omisitsoe, e leng se etsang hore e be molemo ka ho roala, lifilimi le mekhoa e laoloang ea ho fana ka lithethefatsi.
Botsitso: Thepa e thehiloeng ho HPMC e fana ka botsitso bo botle holim'a mefuta e mengata ea pH le maemo a mocheso.
Biodegradability: Kaha e nkiloe ho selulose, HPMC e khona ho senyeha, ho e etsa hore e senyehe ha e bapisoa le li-polymer tsa maiketsetso.
3. Lits'ebetso tsa lisebelisoa tse thehiloeng ho HPMC:
(1) Meriana:
Thepa ea Letlapa: HPMC e sebelisoa haholo e le setlamo le sekoahelo mefuteng ea lipilisi, ho fana ka tokollo e laoloang le ho ntlafatsoa ha ho qhibiliha ha lithethefatsi.
Meetso ea Lihlooho: E sebelisoa ho litlolo, litlolo, le li-gel e le mofetoleli oa viscosity le emulsifier.
Lits'ebetso tse Laoloang-Tlhaloso: Matrices a thehiloeng ho HPMC a sebelisoa lits'ebetsong tsa phepelo ea lithethefatsi tse sa khaotseng le tse lebisitsoeng.
(2) Indasteri ea Lijo:
Thickening Agent: HPMC e sebedisetswa ho tiisa le ho tsitsisa dihlahiswa tsa dijo tse kang disoso, sopho, le di-dessert.
Phetoho ea Mafura: E ka sebelisoa e le sebaka sa mafura lijong tse se nang mafura a tlase kapa tse se nang mafura ho ntlafatsa sebopeho le molomo.
(3) Kaho:
Liretse le Lipolasetere: HPMC e ntlafatsa ho sebetsa, ho khomarela, le ho boloka metsi ka har'a seretse se entsoeng ka samente le li-plaster.
Li-Adhesives tsa Lithaele: E matlafatsa matla a tlamahano le nako e bulehileng ea likhomaretsi tsa lithaele, e ntlafatsa ts'ebetso ea tsona.
(4) Litlolo le Tlhokomelo ea Motho:
Lihlahisoa tsa Tlhokomelo ea Moriri: HPMC e kenyelelitsoe ka har'a li-shampoo, li-conditioner, le lihlahisoa tsa setaele bakeng sa ho tenya le ho etsa lifilimi.
Meetso ea Tlhokomelo ea Letlalo: E sebelisoa ka litlolo, litlolo, le litlolo tse sireletsang letsatsi e le ntho e etsang botsitso le emulsifier.
Mekhoa ea ho kopanya HPMC:
HPMC e entsoe ka letoto la liphetoho tsa lik'hemik'hale tsa selulose. Ts'ebetso e kenyelletsa etherification ea cellulose ka propylene oxide le methyl chloride ho hlahisa hydroxypropyl le lihlopha tsa methyl, ka ho latellana. The degree of substitution (DS) ea hydroxypropyl le lihlopha tsa methyl li ka laoloa ho hlophisa thepa ea HPMC bakeng sa lits'ebetso tse ikhethileng.
(5) Lintlafatso tsa Haufinyane le Mekhoa ea Lipatlisiso:
Nanocomposites: Bafuputsi ba ntse ba hlahloba ho kenyelletsoa ha li-nanoparticles ho matrices a HPMC ho ntlafatsa thepa ea mochine, matla a ho laela lithethefatsi, le boitšoaro bo laoloang ba tokollo.
Khatiso ea 3D: Li-hydrogel tse thehiloeng ho HPMC li ntse li fuputsoa hore li sebelisoe ho 3D bioprinting ea li-tissue scaffolds le litsamaiso tsa phepelo ea lithethefatsi ka lebaka la ho lumellana ha tsona le thepa ea tsona e ka khonehang.
Smart Materials: Thepa e thehiloeng ho HPMC e ntse e etsoa ho arabela ts'usumetso ea kantle e kang pH, mocheso le leseli, e leng se nolofalletsang nts'etsopele ea litsamaiso tse bohlale tsa phepelo ea lithethefatsi le li-sensor.
Li-bioinks: Li-bioinks tse thehiloeng ho HPMC li ntse li lebisa tlhokomelo bakeng sa bokhoni ba tsona ba lisebelisoa tsa bioprinting, tse nolofalletsang ho etsoa ha metsoako e rarahaneng ea lisele tse nang le bokhoni bo phahameng ba lisele le taolo ea sebaka.
Lisebelisoa tse thehiloeng ho HPMC li fana ka melemo e mengata ho pholletsa le liindasteri tse fapaneng, ho kenyeletsoa meriana, lijo, kaho le litlolo. Ka motsoako oa bona o ikhethang oa thepa, ho kenyeletsoa ho qhibiliha ha metsi, taolo ea viscosity, le biodegradability, lisebelisoa tse thehiloeng ho HPMC li ntse li tsoela pele ho khanna mekhoa e mecha ea saense ea lintho tse bonahalang, e leng ho nolofalletsang nts'etsopele ea mekhoa e tsoetseng pele ea ho fana ka lithethefatsi, lijo tse sebetsang, thepa ea kaho e tsitsitseng, le li-bioprinted tissues. Ha lipatlisiso lefapheng lena li ntse li tsoela pele, re ka lebella tsoelo-pele e eketsehileng le lisebelisoa tse ncha tsa lisebelisoa tse thehiloeng ho HPMC haufinyane.
Nako ea poso: May-08-2024